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101.
M. S. Nikol'skii 《Differential Equations》2003,39(11):1603-1608
102.
I. P. Kuranova K. M. Polyakov E. A. Smirnova W. E. Höhne V. S. Lamzin R. Meijer 《Crystallography Reports》2003,48(6):953-958
Crystals of Saccharomyces cerevisiae inorganic pyrophosphatase suitable for X-ray diffraction study were grown by cocrystallization of the enzyme with cobalt chloride and imidodiphosphate. Saccharomyces cerevisiae is a metal-dependent enzyme which catalyzes hydrolysis of inorganic pyrophosphate to orthophosphate. The three-dimensional structure of this enzyme was solved by the molecular-replacement method and refined at 1.8 Å resolution to an R factor of 19.5%. Cobalt and phosphate ions were revealed in the active centers of both identical subunits (A and B) of the pyrophosphatase molecule. In subunit B, a water molecule was found between two cobalt ions. It is believed that this water molecule acts as an attacking nucleophile in the enzymatic cleavage of the pyrophosphate bond. It was demonstrated that cobalt ions and a phosphate group occupy only part of the potential binding sites (two chemically identical and crystallographically independent subunits have different binding sites). The arrangement of ligands and the structure of the nucleophile-binding site are discussed in relation to the mechanism of action of the enzyme and the nature of the metal activator. 相似文献
103.
Harish C. Bahl Stanley Zionts 《The Journal of the Operational Research Society》1987,38(12):1141-1148
Scheduling the production of several items requires the determination of production quantities in different periods in the presence of resource constraints. Several approximate and heuristic algorithms have been proposed to solve this problem. However, no method for finding an optimal solution has as yet been developed. It is shown that the problem may be solved advantageously using Benders' decomposition. The subproblem in Benders' decomposition is shown to be a transportation problem, and some strategies for solving the master problem are indicated. The paper concludes with a sample problem demonstrating the application of the method. 相似文献
104.
A new grid‐free upwind relaxation scheme for simulating inviscid compressible flows is presented in this paper. The non‐linear conservation equations are converted to linear convection equations with non‐linear source terms by using a relaxation system and its interpretation as a discrete Boltzmann equation. A splitting method is used to separate the convection and relaxation parts. Least squares upwinding is used for discretizing the convection equations, thus developing a grid‐free scheme which can operate on any arbitrary distribution of points. The scheme is grid free in the sense that it works on any arbitrary distribution of points and it does not require any topological information like elements, faces, edges, etc. This method is tested on some standard test cases. To explore the power of the grid‐free scheme, solution‐based adaptation of points is done and the results are presented, which demonstrate the efficiency of the new grid‐free scheme. Copyright © 2005 John Wiley & Sons, Ltd. 相似文献
105.
106.
107.
A. P. S. Selvadurai 《Zeitschrift für Angewandte Mathematik und Physik (ZAMP)》1987,38(5):674-688
The paper examines the problem related to the axisymmetric interaction between an external circular crack and a centrally placed penny-shaped rigid inclusion located in the plane of the crack. The interface between the inclusion and the elastic medium exhibits a Mindlin-type imperfect bi-lateral contact. Analytical results presented in the paper illustrate the manner in which the lateral translational stiffness of the inclusion and the stress intensity factor at the boundary of the external circular crack are influenced by the inclusion/crack radii ratio. 相似文献
108.
S. Gukov 《JETP Letters》1997,65(8):694-700
The manifestly supersymmetric four-dimensional Wess-Zumino model with quenched disorder is considered at the one-loop level.
The infrared fixed points of a beta function form the moduli space ℳ=RP
2, where two types of phases are found: with and without replica symmetry. While the former phase possesses only a trivial
fixed point, this point become unstable in the latter phase, which may be interpreted as a spin glass phase.
Pis’ma Zh. éksp. Teor. Fiz. 65, No. 8, 657–662 (25 April 1997)
Published in English in the original Russian journal. Edited by Steve Torstveit. 相似文献
109.
We show that “top-down” mechanisms of ultrahigh-energy cosmic rays which involve heavy relic particle-like objects predict
a Galactic anisotropy of the highest-energy cosmic rays at the level of minimum ∼ 20%. This anisotropy is large enough to
be either observed or ruled out in the next generation of experiments.
Pis’ma Zh. éksp. Teor. Fiz. 68, No. 2, 99–103 (25 July 1998)
Published in English in the original Russian journal. Edited by Steve Torstveit. 相似文献
110.