全文获取类型
收费全文 | 1546篇 |
免费 | 30篇 |
国内免费 | 4篇 |
专业分类
化学 | 1115篇 |
晶体学 | 16篇 |
力学 | 22篇 |
数学 | 104篇 |
物理学 | 323篇 |
出版年
2021年 | 7篇 |
2020年 | 12篇 |
2019年 | 20篇 |
2018年 | 18篇 |
2017年 | 14篇 |
2016年 | 21篇 |
2015年 | 13篇 |
2014年 | 33篇 |
2013年 | 66篇 |
2012年 | 47篇 |
2011年 | 64篇 |
2010年 | 34篇 |
2009年 | 45篇 |
2008年 | 98篇 |
2007年 | 70篇 |
2006年 | 76篇 |
2005年 | 83篇 |
2004年 | 89篇 |
2003年 | 66篇 |
2002年 | 67篇 |
2001年 | 33篇 |
2000年 | 57篇 |
1999年 | 28篇 |
1998年 | 22篇 |
1997年 | 22篇 |
1996年 | 20篇 |
1995年 | 15篇 |
1994年 | 24篇 |
1993年 | 10篇 |
1992年 | 23篇 |
1991年 | 16篇 |
1990年 | 15篇 |
1989年 | 9篇 |
1987年 | 11篇 |
1986年 | 15篇 |
1985年 | 22篇 |
1984年 | 41篇 |
1983年 | 15篇 |
1982年 | 24篇 |
1981年 | 29篇 |
1980年 | 25篇 |
1979年 | 29篇 |
1978年 | 17篇 |
1977年 | 20篇 |
1976年 | 18篇 |
1975年 | 13篇 |
1974年 | 9篇 |
1973年 | 7篇 |
1972年 | 7篇 |
1968年 | 6篇 |
排序方式: 共有1580条查询结果,搜索用时 15 毫秒
131.
Supramolecular Polyelectrolyte Complexes of Bone Morphogenetic Protein‐2 with Sulfonated Polyrotaxanes to Induce Enhanced Osteogenic Differentiation 下载免费PDF全文
132.
133.
The carbazoles 1 and dibenzofurans 2 having naphthalimide unit were synthesized by the cross coupling reaction of 4-bromonaphthalimide 3 with aniline and phenol derivatives followed by the intramolecular cyclization, respectively. The chromophores 1c and 2c substituted methoxy group exhibited the strong fluorescence solvatochromism. 相似文献
134.
A novel amphiphilic Tb(3+) complex (TbL(+)) having anionic bis(pyridine) arms and a hydrophobic alkyl chain is developed. It spontaneously self-assembles in water and gives stable vesicles that show sensitized luminescence of Tb(3+) ions at neutral pH. This TbL(+) complex is designed to show coordinative unsaturation, i.e., water molecules occupy some of the first coordination spheres and are replaceable upon binding of phosphate ions. These features render TbL(+) self-assembling receptor molecules which show increase in the luminescence intensity upon binding of nucleotides. Upon addition of adenosine triphosphate (ATP), significant amplification of luminescent intensity was observed. On the other hand, ADP showed moderately increased luminescence and almost no enhancement was observed for AMP. Very interestingly, the increase in luminescence intensity observed for ATP and ADP showed sigmoidal dependence on the concentration of added nucleotides. It indicates positive cooperative binding of these nucleotides to TbL(+) complexes preorganized on the vesicle surface. Self-assembly of amphiphilic Tb(3+) receptor complexes provides nanointerfaces which selectively convert and amplify molecular information of high energy phosphates linked by phosphoanhydride bonds into luminescence intensity changes. 相似文献
135.
1,2,3-Benzotriazin-4(3H)-ones and 1,2,3,4-benzothiatriazine 1,1(2H)-dioxide reacted with isocyanides in the presence of a palladium catalyst to give 3-(imino)isoindolin-1-ones and 3-(imino)thiaisoindoline 1,1-dioxides, respectively, in high yield. An intermediate azapalladacycle was generated through denitrogenation of the triazine moiety, and an isocyanide was incorporated therein. 相似文献
136.
We study the survival probability and the growth rate for branching random walks in random environment (BRWRE). The particles
perform simple symmetric random walks on the d-dimensional integer lattice, while at each time unit, they split into independent copies according to time–space i.i.d. offspring
distributions. The BRWRE is naturally associated with the directed polymers in random environment (DPRE), for which the quantity
called the free energy is well studied. We discuss the survival probability (both global and local) for BRWRE and give a criterion
for its positivity in terms of the free energy of the associated DPRE. We also show that the global growth rate for the number
of particles in BRWRE is given by the free energy of the associated DPRE, though the local growth rate is given by the directional
free energy. 相似文献
137.
Ono Y Minami A Noike M Higuchi Y Toyomasu T Sassa T Kato N Dairi T 《Journal of the American Chemical Society》2011,133(8):2548-2555
Fusicoccin A and cotylenin A are structurally related diterpene glucosides and show a phytohormone-like activity. However, only cotylenin A induces the differentiation of human myeloid leukemia cells. Since the cotylenin A producer lost its ability to proliferate during preservation, a study on the relationship between structure and activity was carried out and a modified fusicoccin A with hydroxyl group at the 3-position showed a similar biological activity with that of cotylenin A. We then searched for an enzyme source that catalyzes the introduction of a hydroxyl group into the 3-position and found that brassicicene C, which is structurally related to fusicoccin A with hydroxyl group at the 3-position, was produced by Alternaria brassicicola ATCC96836. We recently cloned a brassicicene C biosynthetic gene cluster including the genes encoding fusicocca-2,10(14)-diene synthase and two cytochrome P450s, which were responsible for the formation of fusicocca-2,10(14)-diene-8β,16-diol. In this study, we report that a α-ketoglutarate dependent dioxygenase, the gene coding for which was located in the cluster, catalyzed a hydroxylation at the 3-position of fusicocca-2,10(14)-diene-8β,16-diol. On the other hand, a α-ketoglutarate-dependent dioxygenase, which had been identified in a fusicoccin A biosynthetic gene cluster, catalyzed the 16-oxidation of fusicocca-2,10(14)-diene-8β,16-diol to yield an aldehyde (8β-hydroxyfusicocca-1,10(14)-dien-16-al), although both dioxygenases had 51% amino acid sequence identity. These findings suggested that the dioxygenases played critical roles for the formation of the fusicoccin A-type and cotylenin A-/brassicicene C-type aglycons. Moreover, we showed that short-chain dehydrogenase/reductase located in the fusicoccin A biosynthetic gene cluster catalyzed the reduction of the aldehyde to yield fusicocca-1,10(14)-diene-8β,16-diol. 相似文献
138.
Naren G Nishida I Shimada Y Tsuji Y Bai S Okaue Y Yokoyama T 《Journal of colloid and interface science》2011,353(1):331-334
This study elucidates the effect of zinc (Zn), which is an anticorrosive water additive, on the formation of silica scales from cooling water. In these experiments, the silica scales were analyzed by EPMA, and the results indicate that Zn is sorbed into the silica scales during formation. Measurements of the solubility of Zn(OH)(2) at various concentrations of silicic acid demonstrate that Zn is present as a silicato complex of Zn (SCZ) in cooling water. From adsorption experiments of the SCZ on silica and alumina, which are major components of the silica scales, it can be concluded that the SCZ accelerates the formation of silica scales from cooling water. 相似文献
139.
Eiichi Masumoto Hiroshi Maruoka Fumi Okabe Sho Nishida Yuki Yoshimura Toshihiro Fujioka Kenji Yamagata 《Journal of heterocyclic chemistry》2011,48(1):96-104
Dihydropyridazinones 4a , 4b , N‐substituted dihydropyrazoles 5b , 5c , 5d , and O‐substituted pyrazoles 6a , 6b , 6c , 6d have been synthesized starting from spirocyclopropanepyrazole derivative 2 . Treatment of 2 with α‐chloro esters, e.g., methyl chloroacetate, ethyl chloroacetate, isopropyl chloroacetate, and tert‐butyl chloroacetate, in potassium carbonate/sodium iodide system caused ring opening and subsequent C‐ or N‐attack nucleophilic substitution to give the corresponding dihydropyridazinones 4a , 4b and N‐substituted dihydropyrazoles 5b , 5c , 5d . On the other hand, in the absence of sodium iodide, O‐substituted pyrazoles 6a , 6b , 6c , 6d were obtained from 2 via an O‐attack nucleophilic substitution. J. Heterocyclic Chem., 2011. 相似文献
140.
Noriaki Nishiguchi Takafumi Kinuta Yoko Nakano Dr. Takunori Harada Dr. Nobuo Tajima Tomohiro Sato Prof. Dr. Michiya Fujiki Prof. Dr. Reiko Kuroda Prof. Dr. Yoshio Matsubara Dr. Yoshitane Imai 《化学:亚洲杂志》2011,6(4):1092-1098
The solid‐state chiral optical properties of a 4‐(2‐arylethynyl)‐benzoic acid/amine supramolecular organic fluorophore can be controlled by changing the arylethynyl group of the achiral 4‐(2‐arylethynyl)‐benzoic acid component molecule rather than the chirality of the amine component molecule. 相似文献