Zinc-Mediated Facile and Efficient Chemoselective S-Alkylation of 5-Aryl-1,3,4-oxadiazole-2-thiols in the Absence of Base

Zinc-mediated facile and efficient chemoselective S-alkylation of 5-aryl 1,3,4-oxadiazole-2-thiols in the presence of a catalytic amount of tetra butyl ammonium iodide was described. The reaction was performed under neutral conditions. The chemoselectivity of the alkylation was confirmed by NMR spectroscopy and x-ray crystallography.     

Warm-intermediate inflationary universe model in braneworld cosmologies

Warm-intermediate inflationary universe models in the context of braneworld cosmologies are studied. This study is done in the weak and strong dissipative regimes. We find that the scalar potentials and dissipation coefficients in terms of the scalar field evolve as type-power-law and powers of logarithms, respectively. General conditions required for these models to be realizable are derived and discussed. We also study the scalar and tensor perturbations for each regime. We use recent astronomical observations to constrain the parameters appearing in the braneworld models.     

Dynamic multiscaling in two-dimensional fluid turbulence

We obtain, by extensive direct numerical simulations, time-dependent and equal-time structure functions for the vorticity, in both quasi-Lagrangian and Eulerian frames, for the direct-cascade regime in two-dimensional fluid turbulence with air-drag-induced friction. We show that different ways of extracting time scales from these time-dependent structure functions lead to different dynamic-multiscaling exponents, which are related to equal-time multiscaling exponents by different classes of bridge relations; for a representative value of the friction we verify that, given our error bars, these bridge relations hold.     

On-Surface Synthesis and Characterization of Acene-Based Nanoribbons Incorporating Four-Membered Rings

A bottom up method for the synthesis of unique tetracene-based nanoribbons, which incorporate cyclobutadiene moieties as linkers between the acene segments, is reported. These structures were achieved through the formal [2+2] cycloaddition reaction of ortho-functionalized tetracene precursor monomers. The formation mechanism and the electronic and magnetic properties of these nanoribbons were comprehensively studied by means of a multitechnique approach. Ultra-high vacuum scanning tunneling microscopy showed the occurrence of metal-coordinated nanostructures at room temperature and their evolution into nanoribbons through formal [2+2] cycloaddition at 475 K. Frequency-shift non-contact atomic force microscopy images clearly proved the presence of bridging cyclobutadiene moieties upon covalent coupling of activated tetracene molecules. Insight into the electronic and vibrational properties of the so-formed ribbons was obtained by scanning tunneling microscopy, Raman spectroscopy, and theoretical calculations. Magnetic properties were addressed from a computational point of view, allowing us to propose promising candidates to magnetic acene-based ribbons incorporating four-membered rings. The reported findings will increase the understanding and availability of new graphene-based nanoribbons with high potential in future spintronics.     

Directing Group-Promoted Inert C−O Bond Activation Using Versatile Boronic Acid as a Coupling Agent

A simple Ni(cod)₂ and carbene mediated strategy facilitates the efficient catalytic cross-coupling of methoxyarenes with a variety of organoboron reagents. Directing groups facilitate the activation of inert C−O bonds in under-utilized aryl methyl ethers enabling their adaptation for C−C cross-coupling reactions as less toxic surrogates to the ubiquitous haloarenes. The method reported enables C−C cross-coupling with readily available and economical arylboronic acid reagents, which is unprecedented, and compares well with other organoboron reagents with similarly high reactivity. Extension to directing group assisted chemo-selective C−O bond cleavage, and further application towards the synthesis of novel bifunctionalized biaryls is reported. Key to the success of this protocol is the use of directing groups proximal to the reaction center to facilitate the activation of the inert C−OMe bond.     

Antibacterial activity of agave fructans against salmonella typhimurium

Abstract

The objective of this study was to evaluate the antimicrobial effect of Agave fructans against the Salmonella Typhimurium in “in vitro” experiments. The result of the antimicrobial activity was 263.89?±?0, 414.95?±?12.83, 494.54?±?13.88, 522.29?±?0, 580.41?±?14.92?AU for 10, 20, 30, 40 and 50% of Agave fructans (AF) respectively. In addition, there is a significant effect on the growth of the bacteria with all the percentages of AF evaluated (p?<?0.001, R2?=?0.859) with respect to the control. The growth rate of Salmonella with 25% AF was statistically significant compared to the control (?0.7353?±?0.586, 0.0079?±?0.002?D.O./h, respectively; p?>?0.01). Agave fructans could be an alternative to prevent the infections caused by Salmonella.     

Transcendental values of class group <Emphasis Type="Italic">L</Emphasis>-functions

Let K be an algebraic number field and f a complex-valued function on the ideal class group of K. Then, f extends in a natural way to the set of all non-zero ideals of the ring of integers of K and we can consider the Dirichlet series \({L(s,f) =\sum_{{\mathfrak a}} f({\mathfrak a}){\bf N}({\mathfrak a})^{-s}}\) which converges for \({{\mathfrak R}(s) >1 }\). After extending this function to \({{\mathfrak R}(s)=1}\), and in the case that f does not contain the trivial character, we study the special value L(1, f) when f is algebraic valued and K is an imaginary quadratic field. Applying Kronecker’s limit formula and Baker’s theory of linear forms in logarithms, we derive a variety of results related to the transcendence of this special value.