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151.
152.
Guido Sello Silvana Bernasconi Fulvia Orsini Patrizia Di Gennaro 《Tetrahedron: Asymmetry》2009,20(5):563-565
The cascade use of enzymatic activities allows for the preparation of enantiomerically pure epoxides. In particular, using whole-cell biocatalysts we can prepare both (?)-[3-(oxiran-2-yl)phenyl]methanol and (?)-3-(oxiran-2-yl)benzoic acid in one-pot, two or three steps procedure. The yield is quantitative and enantiomeric purity greater than 95%. The selected biocatalysts contain a styrene monoxygenase from Pseudomonas fluorescens ST and a naphthalene dihydrodiol dehydrogenase from P. fluorescens N3, cloned and expressed in Escherichia coli. 相似文献
153.
Víctor H. Álvarez Silvana Mattedi Manuel Martin-Pastor Martín Aznar Miguel Iglesias 《Fluid Phase Equilibria》2010
This work reports the synthesis of 2-hydroxy ethylammonium oleate and bis(2-hydroxy ethyl)ammonium oleate ionic liquids, which have a long aliphatic chain as well as the study of some of their physical properties, in particular the effect of temperature on their density, speed of sound, viscosity, and refractive index. 1H and 13C NMR spectra were used to characterize the chemical structure of the species in concordance with FT-IR spectra. DOSY NMR spectra were used to determine the self-diffusion coefficients of 2-hydroxy ethylammonium oleate ionic liquid, which were consistent with the formation of a lamellar or micellar liquid crystal phase; due the similar structure, a similar aggregation in the bis(2-hydroxy ethyl)ammonium oleate ionic liquid it is expected. 相似文献
154.
Nitrile ligated transition metal complexes bearing polyfluorinated tetra(aryl)borates as counter anions are highly active initiators/mediators for various polymerization reactions. However, the methods for their preparation are still far too inefficient for widespread use in applied research or in industry. Accordingly, an improved synthesis for two of the most promising species in this assemblage of complexes, namely [Cu(C6H5CN)5][B(C6F5)4]2 and [Zn(CH3CN)4/6][B(C6F5)4]2, has been developed. This route provides easy access to pure products on a gram scale, by the reaction of copper(II)acetate and diethyl zinc with [H(OEt2)2][B(C6F5)4]. Additionally, a new route for the synthesis of the oxonium acid as precursor has been developed, allowing a fast preparation of this compound. Elementary analysis and X-ray crystal structures are in accordance with earlier results on the ease of solvent loss and theoretical studies dealing with acetonitrile-exchange reactions. 相似文献
155.
Silvana P. Ravía Ignacio Carrera Gustavo A. Seoane Silvana Vero Daniela Gamenara 《Tetrahedron: Asymmetry》2009,20(12):1393-1397
A screening of 15 fungi and yeast strains was carried out in fermentation processes to perform the diastereo- and enantioselective reduction of ethyl 2-methyl-3-oxobutanoate, to the corresponding (R1,S1)-3-hydroxy-2-methyl esters. Overall, biotransformations led to excellent conversions, as well as good to excellent diastereo- and enantioselectivities. A strain of Aureobasidium pullulans (CCM H1) was found to be the most efficient biocatalyst in terms of conversion (100%), syn:anti ratio (3:97), and enantiomeric excess (94% anti-(2S,3S) isomer). This biotransformation was successfully carried out on a preparative level as well. Other microorganisms, such as Fusarium graminearum (CCM HH 224), Aspergillus terreus (BFQU 121), Geotrichum candidum (CCM H38), Trichoderma koningii (ATCC 76666), and Aspergillus niger (CCM H21) also showed excellent diastereo- and enantioselectivities, combined with high conversions (>95% conversion, ?95% ee, and excellent syn:anti ratios). Many of the strains used in this work had scarcely been described as oxido-reducing agents, or had never been used with the substrates reported herein. 相似文献
156.
Marco Pocci Silvana Alfei Francesco Lucchesini Vincenzo Bertini Barbara Idini 《Tetrahedron》2009,65(29-30):5684-5692
Sugar-based co-polymers with saccharidic units in stable cyclic form and nanometric morphologies stabilized through crosslinking, adaptable through specific functionalizations to biochemical interaction studies with copper-containing amine oxidases, were synthesized from appropriate monomers and macromonomers. The most promising nanospherical co-polymer obtained, containing β-d-glucopyranosidic units, was employed in functionalization reactions with the help of model molecules, achieving useful transformations mainly at the 6-position and to a minor extent at the 2-position of the saccharidic system. 相似文献
157.
Silvana V. F. Gomes Alan D. C. Santos Valéria R. S. Moraes Lúcia R. R. Martins Monalisa D. Viana Arie F. Blank Edenir R. Pereira-Filho Quezia B. Cass Paulo C. L. Nogueira Péricles B. Alves 《Chromatographia》2010,72(3-4):275-280
A liquid chromatographic method with photodiode-array detection has been developed for differentiation of seven genotypes of Lippia gracilis Schauer, originated from Sergipe state (named 106 to 110) and from Bahia state (201 and 202), cultivated and collected in the rural campus of the Federal University of Sergipe. For a comparative analysis of the fingerprint chromatograms, chemometric tools were applied with exploratory methods. The genotypes were differentiated and their relationship with original place was established (Sergipe and Bahia states) by principal component analysis of the fingerprint chromatograms of both leaves and stem samples. 相似文献
158.
Tatjana Gazivoda Kraljevi? Andrea Bistrovi?Matea Dedi? Sandra Kraljevi? Paveli?Mirela Sedi? Silvana Rai?-Mali? 《Tetrahedron letters》2012,53(38):5144-5147
A series of the novel 5-alkynyl- and furo[2,3-d]pyrimidine derivatives in which the sugar moiety is replaced by a methoxymethyl (MOM) group is synthesised using the Sonogashira cross-coupling reaction under both conventional and microwave conditions, in good to excellent yields. The 5-endo-dig cyclisation of 5-alkynylpyrimidine derivatives promoted by a Pd-catalyst or base gives the corresponding furo[2,3-d]pyrimidines in good yields. 相似文献
159.
Elisandra Rigo André E. Polloni Daniela Remonatto Francieli Arbter Silvana Menoncin J. Vladimir Oliveira Débora de Oliveira Helen Treichel Susana J. Kalil Jorge L. Ninow Marco Di Luccio 《Applied biochemistry and biotechnology》2010,162(7):1881-1888
The main objective of this work was the isolation and screening of microorganisms with potential for producing lipases for the synthesis of fatty esters as well as evaluating the specificity of the enzymes produced, using different alcohols (methanol, ethanol, n-propanol, and butanol) and fatty acids (oleic and lauric acids) as substrates. Promising biocatalysts for organic synthesis were obtained in this work. The isolated strains 69F and 161Y showed ability to efficiently catalyze the reaction for production of n-propyl oleate. Other strains can also be considered of potential interest, as 74F, 111Y, and 186Y. The future development of production using different substrates could result in cheap crude lipase of high importance to industrial applicability. 相似文献
160.
Fat body cells or throphocytes of individuals during beginning of pupation (pre-pupae) of Apis mellifera were collected and studied by routine and cytochemical preparations for transmission electron microscopy (TEM). The results showed that the trophocytes present large reserves of lipids, proteins, and glycogen. Imidazole osmium treatment revealed that lipids are deposited as droplets in the cytoplasm and also within protein granules. Thiery's reaction showed the presence of glycogen inside protein granules. An acid phosphatase reaction was performed to verify the role of this enzyme in the mobilization of stored reserves during metamorphosis. Positive reaction for acid phosphatase was detected at larger protein granules, at the periphery of the large lipid droplets, and free in the cytoplasm. The contents of protein, lipid and glycogen are stored in the trophocytes at larval phase to be used during metamorphosis. The acid phosphatase present in the products stored might be responsible for their metabolization, while acid phosphatase free in cytoplasm might actuates in the trophocytes histolysis that occurs during metamorphosis for energy production. 相似文献