解弹性波动力学问题的部分分离变量-有限差分方法

本文提出一种适用于层状介质、埋藏点源模型的,求解弹性波传播动力学问題的部分分离变量-有限差分方法。它具有计算频域宽、精度高、稳定性好的特点。为了检验本方法的功能,我们给出了一个多层介质模型的数值计算结果。     

光纤导波偏振态实时测量装置

本文详细介绍了多通道光纤导波偏振态实时测量装置的设计和结构，对几种偏振光进行了测试，用Ｐｏｉｎｃａｒｅ球表示法和椭圆表示法在计算机上实时显示其偏振态，已具备初步的应用价值。     

离轴椭圆矢量光场传输中的光斑演变

对离轴椭圆矢量光场的传输特性进行了研究. 推导出离轴椭圆矢量光场在自由空间传输电场和光强的解析表达式. 数值分析结果表明, 离轴高阶圆柱矢量光场具有非对称的光强分布, 传输后的光强分布由传输距离、错位位移、椭圆率决定. 在传输过程中除了光斑会展宽外, 光场中的暗斑会逐渐消失, 最终趋于一种稳态光强分布; 相对于初入射平面的椭圆光斑, 稳态椭圆光斑长短轴互换了. 研究结果有助于深入理解离轴情况下椭圆矢量光场的动态传输特性, 同时可以指导实际椭圆矢量光场的校准.     

等离子体气动激励机理数值研究

基于介质阻挡与准直流电弧放电的物理过程, 分析了它们的气动激励机理, 建立了各自的气动激励模型, 并分别研究了它们对低速和超声速流动的激励效果. 结果显示: 介质挡板放电等离子体气动激励机理是改变了连续流体中的三种力, 即由牛顿内摩擦引起的剪切应力、由电动力学引起的体积力及由压力突变引起的冲击力, 其中基于电动力学的体积力效应占主导地位; 临近空间环境中体积力的作用效果更强, 诱导速度更大; 超声速来流下准直流电弧放电气动激励机理主要是等离子体的热阻塞效应, 本文所建立的爆炸丝传热模型可以用于仿真其控制激波的过程; 热电弧对于超声速来流而言就像一个具有一定斜坡角度的虚拟突起, 可用于高超声速飞行器前体激波的控制.     

Kinetic assay of antitrypsin in human serum by a surface acoustic wave (SAW)-impedance sensor

Antitrypsin in human serum was determined by using both the SAW-impedance sensor system and spectrophotometry, indicating that the mean value for women was significantly higher than the mean value for men; the value for acute pancreasis patients is about 2-folds of the normal values, and there is no significant difference between the acute pancreasis patients and the pancreatic cancer patients.     

萘相吸光光度法研究

本文以萘作为固体萃取剂，以镍－丁二酮肟显色体系为例进行实验，探索出一种新的固相吸光光度法－萘相吸光光度法。镍在０－１００μｇ／５０ｍＬ范围内符合比耳定律，方法应用于水样中痕量镍的分析，结果良好。此种新的分析方法分离富集和显色测定两步相结合。灵敏度高，选择性好，快速简便，是一种很有发展前途的痕量元素分析方法。     

Drug discovery based on the structure of FKBP12: Design,synthesis and evaluation of <Emphasis Type="Italic">L</Emphasis>-1,4-thiazane-3-carboxylic acid derivatives as neuroimmunophilin ligands

By choosing neuroimmunophilin FKBP12 as a therapeutical target, we have attempted to discover a new structural drug for treating neurodegenerative disease. This drug should possess neurotrophic activity and not affect the immune system. Based on the crystal structure of FKBP12, FK506 and Calcineurin complex, a series of small organic molecules were designed. These molecules were to have the ability of binding to FKBP12 in a virtual screening. By using a solution parallel synthetic method, these compounds were synthesized. The neuroprotective and neuroregenerative activities of these compounds were evaluated by binding assays, PC12 cells survival and neurite outgrowth model, chick dorsal root ganglion cultures (DRG) and 6-OHDA lesioned mice sympathetic nerve endings model. The evaluation results of these compounds showed that compound N308 has great promise as a candidate for a neuroprotective and neuroregenerative agent. Supported by the National Basic Research Program of China (Grant No. G1998051107) and Hi-tech Research and Development Program of China (Grant No. 2002AA233051)     

Titrations with piezoelectric monitoring : Part 2. Compleximetric titrations and precipitation titrations

A piezoelectric detector is used to monitor titration reactions involving complex formation or precipitation. Analytes at concentrations down to 10^?4 mol 1^?1 can be determined. The frequency shift in the compleximetric titrations is affected by the composition of the solution, the buffer and competing ligands present in the solution. Factors influencing the frequency shift in the precipitation titration are also investigated.