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21.
Mark A. Pinsky 《Proceedings of the American Mathematical Society》2004,132(6):1729-1737
We state and prove sufficient conditions for the absolute integrability of the inverse of the continuum wavelet kernel.
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Despite the burgeoning interest in the various biological functions and consequent therapeutic potential of the vast number of oligosaccharides found in nature on glycoproteins and cell surfaces, the development of combinatorial carbohydrate chemistry has not progressed as rapidly as expected. The reason for this imbalance is rooted in the difficulty of oligosaccharide assembly and analysis that renders synthesis a rather cumbersome endeavor. Parallel approaches that generate series of analogous compounds rather than real libraries have therefore typically been used. Since generally low affinity is obtained for interactions between carbohydrate receptors and modified oligosaccharides designed as mimetics of natural carbohydrate ligands, glycopeptides have been explored as alternative mimics. Glycopeptides have been proven in many cases to be superior ligands with higher affinity for a receptor than the natural carbohydrate ligand. High-affinity glycopeptide ligands have been found for several types of receptors including the E-, P-, and L-selectins, toxins, glycohydrolases, bacterial adhesins, and the mannose-6-phosphate receptor. Furthermore, the assembly of glycopeptides is considerably more facile than that of oligosaccharides and the process can be adapted to combinatorial synthesis with either glycosylated amino acid building blocks or by direct glycosylation of peptide templates. The application of the split and combine approach using ladder synthesis has allowed the generation of very large numbers of compounds which could be analyzed and screened for binding of receptors on solid phase. This powerful technique can be used generally for the identification and analysis of the complex interaction between the carbohydrates and their receptors. 相似文献
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Volume of a small Extrinsic Ball in a Submanifold 总被引:1,自引:0,他引:1
For a submanifold Mp R, we determine a two-term asymptoticformula for vol (Mp B(x)) for x Mp as 0. The second termis a quadratic curvature invariant of the second fundamentalform of the imbedding. Imbedded spheres are characterized amongcompact hypersurfaces by this term. 相似文献
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Ross G. Pinsky 《Random Structures and Algorithms》2015,46(2):362-390
Consider a permutation σ ∈ Sn as a deck of cards numbered from 1 to n and laid out in a row, where σj denotes the number of the card that is in the j‐th position from the left. We study some probabilistic and combinatorial aspects of the shuffle on Sn defined by removing and then randomly reinserting each of the n cards once, with the removal and reinsertion being performed according to the original left to right order of the cards. The novelty here in this nonstandard shuffle is that every card is removed and reinserted exactly once. The bias that remains turns out to be quite strong and possesses some surprising features. © 2013 Wiley Periodicals, Inc. Random Struct. Alg., 46, 362–390, 2015 相似文献
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Ross G. Pinsky 《Proceedings of the American Mathematical Society》1999,127(11):3319-3327
We consider the inhomogeneous equation
where , and , and give criteria on , and which determine whether for all and all the solution blows up in finite time or whether for and sufficiently small, the solution exists for all time.
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The spectral gaps and thus the exponential rates of convergenceto equilibrium are compared for ergodic one-dimensional diffusionson an interval. One of the results may be thought of as thediffusion analogue of a recent result for the spectral gap ofone-dimensional Schrödinger operators. The similaritiesand differences between spectral gap results for diffusionsand for Schrödinger operators are also discussed. 相似文献
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The effect of instanton-anti-instanton interactions on current correlation functions in massless QCD
William F. Palmer Stephen S. Pinsky 《Zeitschrift fur Physik C Particles and Fields》1980,3(3):209-222
The leading order effects, away from the Dilute Gas Approximation, of instanton-antiinstanton interactions are studied in massless QCD. Propagation and current correlation functions are computed in the interacting dilute gas. While no mass is generated, power law corrections are achieved for the correlation function entering intoe + e ? annihilation. 相似文献