基于一种新型有机聚合物整体柱的毛细管电色谱技术用于利尿剂的分离与检测

采用自制的新型有机聚1-十六碳烯-三羟甲基丙烷三甲基丙烯酸酯［poly(1-hexadecene-co-TMPTMA)］整体柱,建立了一种同时分离检测6种利尿剂(氯噻酮、氢氯噻嗪、美托拉宗、吲哒帕胺、坎利酮和螺内酯)的毛细管电色谱(CEC)新方法,并成功应用于志愿者实际尿样的分析测定。在最佳实验条件下,6种利尿剂包含2种中性物质(坎利酮和螺内酯)和2种同分异构体(美托拉宗和吲哒帕胺)在11.0 min内得到基线分离,柱效分别达到218000、176000、143000、121000、108000、103000 塔板/m。6种利尿剂在1.15～86.0 μg/mL范围内呈良好的线性关系,相关系数R2 ≥0.990 8,检出限(LOD)在0.35～0.65 μg/mL范围内,回收率为81.9%~105%,相对标准偏差(RSD)小于4.7%。结果表明,实验所建立的基于poly(1-hexadecene-co-TMPTMA)整体柱的CEC方法,具有良好的重复性和稳定性,能够实现对多种利尿剂的同时分离检测。该方法已成功应用于来自志愿者实际尿样的分析,该方法可以用于利尿剂类药物的初筛。     

基于N-十二酰基-l-脯氨酸为载体的对映异构PVC膜选择性电极的研制

合成了手性物质N-十二酰基-l-脯氨酸(N-DDO-l-Pro)(脯氨酸, Pro), 作为PVC膜电极的载体, 在PVC膜表面与被测试液中Cu(II)与脯氨酸形成的配合物[Cu(II)(l-Pro)₂]或[Cu(II)(d-Pro)₂]进行配体交换, 形成[(l-Pro)Cu(II) (N-DDO-l-Pro)]或[(d-Pro)Cu(II)(N-DDO-l-Pro)]配合物. 由于生成的配合物热力学稳定性不同, 电极能优先响应l-Pro, 线性范围10^－4～10^―1 mol•L^－1, 斜率57 mV•dec^－1, 检测限3.89×10^－5 mol•L^－1. 电极能够对脯氨酸进行手性检测, 其对映选择性系数lg为－3.19.     

功能梯度材料瞬态热传导问题的降维精细积分法

针对功能梯度材料(FGMs)的二维瞬态热传导问题,提出了一种有效的降维精细积分法。通过空间坐标的分步离散,将原二维问题的精细积分转化为一系列一维问题的精细积分,解决了直接精细积分算法所面临的传递矩阵 规模过大的问题,从而大幅度降低了计算量和存储量。算例表明了本文方法的有效性。     

64通道一维位置灵敏电流分布探测器及其数据获取系统

针对高流强粒子束与绝缘毛细管相互作用的特点, 设计制作了一套64通道一维位置灵敏电流分布探测器及其配套的数据获取系统, 该探测器可分辨最小直径为1 mm的束斑, 通过数据获取系统可实现可视化自动数据采集。 用2 nA和200—2000 eV电子对探测器进行了定标, 并用10 μA和2000 eV的电子束穿越锥形毛细管后的出射电子, 对探测器及数据获取系统进行测试, 获得了出射粒子的位置分布谱及能量信息。 A 64 channel position sensitive current distribution detector with 1 mm position resolution was developed, while the data acquisition system is based on the LabVIEW software. The test result obtained by using a 2 nA, 200—2000 eV electron beam deflecting by different voltages and the position spectra of 10 μA, 2000 eV electrons transmitted through a glass capillary was measured. The result indicated that the detector can be used to detect the charged particles with strong beam current through the capillary.     

Dispersion characteristics of two-dimensional unmagnetized dielectric plasma photonic crystal

This paper studies dispersion characteristics of the transverse magnetic (TM) mode for two-dimensional unmagnetized dielectric plasma photonic crystal by a modified plane wave method. First, the cutoff behaviour is made clear by using the Maxwell--Garnett effective medium theory, and the influences of dielectric filling factor and dielectric constant on effective plasma frequency are analysed. Moreover, the occurence of large gaps in dielectric plasma photonic crystal is demonstrated by comparing the skin depth with the lattice constant, and the influence of plasma frequency on the first three gaps is also studied. Finally, by using the particle-in-cell simulation method, a transmission curve in the \Gamma -X direction is obtained in dielectric plasma photonic crystal, which is in accordance with the dispersion curves calculated by the modified plane wave method, and the large gap between the transmission points of 27~GHz and 47~GHz is explained by comparing the electric field patterns in particle-in-cell simulation.     

Integration of B-spline geometry and ANCF finite element analysis

The goal of this investigation is to introduce a new computer procedure for the integration of B-spline geometry and the absolute nodal coordinate formulation (ANCF) finite element analysis. The procedure is based on developing a linear transformation that can be used to transform systematically the B-spline representation to an ANCF finite element mesh preserving the same geometry and the same degree of continuity. Such a linear transformation that relates the B-spline control points and the finite element position and gradient coordinates will facilitate the integration of computer aided design and analysis (ICADA). While ANCF finite elements automatically ensure the continuity of the position and gradient vectors at the nodal points, the B-spline representation allows for imposing a higher degree of continuity by decreasing the knot multiplicity. As shown in this investigation, a higher degree of continuity can be systematically achieved using ANCF finite elements by imposing linear algebraic constraint equations that can be used to eliminate nodal variables. The analysis presented in this study shows that continuity of the curvature vector and its derivative which corresponds in the cubic B-spline representation to zero knot multiplicity can be systematically achieved using ANCF finite elements. In this special case, as the knot multiplicity reduces to zero, the recurrence B-spline formula causes two segments to automatically blend together forming one cubic segment defined on a larger domain. Similarly in this special case, the algebraic constraint equations required for the C ³ continuity convert two ANCF cubic finite elements to one finite element, demonstrating the strong relationship between the B-spline representation and the ANCF finite element representation. For the same order of interpolation, higher degree of continuity at the finite element interface can lead to a coarser mesh and to a lower dimensional model. Using the B-spline/ANCF finite element transformation developed in this paper, the equations of motion of a finite element mesh that represents exactly the B-spline geometry can be developed. Because of the linearity of the transformation developed in this investigation, all the ANCF finite element desirable features are preserved; including the constant mass matrix that can be used to develop an optimum sparse matrix structure of the nonlinear multibody system dynamic equations.     

Optical switching based on the manipulation of microparticles in a colloidal liquid using strong scattering force

This paper demonstrates the realization of an optical switch by optically manipulating a large number of polystyrene spheres contained in a capillary.The strong scattering force exerted on polystyrene spheres with a large diameter of 4.3 μm is employed to realize the switching operation.A transparent window is opened for the signal light when the polystyrene spheres originally located at the beam centre are driven out of the beam region by the strong scattering force induced by the control light.The switching dynamics under different incident powers is investigated and compared with that observed in the optical switch based on the formation of optical matter.It is found that a large extinction ratio of ～ 30 dB and fast switching-on and switching-off times can be achieved in this type of switch.     

焊管的残余应力测试与研究

通过小孔法与分割法对φ272mm螺旋埋弧焊管和φ380mm对接焊管的残余应力测试,分析探讨了螺旋焊缝、环焊缝以及焊缝热影响区的残余应力分布。研究结果表明,不同工艺焊接成型的圆管,其焊缝纵向均匀为拉应力分布,焊缝横向均为压应力分布,焊缝热影响区的残余应力分布各异。     

The Bifurcation of the Equatorial Periodic Orbit of the Planar Polynomial Vector Fields

In this paper, we have obtained the necessary and sufficient condition for the set of points at infinity on the plane R ² to be a periodic orbit which is called an equatorial periodic orbit of a planar vector field X(x), and the formulae about the multiplicity of the equatorial periodic orbit of X(x). We have also proved that the main result of [9] is erroneous with regard to the formulae. This work is supported by the NSF of China     

原子力显微镜微探针与光束偏转法在纳米振动检测中的应用

本文探讨了表面弹性波传播的机制,提出了一种利用原子力显微镜微探针与光束偏转法检测纳米振动的新方法,并利用这种方法对表面波质点的纳米振动进行了实时检测.当LiNbO₃晶片被施以13MHz的超高频激振电压时,在原子力显微镜示波器监视端观察到了质点的纳米振动,幅值为6.7nm,频率和驱动电压的频率一致.