Synthesis of Aryl Ethers by Nonactivated Aromatic Nucleophilic Substitution Reactions

The results of a kinetic study of model reactions between substituted phenols and bromobenzene in the presence of potassium carbonate and the copper(I) chloride–8-hydroxyquinoline catalytic complex in N,N-dimethylformamide are presented. The reactions were found to obey a first-order rate law. Both orbital and charge interactions should be taken into account in a consideration of the effect of the structural characteristics of reactants on the rate of reaction. The kinetics of substitution of the phenoxide anion for an aromatically bound halogen atom in activated and nonactivated systems with the formation of practically valuable aryl ethers were comparatively studied. The results presented provide an opportunity to distinguish the common features and regularities of activated and nonactivated aromatic substitution in the test systems.     

A facile entry to l-aryl-4,5-dihydro[1,4]oxazepino-[5,4-a]isoindole-2,7-diones

The titled compounds were prepared by reacting N-(2-bromoethyl)phthalimide with enolates of phenylacetic acid esters. 2,3-Dihydrooxazolo[2,3-a]isoindolones are believed to be intermediates in the process. An X-ray crystallographic analysis was conducted on one of the compounds.     

Asymmetry and magnetism in bis(oximato)-bridged heterobimetallic compounds: a computational approach

A density functional study of exchange coupling was carried out for a series of heterobinuclear oximato-bridged transition metal complexes. Model calculations were used to examine the influence of the electronic configuration of the metal atoms on the coupling constants. This analysis was complemented by a study of the variation of the coupling constant with the most usual structural distortions within this family of compounds. The influence of the nature of the terminal ligands as well as that of the symmetry on the bridge were also investigated.     

Action of nucleophilic agents on the pyrimidine ring

It is shown that 2-alkylpyrimidine methiodides in which the alkyl group is activated by electron-acceptor substituents undergo recyclization to the corresponding 2-methylaminopyridines in an alcohol solution of methylamine. Similar recyclization also takes place without quaternization of the pyrimidine ring when there is a strong electron-acceptor substituent (a nitro group) in the ring.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1400–1405, October, 1978.     

Influence of the structure of the molecules on the capacity for adsorption of 1,3-dienic hydrocarbons on platinum at high positive potentials

Theoretical and Experimental Chemistry -