全文获取类型
收费全文 | 3753篇 |
免费 | 104篇 |
国内免费 | 10篇 |
专业分类
化学 | 2161篇 |
晶体学 | 56篇 |
力学 | 57篇 |
数学 | 606篇 |
物理学 | 987篇 |
出版年
2020年 | 43篇 |
2019年 | 51篇 |
2018年 | 39篇 |
2017年 | 32篇 |
2016年 | 73篇 |
2015年 | 67篇 |
2014年 | 69篇 |
2013年 | 139篇 |
2012年 | 131篇 |
2011年 | 136篇 |
2010年 | 109篇 |
2009年 | 87篇 |
2008年 | 127篇 |
2007年 | 105篇 |
2006年 | 109篇 |
2005年 | 110篇 |
2004年 | 105篇 |
2003年 | 76篇 |
2002年 | 94篇 |
2001年 | 67篇 |
2000年 | 95篇 |
1999年 | 77篇 |
1998年 | 56篇 |
1997年 | 61篇 |
1996年 | 60篇 |
1995年 | 53篇 |
1994年 | 78篇 |
1993年 | 75篇 |
1992年 | 62篇 |
1991年 | 55篇 |
1990年 | 57篇 |
1989年 | 42篇 |
1988年 | 40篇 |
1987年 | 46篇 |
1986年 | 60篇 |
1985年 | 62篇 |
1984年 | 51篇 |
1983年 | 55篇 |
1982年 | 48篇 |
1981年 | 43篇 |
1980年 | 65篇 |
1979年 | 44篇 |
1978年 | 56篇 |
1977年 | 58篇 |
1976年 | 52篇 |
1975年 | 57篇 |
1974年 | 44篇 |
1973年 | 51篇 |
1972年 | 34篇 |
1971年 | 32篇 |
排序方式: 共有3867条查询结果,搜索用时 15 毫秒
51.
Schneider MJ Vazquez-Moreno L Bermudez-Almada Mdel C Guardado RB Ortega-Nieblas M 《Journal of AOAC International》2005,88(4):1160-1166
An efficient multiresidue method for analysis of fluoroquinolones in shrimp has been developed in which quantitation by fluorescence and confirmation by Multiple Stage Mass Spectrometry (MS) is achieved simultaneously. In this method, shrimp tissue is extracted with ammoniacal acetonitrile and the extract is defatted and then evaporated. After dissolution in basic phosphate buffer, fluoroquinolones in the extract are separated by liquid chromatography and quantitated, taking advantage of their intense fluorescence. Eluate from the fluorescence detector enters the MS, which allows for confirmation by monitoring ratios of 2 prominent product ions in the MS3 or MS2 spectrum. Using this method, 8 fluoroquinolones have been analyzed in shrimp samples fortified at 10, 25, 50, or 100 ppb levels. Recoveries for desethyleneciprofloxacin, norfloxacin, ciprofloxacin, danofloxacin, enrofloxacin, orbifloxacin, sarafloxacin, and difloxacin ranged from 75 to 92%, with relative standard deviation values of <6%. The limits of quantitation ranged from 0.1 to 1 ng/g. Enrofloxacin and ciprofloxacin were also successfully determined in enrofloxacin-incurred shrimp using this method. 相似文献
52.
Treatment of [CrCl3(THF)3] with slightly more than 1 equiv of Li3(N3N) [(N3N)(3-) = ((Me3SiNCH2CH2)3N)(3-)] affords the triamidoamine complex [Cr(N3N)] (1) in 75% yield. 1 is oxidized by PhICl2, CuCl2, or AgCl to give the chromium(IV) complex [Cr(N3N)Cl] (2) in moderate yields. Alternatively, complex 2 is obtained directly from [CrCl3(THF)3] in 50% yield after treatment with 0.5 equiv of Li3(N3N). Both compounds are high-spin complexes bearing three and two unpaired electrons, respectively. Their molecular structures are described revealing a trigonal monopyramidal and trigonal bipyramidal coordination geometry of the chromium center, respectively. 相似文献
53.
The preparation of η-C3H5V(CO)5 from allyl chloride and sodium hexacarbonylvanadate (–I) is reported. Composition, IR and NMR spectra are in accordance with a π-bonded C3H5-moiety; the preparation has been extended to give complexes with substituted allyl groups. Furthermore (1-3-η-2-butenyl)pentacarbonylvanadium can be obtained by the addition of butadiene to HV (CO)6. 相似文献
54.
Skehel JM Schneider K Murphy N Graham A Benson GM Cutler P Camilleri P 《Electrophoresis》2000,21(12):2540-2545
Apolipoprotein E (ApoE) plays an important role in cholesterol and triglyceride metabolism, being one of the major structural components of chylomicrons and very low density lipoprotein (VLDL) remnants. ApoE functions as a ligand in the receptor-mediated uptake of these remnants from the blood by the liver. A variant form of ApoE, apolipoprotein E*3-Leiden, shows reduced affinity for the low density lipoprotein (LDL) receptor, and results in the dominant expression of type III hyperlipoproteinemia. Two-dimensional electrophoresis (2-DE) has been used to characterise protein expression in serum samples from control and transgenic mice expressing the human ApoE*3-Leiden mutation, fed a cholesterol-rich diet, and transgenic mice fed a normal diet. For the identification of proteins, single silver-stained spots were excised from the 2-DE gels and subjected to in-gel enzymatic digestion. Extracted peptides were analysed by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS). This proteomic approach has enabled the ApoE*3-Leiden variant to be positioned in a 2-DE separation of serum proteins, and has identified changes in the expression of haptoglobin, indicating that this protein may provide a marker for the potential onset of atherosclerosis. 相似文献
55.
The first part of the paper deals with a critical discussion of the methodical basis of essential work of fracture (EWF) concept with respect to the specimen geometry (especially the notch depth) and application to polymers. In the second part, an in situ testing device, which combines a tensile testing machine with an optical strain-field measuring system, has successfully demonstrated possibility of characterization of fracture behaviour of polystyrene-polybutadiene block copolymers and block copolymer/homopolymer blends as examples of nanostructured polymer materials. It has been shown that knowledge of the time evolution of the strain field close to the crack tips leads to a simple verification of the basic precondition for the applicability of the EWF concept, the precondition “plastic zone coalescence-before-stable crack propagation”. 相似文献
56.
A single-crystal neutron diffraction analysis of the cluster complex [H(4)Co(4)(C(5)Me(4)Et)(4)] was carried out on the new quasi-Laue diffractometer VIVALDI at the Institut Laue-Langevin. The structure consists of four face-bridging hydrides attached to a tetrahedral cobalt metal core. Average distances and angles in the core of the molecule are as follows: Co-Co = 2.571(8), Co-C = 2.158(6), Co-H = 1.749(7), H.H = 2.366(9) A; Co-H-Co = 94.6(3), H-Co-H = 85.1(3) degrees. The hydride ligands are located off the Co-Co-Co planes by an average distance of 0.923(8) A. It is suggested that the dimensions of the HCo(3) fragments found in this molecule provide reasonable estimates for analogous distances and angles associated with chemisorbed H atoms situated on the 3-fold hollows of a cobalt surface. Crystallographic details: space group P2(1)/a (monoclinic); a = 21.979(2), b = 10.924(1), c = 34.406(2) A; beta = 90.81(1) degrees; Z = 8. Final agreement factor: R(F) = 0.099 for 3779 reflections [I > 2sigma(I)] collected at 20 K. 相似文献
57.
Summary A new, rapid, and precise liquid chromatographic method has been developed for simultaneous identification and quantification
of amphetamine,N-methyl-3,4-methylenedioxymetamphetamine,N-ethyl-3,4-methylenedioxymetamphetamine, andN-methyl-1-(3,4-methyl-enedioxyphenyl)-2-butanamine in the presence of other constituents. The compounds were separated on
a monolithic column with a gradient prepared from acetonitrile and 20mm monobasic potassium buffer at a flow rate of 1.5 mL min−1. Quantitation was performed with metoclopramide as internal standard. Use of different flow rates was investigated and enabled
reduction of the separation time from 11 to 3.5 min for seven substances. The method was then applied to ten seized tablets
to identify and quantify their active ingredients. 相似文献
58.
Schneider BB Douglas DJ Chen DD 《Rapid communications in mass spectrometry : RCM》2002,16(20):1982-1990
A multiple sprayer electrospray ion source for high-throughput analysis is described. The ion source is comprised of multiple electrospray capillaries, each with an ion lens located near the tip. The electric potentials applied to the ion lenses are used to control the sprayers. The use of ion lenses eliminates the need for mechanical blocking devices to selectively enable or disable the sprayers, and results in a less expensive and more reliable set-up. Sprayers can be enabled or disabled within approximately 50-250 ms when the lens potentials are controlled manually. For simultaneous operation of multiple electrospray capillaries, it is advantageous to orient the capillaries so that the spray from each passes directly in front of the entrance aperture of the mass spectrometer. 相似文献
59.
C. N. Cascaval I. A. Schneider I. C. Poinescu 《Journal of polymer science. Part A, Polymer chemistry》1975,13(10):2259-2268
Pyrolysis, in combination with gas-chromatography technique, was used in the determination of the structure and study of the thermal degradation mechanism of the condensation polymers obtained by Friedel-Crafts reactions of poly(vinyl chloride) with benzene, toluene, and naphthalene. The separation of the pyrolysis products was made using a column packed with chromosorb W (80–100 mesh) coated with 15% silicone SE-52. The identification of the pyrolysis products resulted as a consequence of the thermal decomposition of condensation polymers and their semiquantitative estimation led to the final conclusion that the initial normal chlorine substitution in the macromolecular chain of poly(vinyl chloride) is followed by an important intramolecular cyclization reaction yielding 1,3-methyleneindan units. 相似文献
60.
The structures of the stable conformers of N-methyjpropionamide and N-methyliso-butyroamide in CCl4, solution were determined by a combination of IR spectroscopy and NMR spectroscopy with lanthanide shift reagents. N-methyl-propionamide was found to exist in the form of two rotational isomers, 1 and 2, with the ethyl group twisted out of the plane of the amide bond by the angles Ψ = 140 and 20°, respectively. For these two conformers, the enthalpy difference is ΔH = 2.13 ± 0.08 kcal mole?1 and the entropy difference ΔS = 7.81 ± 0.55 cal mole?1 grad?1. N-methylisobutyroamide exists in a single form, with the two C-methyl group positions very close to those found in the two isomers of N-methylpropionamide. 相似文献