Interaction between explosive and analyte layers in explosive matrix-assisted plasma desorption mass spectrometry

An HMX/insulin two-layer system was chosen as a model for further investigation of the matrix properties of explosive materials for protein analytes in plasma desorption mass spectrometry. The dependencies of the molecular ion yield and average charge state as a function of the analyte thickness were studied. An increase in the charge state of multiply protonated molecular species was confirmed as the major matrix effect, with the average charge state z at the smallest thickness studied being higher than in matrix-assisted laser desorption/ionization and closer to the value obtained in electrospray ionization under standard acidic conditions. Observed charge state distributions are significantly narrower than the corresponding Poisson distributions, which suggests that the protonation of insulin is limited in plasma desorption by the number of basic sites in the molecule, similar to electrospray ionization. Both the curve displaying total molecular ion yield and the one showing the total charge (proton) yield as a function of the insulin thickness have maxima at a thickness different from an insulin monolayer. These observations diminish the significance of a matrix/analyte interface mechanism for the explosive matrix assistance. Instead, a mechanism related to the chemical energy release during conversion of the explosive after the ion impact is proposed. As additional mechanisms, enhanced protonation of the analyte through collisions with products of the explosive decay is considered, as well as electron scavenging by other products, which leads to a higher survival probability of positively charged protein molecular ions. Copyright 1999 John Wiley & Sons, Ltd.     

Quasi-elastic pn scattering in ^6LiD and ^6LiH targets from 1.1 to 2.4 GeV

A polarized proton beam from SATURNE II, the Saclay polarized targets with Li compounds, and an unpolarized target were used to measure spin-dependent observables for protons scattered on bound nucleons. The beam and target polarizations were oriented vertically. The analyzing power and the depolarization were determined at seven energies between 1.1 and 2.4 GeV. The spin correlation parameter was measured at only 1.1 and 1.6 GeV. Measurements with the target at 1.1 GeV provided data for scattering of polarized protons on neutrons in carbon. The quasi-elastic observables are compared with previous elastic scattering measurements and at 1.1 GeV with predictions of phase shift analyses. Received: 19 April 1999 / Published online: 28 September 1999     

Elastic and quasi-elastic pp scattering in ^6LiH and ^6LiD targets between 1.1 and 2.4 GeV

A polarized proton beam extracted from SATURNE II, the Saclay polarized target with Li compounds, and a target were used to measure elastic and quasi-elastic pp spin-dependent observables in the angular region . The beam and/or target polarizations were oriented vertically. Accurate pp data for the analyzing power , spin-correlation parameter , and the polarization transfer were measured at 1.1 GeV. The observables and were determined at six other energies between 1.6 and 2.4 GeV. At 1.6 GeV, was also obtained. The individual contributions from H, Li, and LiD were deduced. The target provided results on free hydrogen and on protons in carbon. The elastic and quasi-elastic observables are compared with existing data and with phase-shift analysis predictions. Received: 19 April 1999 / Published online: 14 October 1999     

Dynamics of Uric Acid Sorption on Molecularly Imprinted Sorbent

Russian Journal of Applied Chemistry - In order to create an effective sorption method for extracting uric acid from blood plasma, the dynamics of uric acid sorption by a granular molecular...     

Investigation of a fine structure of deuterium thermal desorption spectra from tungsten

The results of deuterium thermal desorption from tungsten after irradiation by 10 keV ions are discussed. A special heating procedure allows features of the fine structure of the thermal-desorption spectra maxima to be revealed.     

The "hockey sticks" effect revisited: the conformational and electronic properties of 3,7-dithia-1,5-diazabicyclo[3.3.1]nonane from the QTAIM perspective

The conformational effects in bicyclo[3.3.1]nonanes, while thoroughly studied, have not yet received the full theoretical explanation. R. F. W. Bader's quantum theory of atoms in molecules presents unique opportunities for studying the stereoelectronic interactions (SEI) and weak intramolecular bonding leading to these effects. Here, we report the study of 3,7-dithia-1,5-diazabicyclo[3.3.1]nonane by means of the topological analysis of the calculated (MP2(full)/6-311++G**) and experimental (X-ray derived) charge density to reveal the origins of the so-called "hockey sticks" effect observed in similar compounds. A new explanation of the relative stability of bicyclo[3.3.1]nonane conformers based on the analysis of the QTAIM atomic energies is given. The H···H and S···S interactions in bicyclo[3.3.1]nonane and its dithia derivatives are shown to be significant factors contributing to the differences in the relative stability of the conformers.     

Optical and Magneto-Optical Properties of Multilayer Nanosized [Co/TiO2]n Films

Physics of the Solid State - Abstract—The optical and magneto-optical properties of the metal–dielectric multilayer [Co/TiO2]n structures with 2–4-nm-thick layers prepared on a...     

Nonclassical nucleation kinetics in the crystallization of a supercooled melt

A molecular dynamics simulation of homogenous nucleation of a crystal in supercooled aluminum melt is performed. Nucleation rates at a temperature of 900 K in the range of pressures from 12 to 15 GPa are calculated. Analysis of the mean first-passage times of crystalline cluster sizes is performed. A stepwise dependence of the mean first-passage time on crystal nucleus size is observed, in contrast to the sigmoidal dependence that follows from classical nucleation theory. Based on the data from atomistic simulations, it is established that the form of the free energy barrier during nucleation differs significantly from the one assumed in classical nucleation theory for a spherically symmetric nucleus. It is supposed that the observed differences are apparently due to the complex structure of the crystalline nucleus.     

Optical harmonic generation in magnetic garnet epitaxial films near the fundamental absorption edge

Spectra of the second and third optical harmonics generated in epitaxial films of magnetic garnets were studied in the ranges 1.7–3.2 and 2.4–4.2 eV, respectively. A large magnetic contrast was revealed in second-optical-harmonic spectra, which reaches 100% at certain photon energies. By contrast, the symmetry-allowed magnetic contribution to spectra of the third optical harmonic was not found. While linear absorption in ferrite-garnet films grows by two orders of magnitude above the fundamental absorption edge at ～3.2 eV, the intensity of nonlinear spectra did not reveal any noticeable increase over this spectral range.     

Spontaneous Magnetodielectric Effect and Its Coupling to the Lattice Dynamics in Fluoroperovskites

Journal of Experimental and Theoretical Physics - Experimental results on temperature dependences of the low-frequency dielectric permittivity of the group of magnetic fluoroperovskites with...