A LOV2 Domain-Based Optogenetic Tool to Control Protein Degradation and Cellular Function

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Highlights? Optogenetic tool to control the stability of soluble and membrane proteins ? Engineered using the LOV2 domain and a murine ornithine decarboxylase-like degron ? Creation of light-switchable, conditional mutants ? Graded response to very low blue light intensities allows yeast photography     

Carbon Dynamics on the Molybdenum Carbide Surface during Catalytic Propane Dehydrogenation

The effect of the gas‐phase chemical potential on surface chemistry and reactivity of molybdenum carbide has been investigated in catalytic reactions of propane in oxidizing and reducing reactant mixtures by adding H₂, O₂, H₂O, and CO₂ to a C₃H₈/N₂ feed. The balance between surface oxidation state, phase stability, carbon deposition, and the complex reaction network involving dehydrogenation reactions, hydrogenolysis, metathesis, water‐gas shift reaction, hydrogenation, and steam reforming is discussed. Raman spectroscopy and a surface‐sensitive study by means of in situ X‐ray photoelectron spectroscopy evidence that the dynamic formation of surface carbon species under a reducing atmosphere strongly shifts the product spectrum to the C₃‐alkene at the expense of hydrogenolysis products. A similar response of selectivity, which is accompanied by a boost of activity, is observed by tuning the oxidation state of Mo in the presence of mild oxidants, such as H₂O and CO₂, in the feed as well as by V doping. The results obtained allow us to draw a picture of the active catalyst surface and to propose a structure–activity correlation as a map for catalyst optimization.     

A Raman technique applicable for the analysis of the working principle of promoters and inhibitors of gas hydrate formation

We report a Raman technique applicable for the in situ analysis of the development of hydrogen bonds in the liquid water‐rich phase just before the onset of gas hydrate formation. Herewith, the phase transition as well as the working principle of hydrate formation inhibitors and promoters can be analyzed. © 2015 The Authors. Journal of Raman Spectroscopy published by John Wiley & Sons Ltd.     

Magnetic ground state of coupled edge-sharing CuO2 spin chains

By means of density functional theory, we investigate the magnetic ground state of edge-sharing CuO2 spin chains, as found in the (La,Ca,Sr)14Cu24O41 system, for instance. Our data rely on spin-polarized electronic structure calculations including on-site interaction [local density approximation plus the multiorbital mean-field Hubbard model (LDA+U)] and an effective model for the interchain coupling. Strong doping dependence of the magnetic order is characteristic for edge-sharing CuO2 spin chains. We determine the ground state magnetic structure as function of the spin-chain filling and quantify the competing exchange interactions.     

Sideband transitions and two-tone spectroscopy of a superconducting qubit strongly coupled to an on-chip cavity

Sideband transitions are spectroscopically probed in a system consisting of a Cooper pair box strongly but nonresonantly coupled to a superconducting transmission line resonator. When the Cooper pair box is operated at the optimal charge bias point, the symmetry of the Hamiltonian requires a two-photon process to access sidebands. The observed large dispersive ac-Stark shifts in the sideband transitions induced by the strong nonresonant drives agree well with our theoretical predictions. Sideband transitions are important in realizing qubit-photon and qubit-qubit entanglement in the circuit quantum electrodynamics architecture for quantum information processing.