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131.
Mahmoudi M Amiri H Shokrgozar MA Sasanpour P Rashidian B Laurent S Casula MF Lascialfari A 《Chemical communications (Cambridge, England)》2011,47(37):10404-10406
The creation of novel engineered multimodal nanoparticles (NPs) is a key focus in bionanotechnology and can lead to deep understanding of biological processes at the molecular level. Here, we present a multi-component system made of gold-coupled core-shell SPIONs, as a new nanoprobe with signal enhancement in surface Raman spectroscopy, due to its jagged-shaped gold shell coating. 相似文献
132.
Chen L Roger J Bruneau C Dixneuf PH Doucet H 《Chemical communications (Cambridge, England)》2011,47(6):1872-1874
The palladium catalysed 5-arylation of 2-(trimethylsilyl)thiophene with aryl bromides via C-H bond functionalisation allows the synthesis of arylated silylthiophenes in only one step. 相似文献
133.
134.
Buldyreva J Guinet M Eliet S Hindle F Mouret G Bocquet R Cuisset A 《Physical chemistry chemical physics : PCCP》2011,13(45):20326-20334
The case of symmetric tops CH(3)X (X = Br, Cl, F, …) perturbed by non-polar diatoms Y(2) (Y = N(2), O(2), …) is analysed from the viewpoint of theoretical collisional broadening of their rotational lines observed in atmospheric spectra. A semi-classical approach involving an exponential representation of the scattering operator and exact trajectories governed by the isotropic potential is presented. For the first time the active molecule is strictly treated as a symmetric top and the atom-atom interactions are included in the intermolecular potential model. It is shown for the CH(3)Cl-O(2) system that these interactions contribute significantly to the line width for all values of the rotational quantum numbers J and K. Additional testing of modifications required in the semi-classical formalism for a correct application of the cumulant expansion is performed and it is shown that the use of the cumulant average on the rotational states of the perturbing molecule leads to entirely negligible effects for the not very strongly interacting CH(3)Cl-O(2) system. In order to check the theoretical predictions and to extend the scarce experimental data available in the literature to higher values of the rotational quantum numbers, new measurements of room-temperature O(2)-broadened CH(3)Cl rotational lines are carried out by a photomixing continuous-wave terahertz spectrometer. The experimental line widths extracted with a Voigt profile model demonstrate an excellent agreement with theoretical results up to very high J-values (J = 31, 37, 40, 45, 50). 相似文献
135.
Gates AJ Kemp GL To CY Mann J Marritt SJ Mayes AG Richardson DJ Butt JN 《Physical chemistry chemical physics : PCCP》2011,13(17):7720-7731
In protein film electrochemistry a redox protein of interest is studied as an electroactive film adsorbed on an electrode surface. For redox enzymes this configuration allows quantification of the relationship between catalytic activity and electrochemical potential. Considered as a function of enzyme environment, i.e., pH, substrate concentration etc., the activity-potential relationship provides a fingerprint of activity unique to a given enzyme. Here we consider the nature of the activity-potential relationship in terms of both its cellular impact and its origin in the structure and catalytic mechanism of the enzyme. We propose that the activity-potential relationship of a redox enzyme is tuned to facilitate cellular function and highlight opportunities to test this hypothesis through computational, structural, biochemical and cellular studies. 相似文献
136.
Sophie Hautphenne Guy Latouche Marie-Ange Remiche 《Methodology and Computing in Applied Probability》2011,13(1):171-192
The extinction probability of a branching process is characterized as the solution of a fixed-point equation which, for a
fairly general class of Markovian branching processes, is vector quadratic. We address the question of solving that equation,
using a mixture of algorithmic and probabilistic arguments. We compare the relative efficiency of three iterative methods
based on functional iteration, on the basis of the probabilistic interpretation of the successive iterations as well as on
the basis of traditional rate of convergence analysis. We illustrate our findings through a few numerical examples and conclude
by showing how they extend to more complex systems. 相似文献
137.
de Langlard Mathieu Lamadie Fabrice Charton Sophie Debayle Johan 《Methodology and Computing in Applied Probability》2021,23(2):549-567
Methodology and Computing in Applied Probability - The paper focuses on a new method for the inference of a parametric random spheroid from the observations of its 2D orthogonal projections. Such a... 相似文献
138.
Benoit Bachand Mohamed Atfani Bita Samim Sophie Lévesque Daniel Simard Xianqi Kong 《Tetrahedron letters》2007,48(49):8587-8589
A practical synthetic route to various 2-alkylpropane-1,3-sultones, the key intermediates for the preparation of 2-substituted homotaurines as analogs of tramiprosate, was developed. 相似文献
139.
Daniel T. Schühle Jürgen Schatz Prof. Dr. Sophie Laurent Dr. Luce Vander Elst Prof. Dr. Robert N. Muller Prof. Dr. Marc C. A. Stuart Dr. Joop A. Peters Dr. 《Chemistry (Weinheim an der Bergstrasse, Germany)》2009,15(13):3290-3296
The novel amphipilic conjugate of a calix[4]arene with four Gd–1,4,7,10‐ tetra(carboxymethyl)‐1,4,7,10‐tetraazacyclododecane (DOTA) chelates has potential as a magnetic resonance imaging contrast agent, both in its monomeric and in its micellar form. The system, illustrated here with its nuclear magnetic relaxation profile, shows good relaxivities, thanks to its high rigidity.
140.
Dr. Daniela Verga Dr. Florian Hamon Dr. Florent Poyer Dr. Sophie Bombard Dr. Marie‐Paule Teulade‐Fichou 《Angewandte Chemie (International ed. in English)》2014,53(4):994-998
We have developed a straightforward synthetic pathway to a set of six photoactivatable G‐quadruplex ligands with a validated G4‐binding motif (the bisquinolinium pyridodicarboxamide PDC‐360A) tethered through various spacers to two different photo‐cross‐linking groups: benzophenone and an aryl azide. The high quadruplex‐versus‐duplex selectivity of the PDC core was retained in the new derivatives and resulted in selective alkylation of two well‐known G‐quadruplexes (human telomeric G4 and oncogene promoter c‐myc G4) under conditions of harsh competition. The presence of two structurally different photoactivatable functions allowed the selective alkylation of G‐quadruplex structures at specific nucleobases and irreversible G4 binding. The topology and sequence of the quadruplex matrix appear to influence strongly the alkylation profile, which differs for the telomeric and c‐myc quadruplexes. The new compounds are photoactive in cells and thus provide new tools for studying G4 biology. 相似文献