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101.
Most materials exhibit a change in stress-strain relationship when subjected to fatigue stresses. In this work, the effect of this change on the stress distribution across the throat of notched-plate specimens of mild steel is examined. Using a set of strain gages, the strain distribution across the specimens was determined under dynamic conditions for various numbers of cycles. Tests of unnotched specimens were used to obtain the cyclic stress-strain properties for corresponding numbers of cycles, and from these data the stress distribution in the notched specimens was determined. Tests in which the strain amplitude at the notch root was held constant revealed a decreasing maximum stress with fatigue cycles. In another series of tests, in which the load amplitude was constant, the maximum stress amplitude was observed to decrease with number of fatigue cycles, despite an increasing strain amplitude. In both types of tests, the stress-concentration factor was observed to decrease with increasing number of fatigue cycles.  相似文献   
102.
Procedures for the synthesis of thirty-six 5-methyl-3-(substituted)-[1,2,4]triazines have been described. These compounds were evaluated for antagonism at metabotropic glutamate receptor subtype 5 (mGluR5). Two compounds, 5b and 3c, were determined to be low micromolar inhibitors of mGluR5.  相似文献   
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The third industrial fluid properties simulation challenge was held from March to September 2006. As in the previous two events contestants were challenged to predict specific, industrially relevant, properties of fluid systems. Their efforts were judged based on the agreement of the predicted values with previously unpublished experimental data (provided by researchers at ExxonMobil and DuPont). The focus of this contest was on the transferability of modeling methods—the ability to predict properties for materials that are chemically different, or at different state points, to those used in model parameterization and validation. Nine groups attempted to compute bubble point pressures for mixtures of 1,1,1,2,3,3,3-heptafluoropropane (HFC-227ea) and ethanol at 343 K, given data for mixtures at 283 K, and given the pure component vapor pressures. They used a range of different techniques including statistical mechanical and molecular simulations-based approaches. Four of the groups were recognized for providing predictions that were significantly more accurate than would be obtained by extrapolation using the NRTL model (the standard engineering approach). Three groups undertook the more challenging “molecular transferability” problem, attempting to predict shear viscosities at two different state points for a range of diols and triols for which little experimental data was available.  相似文献   
105.
A major limitation in the use of goal programming has been the lack of an efficient algorithm for model solution. Schniederjans and Kwak recently published a proposal for more efficient solution of goal programming models utilizing dual simplex procedures. A goal programming algorithm based upon that method has been coded, as well as a revised, simplex-based algorithm. These algorithms are compared in terms of accuracy and time requirements with algorithms previously presented by Lee and by Arthur and Ravindran. Solution times for a series of 12 goal programming models are presented. The dual simplex method appears to have superior computational times for models with a large proportion of positive deviational variables in the solution. The revised simplex algorithm appears more consistent in time and accuracy for general goal programming models.  相似文献   
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If g1, g2, …, g2n?1 is a sequence of 2n ? 1 elements in an Abelian group G of order n, it is known that there are n distinct indices i1, i2, …, in such that 0 = gi1 + gi2 + ? + gin. In this paper a suitably general condition on the sequence is given which insures that every element g in G has a representation g = gi1 + gi2 + ? + gin as the sum of n terms of the sequence.  相似文献   
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The time-dependent turbulent Navier–Stokes equations are solved numerically by a finite element method with an algebraic eddy viscosity model (Baldwin–Lomax formulation) for oscillating turbulent channel flows. The method of averaging is used to analyse the resulting periodic motion of the fluid. Numerical results are obtained for various Strouhal numbers and relative amplitudes. A comparison is made between the numerical and published experimental results. It appears that for low relative amplitudes in a certain range of frequencies the agreement is satisfactory.  相似文献   
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