Determination of serotonin in plasma by liquid chromatography with electrochemical detection

The four major hydroperoxides derived from autoxidation or lipoxygenase action on linoleic acid or on methyl linoleate and their corresponding alcohol derivatives are resolved by high-performance liquid chromatography on Zorbax SIL 3 micron particulate columns irrigated with hexane-diethyl ether-acetic acid mixtures. The four major linoleic acid hydroperoxides are interconverted at different rates in benzene or carbon tetrachloride solutions but are stable to storage under nitrogen at -70 degrees C for several months.     

Local existence of solutions of impedance initial-boundary value problem for non-linear Maxwell equations

Local existence of solutions of a mixed problem for non-linear Maxwell equations is proved. The solution is so regular that its third derivatives are from L₂. However, the considered problem is characteristic we were able to obtain necessary estimate because compatibility conditions were used.     

Randwertaufgaben in der verallgemeinerten Potentialtheorie

The Neumann and Dirichlet boundary value problem of generalized potential theory is considered. Based on a compact imbedding result, existence and uniqueness theorems are obtained for Riemannian manifolds with compact boundary (‘interior and exterior domains’).     

Stability of ferrous oxide in molten liCl+KCl eutectic at 470°C

Studies of reactions between oxide and Fe²⁺ ions in molten LiCl+KCl eutectic have shown that ferrous oxide is stabilizedin the form of a solid solution FeOLiFeO₂. Potentiometric titrations with an yttria-stabilized zirconia electrode(indicator of pO^2?) and an iron electrode have first given for y, corresponding to the solid solution composition Fe_1-yLi_yO, a value between 0 and 0.1, and secondly shown the formation of non-stoichiometric ferrous oxide. We have alsosuggested a mechanism for the formation of the solid solution Fe_1-yLi_yO.     

A theoretical investigation of gadolinium (III) solvation in molten salts

The solvation of lanthanides [here Gd(III)] in molten LiCl and KCl has been studied using a classical solvation approach, based on clusters of increasing size. In particular, density-functional calculations have been carried out on charged and neutral clusters, containing up to 35 chlorine halide molecules. A number of properties have been then evaluated and analyzed, including structural, vibrational, and thermochemical data. Special attention has also been devoted to the analysis of the local structure of the solvent surrounding the Gd3+ cation, a problem deeply investigated by experimentalists. Our results show that the charged clusters are not suitable to model the first solvation shell in such species, since their structures are strongly affected by the large electrostatic contribution. In contrast, more reliable simulations are obtained using the neutral clusters. In the latter, the coordination of Gd(III) in molten salts is computed to be 8 or 6, according to the salt LiCl or KCl. Furthermore, a good agreement is found with the experimental structural data and Raman spectra. Finally, preliminary results of potential interest for the estimation of solvation thermodynamics, a key parameter for exploiting molten salt chemistry, are reported for neutral clusters.     

Highly substituted pyrrolidinones and pyridones by 4-CR/2-CR sequence

[reaction: see text] By combining a Ugi four-component reaction of isocyanides, phosphonoacetic acids, primary amines, and glyoxals or alternatively 3-keto aldehydes with a subsequent Wittig ring-closing reaction (using the Horner/Wadsworth/Emmons variant (HWE)), highly substituted 5-oxo-2,5-dihydro-1H-pyrrole-2-carboxylic acid amides and 6-oxo-1,2,3,6-tetrahydro-pyridine-2-carboxylic acid amides can be assembled, respectively. The corresponding tandem of a Passerini reaction on 3-keto aldehydes and subsequent Wittig ring closure does not afford the expected six-membered 6-oxo-3,6-dihydro-2H-pyran-2-carboxylic acid amides but instead leads to the formation of 4-oxo-pent-2-enoic acid amides via an elimination route.     

Conformational and thermodynamic studies of alkaline subhalides M2X (M = Li, Na, K, Rb; X = F, Cl, Br, I)

Alkaline subhalides M₂X (M = Li, Na, K, Rb; X = F, Cl, Br, I) were investigated using DMol software combined with thermostatistical techniques to obtain thermodynamic data for studying the stability of these subhalides. Validation of these results was checked by establishing a link with the experimental MX-M phase diagrams by a simple empirical relation.