Isolation of 2-Chloro-5-methylpyridine from its Isomer 2-Chloro-3-methylpyridine by Formation of its Copper(II) Complex

2-Chloro-5-methylpyridine is an important intermediate for the preparation of biological active compounds, especially insecticides1, e.g. imidacloprid2, and is usually manufac- tured from 3-methylpyridine N-oxide. However, the manufacturing process also forms the by-products: 3-methylpyridine and its isomer 2-chloro-3-methylpyridine3. The pro- perties of the isomers are similar, it is difficult to separate by ordinary methods, such as distillation. Scheme 1 79.4%13.6%5.2%NClCH3NCH3ClNC…     

Metabolites of A Novel Antibiotic Bitespiramycin in Rat Urine and Bile

A sensitive analytical method to identify active metabolites of bitespiramycin in rat urine and bile was developed by liquid chromatography-electrospray ionization tandem mass spectrometry(LC/ESI-MS^n).Bitespiramycin and its major active metabolites in rat urine and bile were isolated and identified as M1 serial(spiramycin Ⅰ，Ⅱ，Ⅲ),M2 serial(platenomycin A1,josamycin and leucomycin A1) and M3 serial(deisovalerylplatenomycin A1,deisovaleryljosamycin,deisovalerylleucomycin A1).     

Synthesis and Photochemical Properties of a New Substituted Phenol Covalently Linked to Ruthenium （Ⅱ） Tris-bipyridine Containing Four Ester Groups as Sensitizer

As photosensitizer for solar cell, a new ruthenium (Ⅱ) complex with four ester groups had been synthesized, in which a phenol substituted by {[(2-hydroxy-5-tert-butylbenzyl)(pyridyl-2-methyl)amino]methyl} is covalently linked to ruthenium (Ⅱ) tris-bipyridine. The structures of the new compounds were confirmed by NMR and ESI-MS spectra. The electrochemical and photochemical properties were also studied.     

Regioselective 1,4-trifluoromethylation of α,β-enones using ‘protect-in-situ’ methodology

In a convenient and efficient procedure, the nucleophilic 1,4-trifluoromethylation of several α,β-enones using (trifluoromethyl)trimethylsilane was achieved. The high regioselectivity of the reaction has been reached by blocking the carbonyl moiety of the electrophile with a bulky aluminum-centered Lewis acid.     

单调全局最优化问题的凸化外逼近算法

单调优化是指目标函数与约束函数均为单调函数的全局优化问题．本文提出一种新的凸化变换方法把单调函数化为凸函数，进而把单调优化问题化为等价的凸极大或凹极小问题，然后采用Hoffman的外逼近方法来求得问题的全局最优解．我们把这种凸化方法同Tuy的Polyblock外逼近方法作了比较，通过数值比较可以看出本文提出的凸化的方法在收敛速度上明显优于Polyblock方法．     

模拟纳米晶体原子分布及X射线散射理论图案

通过分子动力学方法模拟纳米晶体（1—3nm）的结构．利用模拟的结果，进行了X射线衍射及径向分布函数的模拟计算．结果表明：纳米晶体晶界呈短程有序，界面原子间距分布很宽；随着晶粒尺寸的减小，晶粒的畸变越大，原子体积常数也明显增大 关键词：     

Inclusive semileptonic decays of B mesons

The probability of inclusive semileptonic decay of B mesons is calculated in the constituent-quark model. A compact formula is obtained for the differential decay width of a B meson in terms of the corresponding decay width of a free b quark and the wave function of the internal motion of the quarks in the B meson. Numerical values of semileptonic-decay widths are obtained for a series of models of the wave function. Pis’ma Zh. éksp. Teor. Fiz. 65, No. 10, 734–737 (25 May 1997)     

Nearest-neighbor two-point correlation function of the Z-invariant eight-vertex model

The nearest-neighbor two-point correlation function of the Z-invariant inhomogeneous eight-vertex model in the thermodynamic limit is computed using the free-field representation. Pis’ma Zh. éksp. Teor. Fiz. 68, No. 3, 243–247 (10 August 1998) Published in English in the original Russian journal. Edited by Steve Torstveit.     

Cauchy problem and averaging in Fock space

We investigate a Cauchy problem in the Fock space for a system consisting of a two-level atom, a quantum field, and a classical field. A solution estimate is obtained for the Cauchy problem with initial data from a special class. This class is invariant with respect to the dynamic semigroup of the system. We propose an averaging method for solving the Cauchy problem in the case where the Hamiltonian parameters differ greatly in the order of magnitude. An estimate of the averaging error is obtained. Translated from Teoreticheskaya i Matematicheskaya Fizika, Vol. 117, No. 1, pp. 92–106, October, 1998.