Dynamic loading of solids with a negative slope of the melting curve

The results of experiments on shock-wave loading of materials distinguished by a negative slope of the melting curve are reported. An anomalous situation is possible, when the material is melted by a shock wave and then a fast transition to the solid phase takes place in the expansion wave. The newly formed phase should be a nanostructural formation of the given element. Experiments confirmed the existence of the transition from the liquid to the solid phase of the nanostructural modification.     

Synthesis of Phosphonoindoprofen

Two synthetic routes to phosphonic analogues of indoprofen, a nonsteroidal anti-inflammatory drug, were developed by the cyclization of aniline 2 (method A) and by the Arbuzov reaction of corresponding alkylchloride 3 with triethylphosphite (method B).     

Sulfur Ligands. from β-Lactam Antibiotics to Contrast Agents for MRI

Abstract

NMR, IR and semi empirical Molecular Orbital PM3 studies on selected β-lactam antibiotics are reported. The role of sulfur in β-lactam antibiotics is discussed.