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971.
In this study examined is the wave interaction with a new modified perforated breakwater, consisting of a perforated front
wall, a solid back wall and a wave absorbing chamber between them with a two-layer rock-filled core. The fluid domain is divided
into three sub-domains according to the components of the breakwater. Then by means of the matched eigenfunction expansion
method, an analytical solution is obtained to assess the hydrodynamic performance of the new structure. An approach based
on a step approach method is introduced to solve the complex dispersion equations for water wave motions within two-layer
porous media. Numerical results of the present model are compared with previous limiting cases. The effects of rock fill on
the reflection coefficient and the horizontal wave force are discussed.
The project supported by the Program for Changjiang Scholars and Innovative Research Teams in Universities (IRT0420). The
English text was polished by Keren Wang. 相似文献
972.
Li-Ping Teng Hong Zeng Cai-Yan Yang He-Bin Wang Zhong-Bo Zhou 《Molecules (Basel, Switzerland)》2022,27(17)
Quorum sensing (QS) plays an important role in the production of virulence factors and pathogenicity in pathogenic bacteria and is, therefore, a hopeful target to fight against bacterial infections. During our search for natural QS inhibitors, two new xanthonolignoids (1 and 2), each existing as a racemic mixture, one new simple oxygenated xanthone (7), and eight known analogs (3–6, 8–11) were isolated from Hypericum scabrum Linn. Chiral separation of 1 yielded a pair of enantiomers 1a and 1b. The structures of these compounds were elucidated by spectroscopic analysis and ECD (electrostatic circular dichroism) calculations. All isolates were evaluated for their QS inhibitory activity against Chromobacterium violaceum. Both 9 and 10 exhibited the most potent QS inhibitory effects with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 31.25 and 62.5 μM, respectively. Crystal violet staining was used to further evaluate the biofilm inhibition potential of compounds 7, 9 and 10, and the formation of biofilms increased with decreasing drug concentration in a classic dose-dependent manner. The results of a cytotoxicity assay revealed that compounds 7, 9 and 10 exhibited no cytotoxic activity on PC-12 cells at the tested concentration. 相似文献
973.
Yuan Jia Jia-Hao Shao Kai-Wen Zhang Ming-Li Zou Ying-Ying Teng Fan Tian Meng-Nan Chen Wei-Wei Chen Zheng-Dong Yuan Jun-Jie Wu Feng-Lai Yuan 《Molecules (Basel, Switzerland)》2022,27(19)
Resveratrol (RSV) is a natural extract that has been extensively studied for its significant anti-inflammatory and antioxidant effects, which are closely associated with a variety of injurious diseases and even cosmetic medicine. In this review, we have researched and summarized the role of resveratrol and its different forms of action in wound healing, exploring its role and mechanisms in promoting wound healing through different modes of action such as hydrogels, fibrous scaffolds and parallel ratio medical devices with their anti-inflammatory, antioxidant, antibacterial and anti-ageing properties and functions in various cells that may play a role in wound healing. This will provide a direction for further understanding of the mechanism of action of resveratrol in wound healing for future research. 相似文献
974.
975.
论文针对奥氏体-马氏体双相材料,研究裂纹尖端区弥散分布的奥氏体颗粒在应变诱发时发生的相变对裂纹的屏蔽效应.鉴于实验中已发现的不同相变滞后对裂纹屏蔽效应的不同影响,研究通过在裂纹尖端区不同位置嵌入相变颗粒,考虑到裂纹尖端区应力应变场的奇异分布及其诱发的相变,将裂纹尖端区相变滞后问题转化为相变颗粒在裂纹尖端区的位置问题.计及奥氏体-马氏体相变的体积膨胀效应进行了平面应力裂纹问题数值模拟,得到了单个相变夹杂对裂纹屏蔽效应的影响规律.结果表明:裂纹尖端区相变夹杂的位置对裂纹的屏蔽效应在距裂尖2倍夹杂直径以内影响极大,且以裂尖86度方向为界.其影响规律与McMeeking和Evans理论预言的60度方向不同. 相似文献
976.
北京市作为中国政治中心和京津冀特大型城市,近40年来城市化进程迅速,大气颗粒物和尘埃粒子污染问题较为突出,发挥绿色空间滞尘功能具有重要现实意义。将高光谱技术与遥感技术相结合,反演了市域尺度绿色空间滞尘分布。以北京市区绿色空间常见植被大叶黄杨(Euonymus japonicus)为研究对象,通过室外采样与室内试验获取叶片样本的滞尘量、光谱反射率和叶面积等数据,比较叶片滞尘前后的原始光谱曲线和反射率一阶导数特征,分析不同滞尘量对光谱反射率的影响,探究对叶片滞尘量高度敏感的波段。利用光谱响应函数将地面采集的窄波段光谱反射率数据分别转化遥感卫星的宽波段光谱反射率数据,建立对应卫星波段植被指数比值与滞尘量的回归模型,选取拟合效果最好的回归模型作为滞尘反演模型。结合GF-2影像所提取北京市区绿色空间范围,采用滞尘反演模型获取北京市区绿色空间滞尘分布。进而插值得到北京市区尘埃污染分布,采用空间自相关模型检验其空间聚集特性。结果表明:740~1 870 nm波段,滞尘后光谱反射率明显低于滞尘前反射率,滞尘对红边、黄边、蓝边位置没有明显影响,对“红边幅值”和“红边面积”影响较明显,利用Sentinel... 相似文献
977.
The dual-interference fiber optical gyroscope (DIFOG) is a novel gyroscope that makes use of both birefringent axes in a polarization maintained fiber to generate two Sagnac interferometers. The Sagnac effect is doubled in the DIFOG, resulting in the same precision for a smaller fiber coil and shorter fiber, so it has some potential applications in miniaturized and low-cost situations. The mechanism of polarization nonreciprocity (PNR) in the DIFOG is investigated and the influence of PNR is analyzed theoretically. Simulation results based on the theoretical analysis indicate that PNR error causes the bias of interference signals and the output of the DIFOG to vary with the inherent nonreciprocal phase that arises from the optical configuration. The experiment verifies the theoretical and simulation results. 相似文献
978.
979.
Chemical fingerprint and simultaneous determination of alkaloids and flavonoids in aerial parts of genus Peganum indigenous to China based on HPLC‐UV: application of analysis on secondary metabolites accumulation
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Wei Liu Min Xuan Lei Zhang Xin Zhao Meng Shan Yan Li Liang Teng Zhengtao Wang Changhong Wang 《Biomedical chromatography : BMC》2014,28(12):1763-1773
The aerial parts of genus Peganum are officially used in traditional Chinese medicine. The paper aims to establish a high‐performance liquid chromatography (HPLC) method for fingerprint analysis and simultaneous determination of three alkaloids and two flavonoids in aerial parts of genus Peganum, and to analyze accumulative difference of secondary metabolites in inter‐species, individuals of plants, inter‐/intra‐population and from different growing seasons. HPLC analysis was performed on a C18 column with gradient elution using 0.1% trifloroacetic acid and acetonitrile as mobile phase and detected at 265 nm, by conventional methodology validation. For fingerprint analysis, the RSDs of relative retention time and relative peak area of the characteristic peaks were within 0.07–0.78 and 0.94–9.09%, respectively. For simultaneous determination of vasicine, harmaline, harmine, deacetylpeganetin and peganetin, all calibration curves showed good linearity (r > 0.9990) within the test range. The relative standard deviations of precision, repeatability and stability test did not exceed 2.37, 2.68 and 2.67%, respectively. The average recoveries for the five analytes were between 96.47 and 101.20%. HPLC fingerprints play a minor role in authenticating and differentiating the herbs of different species of genus Peganum. However, the secondary metabolites levels of alkaloids and flavonoids in aerial parts of genus Peganum rely on species‐, habitat‐, and growth season‐dependent accumulation. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
980.
Xiaoxu Teng Mingyu Tian Jinwen Zhang Lijun Tang Junna Xin 《Tetrahedron letters》2018,59(29):2804-2808
A new fluorescent probe (TCF-AC) that contains 2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran (TCF) skeleton has been developed. Probe TCF-AC exhibits highly selective and sensitive detection toward Pd0 in EtOH/H2O (1:1, v/v, PBS 20?mM, pH?=?7.4) solution with fluorescence “turn on” and colorimetric changes. The Pd0 detection by TCF-AC holds some advantages including good anti-interference ability, a relative large Stokes shift (>100?nm), and a low detection limit (7.05?×?10?7?M). Cell imaging studies demonstrate that TCF-AC is applicable to detect Pd0 in living HeLa cells. 相似文献