Synthesis and DNA binding studies of Ni(II), Co(II), Cu(II) and Zn(II) metal complexes of N1,N5-bis[pyridine-2-methylene]-thiocarbohydrazone Schiff-base ligand

The thiocarbohydrazone Schiff-base ligand with a nitrogen and sulphur donor was synthesized through condensation of pyridine-2-carbaldehyde and thiocarbohydrazide. Schiff-base ligands have the ability to conjugate with metal salts. A series of metal complexes with a general formula [MCl2(H2L)]·nH2O (MNi, Co, Cu and Zn) were synthesized by forming complexes of the N1,N5-bis[pyridine-2-methylene]-thiocarbohydrazone (H2L) Schiff-base ligand. These metal complexes and ligand were characterized by using ultraviolet-visible (UV-Vis), Fourier Transform Infrared (FT-IR), 1H and 13C NMR spectroscopy and mass spectroscopy, physicochemical characterization, CHNS and conductivity. The biological activity of the synthesized ligand was investigated by using Escherichia coli DNA as target. The DNA interaction of the synthesized ligand and complexes on E. coli plasmid DNA was investigated in the aqueous medium by UV-Vis spectroscopy and the binding constant (Kb) was calculated. The DNA binding studies showed that the metal complexes had an improved interaction due to trans-geometrical isomers of the complexes than ligand isomers in cis-positions.     

Use of graphite oxide and graphene oxide as catalysts in the synthesis of dipyrromethane and calix[4]pyrrole

Graphite oxide and graphene oxides have been used as solid catalysts for the synthesis of 5,5-dialkyldipyrromethanes and calix[4]pyrroles in organic and aqueous solutions at room temperature.     

An efficient one-pot synthesis of carbazates and dithiocarbazates through the corresponding alcohols using Mitsunobu��s reagent

A novel Mitsunobu-based protocol has been developed for the synthesis of carbazates and dithiocarbazates through the variety of corresponding primary, secondary and tertiary alcohols and various kinds of substituted hydrazines using Mitsunobu??s reagent and CO₂/CS₂ system, in good to excellent yields.     

Molecular orbital study of excited state geometry of substituted benzenes

The liquid-like structure of a polystyrene latex solution of particle size 109 nm and its dependence on the ionic strength of added sodium chloride is investigated via the static light scattering structure factor S(Q). The experimental S(Q)s are compared with structure factors derived in the rescaled mean spherical approximation (RMSA) of Hansen and Hayter. After adjustment of the macromolecular charge Z _M such that the neat (salt free) latex solution is best represented by the RMSA, the experimental structure factors obtained after addition of salt can adequately be accounted for in terms of the RMSA by merely readjusting the ionic strength in the calculations. Our investigation indicates that the RMSA and the underlying screened Coulomb potential are suited for a detailed simulation of the structure and structural changes due to a variation of the ionic strength of liquid-like ordered solutions.     

Phase diagram of two-dimensional binary Yukawa mixtures

We have used Ramakrishnan–Yussouff (RY) density functional theory (DFT) to explore the topology of the phase diagram of two-component charge stabilised colloidal suspensions confined to a two-dimensional plane. The particles of the system interact via purely repulsive soft core Yukawa potential. Pair correlation functions (PCFs) used as input informations in DFT were calculated by solving both the hypernetted chain (HNC) and Percus–Yevick (PY) integral equation theories. To test the relative performance of the HNC and PY theories in the context of phase transitions, we have also studied the corresponding one-component systems. We found that RY DFT with HNC PCFs does not stabilise solid in both the one- and two-component cases, whereas the PY theory does. By considering the freezing into the substitutionally disordered triangular solid, we found that the temperature-composition phase diagrams of the binary mixture are narrow spindles whose thickness depends on the symmetry of the mixture components and the value of the screening constant of the Yukawa potential. Although the phase diagram obtained by RY DFT with structural inputs calculated by the PY theory is found to be shifted to higher temperature region in the temperature-composition plane, however, it captures qualitatively all the essential features of the phase diagram. Our results are in principle verifiable through computer simulations and experiments.     

Stopping power measurements of Si in polycarbonate detectors

The rate of energy loss of the impinging ion as it passes through succeeding layers of the target material gives information regarding the nature of the material and helps to calculate the range of the ions in a thick target in which the ions are stopped. In the present work, the range of 118 MeV ²⁸Si was measured in different types of polycarbonates, viz. Makrofol-N, Makrofol-G and Makrofol-KG, using the nuclear track technique. Polyallyldiglycol carbonate (PADC) was used as the backing detector. The experimental values of range and energy-loss rate are compared with the theoretical values obtained from different computer codes, viz. BENTON, HUBERT, RANGE, TRIM’98 and SRIM’03.     

Spontaneous emission in longitudinal wiggler and solenoidal magnetic field

Summary In this paper we study the spectral brightness of the radiation emitted by electrons moving in longitudinal wiggler and solenoidal magnetic field. The analysis is based on the evaluation of the Lienard-Wiechert potential retaining the condition of far-field limit. Some features of a longitudinal wiggler are presented and compared with the results relevant to the brightness of the helical wiggler and the solenoidal magnetic field employed in gyrotron-type devices.     

Reverse saturable absorption and optical limiting in indanthrone dyes

Fluence dependence of transmission in three dyes, viz. indanthrone, dichloroindanthrone and violanthrone, is reported at 532 nm as well as at 1.06 µm. These dyes show optical limiting at both these wavelengths for nanosecond pulses. The limiting is due to the combined effect of reverse saturable absorption from the triplet state and thermal defocussing in the dye solutions.     

Geometrization of magnetohydrodynamic equations via lie groups

The equations of magnetohydrodynamics of a perfect fluid are classified with respect to the Coriolis parameter, and all essentially different solutions of rank one are indicated. The geometry of streamlines is discussed.     

Kinetics and mechanism of oxidation of 1,4-butanediol by chromium(VI) in acid perchlorate medium

Summary The kinetics of oxidation of 1,4-butanediol by chromium(VI) was studied in acid perchlorate medium and the oxidation product of the diol was identified as 4-hydroxybutanal. The kinetic rate law observed accounted for the complex dependence of the hydrogen ion k=(k₂K₁[H+]+k₃K₁K₂[H+]²)/(1+K₁[H]+) where k is the observed second-order rate constant.