Thermal Decomposition of 3'-Azidothymidine

The kinetics of thermal decomposition of 3'-azidothymidine (AZT) in melt at 140-201°C were studied by the thermogravimetric and manometric methods. The process follows the first-order kinetics and is decribed by the Arrhenius equation: k = 1014.7±0.5 exp[-(38100±900)/RT] (1/s). The kinetic and activation parameters are typical of thermal decomposition of aliphatic azides; they suggest that decomposition of the azido group is the rate-determining stage. The formation of nitrogen (1 mol per mole of AZT), furan, methyl alcohol, water, and carbon dioxide was confirmed by mass spectrometry. Thymine was found to be one of the condensed products of thermal decomposition of 3'-azidothymidine.     

Formation of substituted 1,2,4-triazoles and 3h- 1,3,4-benzotriazepines from 5-aryltetrazoles and N-arylbenzimidoyl chlorides (review)

The review discusses the results obtained in the synthesis of substituted 1,2,4-triazoles and 3H-1,3,4-benzotriazepines from 5-aryltetrazoles and N-arylbenzimidoyl chlorides. The farther possibilities of obtaining 3H-1,3,4-benzotriazepines, the mechanism of their formation, and the physical and chemical properties have been assessed.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 907–912, July, 1993.     

Extremal Problems for Operators in Banach Spaces Arising in the Study of Linear Operator Pencils, II

This paper is devoted to the study of operators satisfying the condition

Tetrazolium salts (review)

A summary is given for the methods of preparing tetrazolium salts, the physicochemical properties of these compounds, and their application in research and industry.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1587–1599, December, 1990.