Polarization-Sensitive Spectral Interferometric Optical Coherence Tomography for Human Skin Imaging

Polarization-sensitive spectral interferometric optical coherence tomography (PS-SI-OCT) is designed for imaging of the inner structure of a biological tissue with polarization properties corresponding to Müller matrix elements. With arbitrary polarization state of incident and reference light, the change of polarization state can be acquired, and the axial structure of the tissue is measured by single detection of the power spectrum, superposition of object and reference light. Using with this OCT system, a cross-sectional Müller matrix images of human skin can be observed.     

Carbon-13 NMR spectra of hydroxylated bile acid stereoisomers

Carbon-13 NMR signals were assigned for the complete set of the 26 theoretically possible isomers of methyl 5β-cholanates having one to three hydroxy groups at positions C-3, C-7 and/or C-12 in the nucleus. Substituent effects on the ¹³C NMR shielding data serving to characterize the position and configuration of the hydroxy groups are discussed.     

Physiochemical properties of phenobarbital solid dispersion with phosphatidylcholine

We prepared a phenobarbital (PB) solid dispersion (SD) with phosphatidylcholine (PC). PB was present in an amorphous state in SD if its mole fraction was under 0.75. An infrared (IR) spectra study suggested a hydrogen bond between NH in PB and phosphate in PC, with a ratio of about 1:1. When the mole fraction of PB was less than 0.50, differential scanning calorimetry (DSC) curves showed endothermic peaks at 57, 90 and 145 degrees C, and an exothermic peak at 60 degrees C. The IR spectrum and X-ray diffraction pattern changed after holding at 70 degrees C, so at this point it is considered that the metastable state of SD changed into a stable state, and extra energy was released. When the mole fraction of PB was high, PB also arranged near hydrophobic group because an endothermic peak was observed at 46-52 degrees C, which was lower than fully hydrated PC. PB is similar to indomethacin (IM) in molecular shape and to phenytoin (PHT) in chemical structure. Its DSC curve and IR spectra are similar to PHT, and the limit ratio of its amorphous state is the same as IM. It is considered that the chemical structure is an important factor in its interaction to PC, and also, the molecular shape is important to arrange into PC lattice.     

Experimental results on proton diffractive dissociation

Properties of proton diffractive dissociation have been investigated for four-prong final states in proton-proton reactions at 360 GeV/c, in particular forpp→ppπ ⁺π^? mπ ⁰(m=0,1,2). Mass distributions and decay angular distributions are given. The decay of the diffractive system is seen to be very anisotropic, and largep _T is suppressed at higher masses. It is found that the “pomeron” couples with a single valence quark of the incident proton, but indications for a diquark-pomeron coupling are also found. Similarities with fragmentation in lepton-hadron deep inelastic scattering are underlined.     

Synthesis of trichotomine,a blue pigment obtained from clerodendron trichotomum thunb

Synthesis of trichotomine, a blue pigment obtained from $\text{clerodendron}$$\text{trichotomum}$ thunb.     

Crystal and molecular structure of [N N′-(3,3′-dipropylamine)-bis(salicylideneaminato)monoacetate]cobalt(III) complex

The crystal and molecular structure of [N,N′-(3,3′-dipropylamine)bis(salicyclideneaminato)-monoacetate]cobalt(III) complex has been determined by a three-dimensional X-ray diffraction study. In the complex, the cobalt ion has an octahedral coordination environment with cis-geometry for the two salicyclideneaminato moieties. An oxygen atom of the acetate ion is coordinated to cobalt ion and another oxygen atom is hydrogen-bonded to the secondary amine nitrogen atom.     

A method for determining the relaxation spectrum from the decay curve of electric birefringence of macromolecular solutions

Summary A numerical method for determining the distribution function of relaxation times from the decay curve of electric birefringence in macromolecular solutions has been described. The distribution function is expanded in a series of appropriate functions, and the best values of the coefficients are determined by the method of least squares. An application of this method to poly-Lglutamic acid in methanol is presented. It is shown that the distribution of molecular lengths can be obtained from the relaxation spectrum in the case of helical polypeptides in solution.

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Zusammenfassung Es wird eine numerische Methode beschrieben, die die Relaxationszeit-Verteilungsfunktion aus der Abklingkurve der elektrischen Doppelbrechung bei makromolekularen Lösungen zu bestimmen erlaubt. Die Verteilungsfunktion wird in eine Reihe geeigneter Funktionen entwickelt und die besten Werte der Koeffizienten werden nach der Methode der kleinsten Quadrate bestimmt. Eine Anwendung dieser Methode zur Poly-L-glutaminsäure in Methanol-Lösung wird exemplifiziert. Es zeigt sich, daß die Verteilung von Moleküllängen im Falle helicaler Polypeptide aus dem Relaxationsspektrum gewonnen wird.

     

Synthesis of thromboxane A2 analogs—1 : (±)-Dimethanothromboxane A2

The stable thromboxane A₂ analog (±)-dimethanothromboxane A₂ 1 was synthesized from bicyclo[3.1.1]heptane 2 via the tricyclic compound 4.