两种稀土卟啉配合物与大肠杆菌作用的微量热研究

用LKB-2277生物活性检测系统测定了新合成的阳离子型稀土卟啉配合物{[Re(TMP)(H2O)3]Cl, Re=Y、Yb, TMP=5, 10, 15, 20-四(4’-甲氧基苯基)卟啉}在37 ℃时对大肠杆菌作用的产热曲线,根据产热曲线求算了在稀土卟啉配合物作用下,大肠杆菌生长代谢的速率常数k,抑制率I,传代时间tG和半抑制浓度cI,50等热动力学参数.结果表明,稀土卟啉配合物在低浓度下对大肠杆菌有刺激作用,高浓度下为抑制作用,[Yb(TMP)(H2O)3]Cl的半抑制浓度cI,50为143 mg•L-1,其对大肠杆菌的抑制作用优于[Y(TMP)(H2O)3]Cl.     

含硫阴离子表面活性剂的合成及其表面活性

合成了三种分子中分别含有－Ｓ－，－ＳＯ－，－ＳＯ２－基力的羧酸型离子表面活性剂，并研究了它们的表面活性。     

Polymerization‐induced self‐assembly of block copolymer through dispersion RAFT polymerization in ionic liquid

Polymerization‐induced self‐assembly of block copolymer through dispersion RAFT polymerization has been demonstrated to be a valid method to prepare block copolymer nano‐objects. However, volatile solvents are generally involved in this preparation. Herein, the in situ synthesis of block copolymer nano‐objects of poly(ethylene glycol)‐block‐polystyrene (PEG‐b‐PS) in the ionic liquid of 1‐butyl‐3‐methylimidazolium hexafluorophosphate ([BMIN][PF₆]) through the macro‐RAFT agent mediated dispersion polymerization is investigated. It is found that the dispersion RAFT polymerization of styrene in the ionic liquid of [BMIN][PF₆] runs faster than that in the alcoholic solvent, and the dispersion RAFT polymerization in the ionic liquid affords good control over the molecular weight and the molecular weight distribution of the PEG‐b‐PS diblock copolymer. The morphology of the in situ synthesized PEG‐b‐PS diblock copolymer nano‐objects, e.g., nanospheres and vesicles, in the ionic liquid is dependent on the polymerization degree of the solvophobic block and the concentration of the fed monomer, which is somewhat similar to those in alcoholic solvent. It is anticipated that the dispersion RAFT polymerization in ionic liquid broads a new way to prepare block copolymer nano‐objects. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2016 , 54, 1517–1525     

Engineering of chiral nanomaterials for biomimetic catalysis

Chiral nanomaterial-based biomimetic catalysts can trigger a similar biological effect to natural catalysts and exhibit high performance in biological applications. Especially, their active center similarity and substrate selectivity promoted their superior biocatalytic activity. Here, modification of critical elements, such as size, morphology, nanocrystal facets, chiral surface and active sites, for controlling the catalytic efficiency of individual chiral nanoparticles (NPs) and chiral nanoassemblies has been demonstrated, which had a synergistic effect on overcoming the defects of pre-existing nanocatalysts. Noticeably, application of external forces (light or magnetism) has resulted in obvious enhancement in biocatalytic efficiency. Chiral nanomaterials served as preferable biomimetic nanocatalysts due to their special structural configuration and chemical constitution advantages. Furthermore, the current challenges and future research directions of the preparation of high-performance bioinspired chiral nanomaterials for biological applications are discussed.

Chiral nanomaterial-based biomimetic catalysts can trigger a similar biological effect to natural catalysts and exhibit high performance in biological applications.     

Synthesis of phosphorylated calix[4]arene derivatives for the design of solid phases immobilising uranyl cations

With the aim of developing supports for uranyl cations immobilisation, new 1,3-alternate calix[4]arenes bearing both phosphonic acid functions as chelating sites and N-succinimide-4-oxabutyrate as the anchoring arm were synthesised in good yields. The coupling of such calixarenes to a gel was performed and a successful immobilisation of uranyl cations was obtained.