1-杂环芳酰氧基-2,8,9-三氧杂-5-氮杂-1-硅杂三环[3.3.3.0~(1,5)]十一碳烷的研究

本文合成了六个1-杂环芳酰氧基杂氮硅三环和三个1-杂环芳酰氧甲基杂氮硅三环,这些化合物均未见文献报道。通过1~H NMR、IR 和 X 射线衍射的方法,确证上述化台物为五配位结构,分子内的 N→Si 配键强度较大。这是一类低毒或中毒化合物。     

自制离子液体固相微萃取涂层分析人体尿液中的五氯酚

建立了顶空固相微萃取与气相色谱法（HS-SPME-GC）测定人体尿液中五氯酚（PCP）的新方法。 采用溶胶-凝胶法,加入自制的离子液体键合固相微萃取涂层,优化了萃取温度、萃取时间、pH值、离子强度及解吸时间。 结果表明,样品中加入3 g NaCl,溶液的pH值为2,并以一定速度搅拌的条件下,在80 ℃顶空萃取50 min,300 ℃下解吸5 min,方法的检测限为5.0 ng/L,线性范围为0.05～100 μg/L,相对标准偏差(RSD)为5.9%,加标回收率为106.6%。     

Intersection homology theory via rectifiable currents

Here is given a rectifiable currents version of intersection homology theory on stratified subanalytic pseudomanifolds. This new version enables one to study some variational problems on stratified subanalytic pseudomanifolds. We first achieve an isomorphism between this rectifiable currents version and the version using subanalytic chains. Then we define a suitably modified mass on the complex of rectifiable currents to ensure that each sequence of subanalytic chains with bounded modified mass has a convegent subsequence and the limit rectifiable current still satisfies the perversity condition of the approximating chains. The associated mass minimizers turn out to be almost minimal currents and this fact leads to some regularity results.Received: 21 April 2001, Accepted: 15 April 2003, Published online: 1 July 2003     

具有生物活性的有机硅化合物的研究——Ⅶ.1-芳酰氧基-2,8,9-三氧杂-5-氮杂-1-硅杂三环[3.3.3.0~(1,5)]十一碳烷的研究

本文用新的方法合成了九个1-芳酰氧基-2,8,9-三氧杂-5-氮杂-1-硅杂三环[3.3.3.0~(1,5)]十一碳烷(简称1-芳酰氧基杂氮硅三环)。本方法具有产率高,后处理简便等优点。X-射线晶格衍射确定了该类化合物分子内 N→Si 键键长较短,说明配键强度较大。报道该类化合物的 IR,1~H NMR 及 MS,并讨论了质谱断裂机理。     

煤的油团聚的表面热力学理论

本文试图用过程的自由能改变来预言油团聚的热力学稳定性，对具有最低自由能的状态被认为是最稳定状态。本文导出了油团聚过程的自由能，（ｄＦ）Ｔ，ｐ＝４πｒ１＾２γ＾２３「（１－ｃｏｓψ）√２（１－ｃｏｓψ）－ｃｏｓθ（１－ψ－ｎ＾２）。由此可见，自由能的降低是由油滴对煤粒大小的比值，三相接触角和油水之间的表面张力来确定。     

将闭Riemann子流形保角变形成极小子流形

在本文中，通过外围空间的适当保角变形，我们证明了，每个Riemann子流形可以被认作一个极小子流形，我们还研究了这样得到的子流形的稳定性，定理2和3推广了Schoen和S．TYan[2]的结论．     

直角棱镜刚性上盘高效生产技术研究

本文报告直棱镜刚性成组上盘大批量高效生产工艺技术。讨论了棱镜粗磨铣磨成型，精磨磨具的参数选择以及丸片精磨镜盘的面形稳定性分析。给出了聚氨酯平盘抛光工艺参数，报告了这些研究试验结果在生产线上的应用效果。     

分散固相萃取-高效液相色谱-串联质谱法同时测定保健品片剂中5种黄芩素类化合物

基于分散固相萃取-高效液相色谱-串联质谱技术（DSPE-HPLC-MS/MS）,建立了同时测定保健品片剂中野黄芩素、4'-羟基汉黄芩素、去甲汉黄芩素、黄芩素和汉黄芩素的分析方法。以10 mL丙酮提取保健品片剂中的目标成分,75 mg C₁₈吸附剂进行净化。通过优化提取溶剂、吸附剂的种类和用量,达到了提取和净化的目的。结果表明,5种目标物在各自的线性范围内具有良好的线性关系,相关系数（r）均大于0.99,检出限为0.5~40 μg/kg,定量限为2.0~120 μg/kg。使用3种保健品片剂基质进行定量限的1倍、5倍、10倍3个添加水平的加标回收试验,5个目标物的平均回收率为83.1%~106.5%,精密度为0.97%~4.52%。该方法操作简单、灵敏度高、重现性好,适用于保健品片剂中黄芩素类化合物的同时测定。     

双视场准共路多普勒外差干涉仪光学系统设计

针对大气风场矢量的星载探测应用,提出一种双视场准共路多普勒外差干涉仪方案,其采用平面镜视场耦合、K?sters棱镜单光栅干涉仪和一维成像镜的系统结构,可以同时探测两个正交方向不同高度层的视线风速,具有结构紧凑、无运动部件、探测效率高等特点。推导了基于K?sters棱镜的准共路干涉仪非对称量Δd与光栅利特罗角、分光棱镜尺寸等初始光学参数的关系。以基于氧原子红线(O[1D]630 nm)进行星载高层大气风场探测为例,给出了参数优化和系统设计的过程及结果,并对全系统干涉图进行建模仿真。结果表明:双视场准共路多普勒外差干涉仪具有一维空间分辨能力,在不使用视场扫描装置的情况下就可获得两个视场方向不同高度层上的干涉图,借助卫星平台运动可以获得同一目标区域的风场矢量信息。     

High-intensity fluorescence imaging and sensitive electrochemical detection of cancer cells by using an extracellular supramolecular reticular DNA-quantum dot sheath

Acting as a cage-type cellular probe, an extracellular supramolecular reticular DNA-quantum dot (QD) sheath has been developed for high-intensity fluorescence microscopy imaging and the sensitive electrochemical detection of Ramos cells. The extracellular supramolecular reticular DNA-QD sheath is constructed from layer-by-layer self-assembly of DNA-CdTe QD probes and DNA nanowire frameworks functionalized with a Ramos cell-binding aptamer. The DNA-QD sheath forms specifically and quickly on the surface of Ramos cells at physiological temperature, and the assembly of large numbers of DNA-CdTe QD probes on the surface of Ramos cells produces exceedingly high fluorescence intensity. Using the extracellular supramolecular reticular DNA-QD sheath as the cellular probe, Ramos cells can be clearly observed and easily distinguished from a mixture of multiple cancer cells by fluorescence microscopy imaging. Using the new cage-type cellular probe, a sensitive sandwich-type electrochemical strategy has also been developed to achieve accurate quantitative analysis of Ramos cells. Under the optimized conditions, Ramos cells can be detected quantitatively in a range from 10 to 1000 cells with a detection limit of 10 cells. This strategy presents a promising platform for highly sensitive and convenient evaluation of cancer cell levels.