Use of topological indexes for prediction of the activity of 5-lipoxygenase inhibitors in a series of hydroxamates

An effective system for predicting the inhibiting activity with respect to 5-lipoxygenase in a series of hydroxamic acids was developed. The bioactivity is predicted based on three selected topological indexes with one variation of the method of k-nearest neighbors. The system obtained is suitable for selecting the structures of new 5-lipoxygenase inhibitors which can be used as drugs.Translated from Teoreticheskaya i Eksperimental'naya Khimiya, Vol. 29, No. 2, pp. 122–126, March–April, 1993.     

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Enriched Zn $$^{100}$$ MoO $$_4$$ scintillating bolometers to search for $$0\nu 2\beta $$ decay of $$^{100}$$ Mo with the LUMINEU experiment

In the present work, we consider a model with a fermionic field that is non-minimally coupled to gravity in the framework of teleparallel gravity. In order to determine the forms of the coupling and potential function of fermionic field for the considered model, we use the Noether symmetry approach. By applying this approach, for the Friedman–Robertson–Walker metric, we obtain the respective potential and coupling functions as a linear and power-law form of the bilinear \(\Psi \) . Furthermore, we search for the exact cosmological solution of the model. It is shown that the fermionic field plays the role of dark energy.