High-temperature expansion for nonequilibrium steady states in driven lattice gases

We develop a controlled high-temperature expansion for nonequilibrium steady states of the driven lattice gas, the "Ising model" for nonequilibrium physics. We represent the steady state as P(eta) alpha e(-betaH(eta)-psi(eta)) and evaluate the lowest order contribution to the nonequilibrium effective interaction psi(eta). We see that, in dimensions d > or = 2, all models with nonsingular transition rates yield the same summable psi(eta), suggesting the possibility of describing the state as a Gibbs state similar to equilibrium. The models with the Metropolis rule show exceptional behavior.     

Profiles and Quantization of the Blow Up Mass for Critical Nonlinear Schrödinger Equation

We consider finite time blow up solutions to the critical nonlinear Schrödinger equation For a suitable class of initial data in the energy space H¹, we prove that the solution splits in two parts: the first part corresponds to the singular part and accumulates a quantized amount of L² mass at the blow up point, the second part corresponds to the regular part and has a strong L² limit at blow up time.Part of this work has been supported by grant DMS-0111298.     

On universality of blow-up profile for <Emphasis Type="Italic">L</Emphasis><Superscript>2</Superscript> critical nonlinear Schrödinger equation

We consider finite time blow-up solutions to the critical nonlinear Schrödinger equation iu_t=-u-|u|^4/Nu with initial condition u₀H¹. Existence of such solutions is known, but the complete blow-up dynamic is not understood so far. For a specific set of initial data, finite time blow-up with a universal sharp upper bound on the blow-up rate has been proved in [22], [23].We establish in this paper the existence of a universal blow-up profile which attracts blow-up solutions in the vicinity of blow-up time. Such a property relies on classification results of a new type for solutions to critical NLS. In particular, a new characterization of soliton solutions is given, and a refined study of dispersive effects of (NLS) in L² will remove the possibility of self similar blow-up in energy space H¹.     

Unbounded Entropy in Spacetimes with Positive Cosmological Constant

In theories of gravity with a positive cosmological constant, we consider product solutions with flux, of the form (A)dS _p ×S ^q . Most solutions are shown to be perturbatively unstable, including all uncharged dS _p ×S ^q spacetimes. For dimensions greater than four, the stable class includes universes whose entropy exceeds that of de Sitter space, in violation of the conjectured N-bound. Hence, if quantum gravity theories with finite-dimensional Hilbert space exist, the specification of a positive cosmological constant will not suffice to characterize the class of spacetimes they describe.     

Isolation and characterization of kallosin A,a novel rearranged pseudopterane diterpenoid from the Caribbean sea plume Pseudopterogorgia kallos (Bielschowsky)

The Caribbean alcyonacean Pseudopterogorgia kallos is shown to contain a novel rearranged pseudopterane diterpene, kallosin A (1), possessing several unusual structural features. In addition to having two distinct 2(3H)- and 2(5H)-furanone moieties, kallosin A is based on a new carbon skeleton. The structural assignment of 1 was based mainly on 1D and 2D NMR spectral data and was further supported by accurate mass measurement and single-crystal X-ray diffraction analysis.     

Nonproteolytic cleavage of aspartyl proline bonds in the cellulosomal scaffoldin subunit from Clostridium thermocellum

Previous work from our group [Morag (Morgenstern), E., Bayer, E. A., and Lamed, R. (1991), Appl. Biochem. Biotechnol. 30, 129–136] has demonstrated an anomalous electrophoretic mobility pattern for scaffoldin, the 210-kDa cellulosome-integrating subunit of Clostridium thermocellum. Subsequent evidence [Morag, E., Bayer, E. A., and Lamed, R. (1992), Appl. Biochem. Biotechnol. 33, 205–217] indicated that the effect could be attributed to a nonproteolytic fragmentation of the subunit into a defined series of lowermolecular-weight bands. In the present work, a recombinant segment of the scaffoldin subunit was employed to determine the site(s) of bond breakage. An Asp-Pro sequence within the cohesin domain was identified to be the sensitive peptide bond. This sequence appears quite frequently in the large cellulosomal proteins, and the labile bond may be related to an as yet undescribed physiological role in the hydrolysis of cellulose by cellulosomes.     

A Coding Theory Bound and Zero-Sum Square Matrices

For a code C=C(n,M) the level k code of C, denoted C _k , is the set of all vectors resulting from a linear combination of precisely k distinct codewords of C. We prove that if k is any positive integer divisible by 8, and n=k, M=k2k then there is a codeword in C _k whose weight is either 0 or at most . In particular, if <(4–2)²/48 then there is a codeword in C _k whose weight is n/2–(n). The method used to prove this result enables us to prove the following: Let k be an integer divisible by p, and let f(k,p) denote the minimum integer guaranteeing that in any square matrix over Z _p , of order f(k,p), there is a square submatrix of order k such that the sum of all the elements in each row and column is 0. We prove that lim inf f(k,2)/k<3.836. For general p we obtain, using a different approach, that f(k,p)p( ^{k / ln k )(1+ o} _k ⁽¹⁾⁾.     

Analysis of galectin 1-mediated cell signaling by combined precipitation and electrophoresis techniques

Galectin-1 (GAL1) is a beta-galactoside-binding protein that has been implicated in the regulation of viability of lymphoid cells. However, the signaling pathway governed by the binding of GAL1 to the cell membrane is not understood yet. As a first step toward the elucidation of GAL1-initiated signaling events, electrophoresis techniques such as sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and two-dimensional electrophoresis (2-DE) were used together with precipitation techniques. This allowed us to identify the membrane receptor of GAL1, and to characterize the signal resulting from the binding of GAL1 to this receptor. Our results demonstrate that the tyrosine phosphatase CD45 is the receptor for GAL1, and that the src-type tyrosine kinase Lyn is a target for the effects of GAL1/CD45 interactions in B-cells. Furthermore, these results show the usefulness of combined precipitation and electrophoresis techniques to analyze phosphotyrosine-dependent mechanisms during the study of cell functions.     

On Bianchi permutability of Bäcklund transformations for asymmetric quad-equations

We prove the Bianchi permutability (existence of superposition principle) of Bäcklund transformations for asymmetric quad-equations. Such equations and their Bäcklund transformations form 3D consistent systems of a priori different equations. We perform this proof by using 4D consistent systems of quad-equations, the structural insights through biquadratics patterns and the consideration of super-consistent eight-tuples of quad-equations on decorated cubes.