Synthesis of 1,5-diazocin-2-ones

Russian Chemical Bulletin - This review is focused on the synthetic approaches to the eight-membered nitrogen heterocycles, 1,5-diazocin-2-ones, exhibiting promising biological activities....     

Stab-Resistant Performance of the Well-Engineered Soft Body Armor Materials Using Shear Thickening Fluid

Stab-resistant body armor can effectively prevent sharp instruments from attacking the protected parts and reduce the threat to human bodies. Shear thickening fluid (STF) is a kind of smart material with variable viscosity and its viscosity can change significantly with external stimuli. The soft and adaptive characteristics of STF provide a new idea for improving the performance of stab-proof materials. In this work, three kinds of soft anti-stabbing materials were designed and prepared with aramid, poly–p–phenylene benzodioxazole (PBO), and carbon fiber fabrics impregnated with STF. Quasi-static puncture tests and dynamic impact tests were conducted to compare the performance of different anti-stabbing structures. The results showed that the peak piercing force of the STF-treated fabrics in the puncture testing was greatly increased than that of neat samples. Against the D2 knife, the maximum impact load of STF/PBO fiber fabric was increased from 55.8 N to 72.9 N, increasing by 30.6%. Against the D3 spike, the maximum impact load of STF/aramid fabric was increased from 128.9 N to 254.7 N, increasing by 197.6%. The mechanical properties of fibers were important factors for the resistance to knives, and the fabric structure was the key point to bear the spike. Optical photographs of fabric fractures and scanning electron microscope analysis indicated that the STF effectively limited the slip of the fiber bundle when the tool penetrated the fabric, which played a positive role in maintaining the tightness and integrity of the fabric structure.     

宽谱调谐二极管激光吸收光谱的数据预处理研究

二极管激光吸收光谱以温度扫描实现快速宽谱调谐,其原始数据不便于传统的处理及运算,适当的预处理是进行后续数据处理的基础。在分析了温度调谐数据特征的基础上,利用Savitzky-Golay滤波器去除了波长序列中温度检测噪声的干扰,选择单调的波长区间对信号幅值进行三次样条插值,以固定的波长点对应采样点,得到一组位置固定的幅值序列用于后期处理。此方法将两列检测数据合并为一列,相同的起始点和固定的波长位置不仅将多周期平均后的信噪比提升为原始数据的6倍,也使多组数据的比较及评价成为可能,一致的波长分辨率保证了线形检测的精确度,减小了吸收峰的频带宽度,有助于后续的处理、运算以及评价。     

Electrophilically Activated Nitroalkanes in Synthesis of 3,4-Dihydroquinozalines

Nitroalkanes activated with polyphosphoric acid serve as efficient electrophiles in reactions with various nucleophilic amines. Strategically placed second functionality allows for the design of annulation reactions enabling preparation of various heterocycles. This strategy was employed to develop an innovative synthetic approach towards 3,4-dihydroquinazolines from readily available 2-(aminomethyl)anilines.     

New measurements of Cabibbo-suppressed decays of mesons with the CLEO-c detector

Using of data collected with the CLEO-c detector, we report on first observations and measurements of Cabibbo-suppressed decays of D mesons in the following six decay modes: pi+ pi- pi0 pi0, pi+ pi+ pi- pi- pi0, pi+ pi0 pi0, pi+ pi+ pi- pi0, eta pi0, and omega pi+ pi-. Improved branching fraction measurements in eight other multipion decay modes are also presented. The measured D --> pi pi rates allow us to extract the ratio of isospin amplitudes A(DeltaI = (3/2) / A(DeltaI = (1/2)) = 0.420 +/- 0.014(stat) +/- 0.016(syst) and the strong phase shift of delta1 = (86.4 +/- 2.8 +/- 3.3) degrees, which is quite large and now more precisely determined.     

Determining the Gibbs energy of ion transfer across water-organic liquid interfaces with three-phase electrodes.

Ions can be transferred between immiscible liquid phases across a common interface, with the help of a three-electrode potentiostat, when one phase is an organic droplet attached to a solid electrode and containing a redox probe. This novel approach has been used in studies to determine the Gibbs energy of anion and cation transfer, ranging from simple inorganic and organic ions to the ionic forms of drugs and small peptides. This method of studying ion transfer has the following advantages: (1) no base electrolytes are necessary in the organic phase; (2) the aqueous phase contains only the salt to be studied; (3) a three-electrode potentiostat is used; (4) organic solvents such as n-octanol and chiral liquids such as D- and L-2-octanol can be used; (5) the range of accessible Gibbs energies of transfer is wider than in the classic 4-electrode experiments; (6) the volume of the organic phase can be very small, for example, 1 microL or less; (7) the experiments can be performed routinely and fast. Herein, the basic 5 principle is outlined, as well as a summary of the results obtained to date, and a discussion on the theoretical treatments concerning the kinetic regime of the three-phase electrodes with immobilized droplets.     

Arytenoid Cartilage Dislocation: A 20-year Experience

SUMMARY: Arytenoid cartilage dislocation is an infrequently diagnosed cause of vocal fold immobility. Seventy-four cases have been reported in the literature to date. Intubation is the most common origin, followed by external laryngeal trauma. Decreased volume and breathiness are the most common presenting symptoms. We report on 63 patients with arytenoid cartilage dislocation treated by the senior author (RTS) since 1983. Significantly more posterior than anterior dislocations were represented. Although reestablishing joint mobility is difficult, endoscopic reduction should be considered to align the heights of the vocal processes. This process may result in significant voice improvement even long after the dislocation. Strobovideolaryngoscopy, laryngeal electromyography, and laryngeal computed tomography (CT) imaging are helpful in the evaluation of patients with vocal fold immobility to help distinguish arytenoid cartilage dislocation from vocal fold paralysis. Familiarity with signs and symptoms of arytenoid cartilage dislocation and current treatment techniques improves the chances for optimal therapeutic results.     

Thermal and base-catalyzed rearrangements of diacyl carbinols

Diacyl carbinols undergo facile thermal and base-catalyzed rearrangements to -ketol esters.     

Panel The integration of voice science, voice pathology, medicine, public speaking, acting, and singing

The integration of voice science, voice pathology, medicine, public speaking, acting, and singing has been central to evolution in all fields. The Voice Foundation Symposia have played a seminal and central role in fostering integration among disciplines. The result has been an improvement in the knowledge and practice in each field. And the future promises to be even more informative and exciting.