脯氨酸催化的不对称Aldol反应的研究进展

不对称合成是手性药物制备的核心环节,A ldol反应是重要的形成C—C键的反应之一,在全合成中有广泛应用.脯氨酸的两个异构体均价廉易得,作为一个非金属不对称催化试剂,它催化的不对称A ldol反应立体选择性高,有很好的应用前景.本文就近二十年来脯氨酸催化A ldol反应的机理,溶剂效应,最新进展三方面进行了介绍.     

第2届天然和合成大分子的分离和鉴定国际会议(Ⅰ)

本届大会的简称为SCM-2,即为分离（separation）,鉴定（Characterization）和大分子（Macromolecules）i字字头的缩。丐,由比利时Ordibo组织主办,于2005年2月2只至4日在荷兰Amsterdam市的Mirandapavilijon举行。     

柱状装药预制破片缩比战斗部爆炸冲击波和破片的作用时序

针对柱状装药的周向预制破片战斗部,结合无量纲分析方法和爆炸驱动理论,确定了影响破片和冲击波相遇位置的关键参数,给出了由缩比战斗部推广预测原型战斗部爆炸产生的破片冲击波作用时序的方法。采用ANSYS/LS-DYNA有限元软件进行数值模拟,对比验证了理论分析和数值试验结果,分析了战斗部缩比比例对冲击波和破片作用时序的影响。结果表明:缩比模型与原型战斗部爆炸产生的破片和冲击波的相遇位置之比和相遇时间之比主要取决于两模型的质量比,在不考虑破片速度衰减时,两模型中载荷相遇位置之比和相遇时间之比等于其质量比的0.33次方。受破片速度衰减影响,该方法仅适用于质量缩比不小于0.2的模型。     

SU-8光栅结构中的液晶激光特性

设计制作了SU-8光栅结构的染料掺杂手性向列相液晶激光器件,在器件正面和侧面均实现了随机激光辐射。将激光染料PM597、手性剂S-811、向列性液晶TEB30A按一定比例均匀混合,注入反平行摩擦处理的液晶盒中,器件的下基板通过光掩模法刻蚀出周期为15μm的光栅。利用532 nm的Nd∶YAG固体脉冲激光器作为泵浦源,器件的侧面既在580~590 nm范围内出现了多个离散分立的随机激光辐射峰,FWHM约0.19 nm,又在579~585 nm范围内出现独立的两个激光辐射峰,FWHM约0.19 nm;在器件正面获得了584~590 nm范围的随机激光辐射谱,FWHM约0.17 nm。加热器件至61℃,液晶相变为各向同性态,器件侧面仍出现了波长约590.60 nm、FWHM约0.24 nm的激光辐射峰。分析得出,液晶盒中引入SU-8光栅结构后,光子同时在液晶分子间多重散射和SU-8光栅中布拉格反射获得反馈放大,两种机制相辅相成。器件侧面出现的独立激光辐射峰主要由SU-8光栅布拉格反射提供反馈放大形成,而器件侧面和正面的随机激光辐射峰主要由液晶分子间多重散射提供反馈放大形成。     

Adaptive neural network consensus tracking control for uncertain multi-agent systems with predefined accuracy

Nonlinear Dynamics - This paper proposes the consensus tracking control problem for a class of uncertain nonlinear multi-agent systems. By using a group of nonnegative functions, an adaptive neural...     

VisAct: a visualization design system based on semantic actions

Current visualization design toolkits help users to explore data and create visualizations. However, most of these systems do not record the executed actions during the visualization construction process with semantic context. In this paper, we present VisAct, a visualization design system based on semantic actions, that helps average users to construct visualizations step by step. Our system contributes a set of action-based visualization components and a high-level grammar for semantic actions. VisAct also guides the visualization construction process and provides an action tracker for history management and data collection. We demonstrate the usability of VisAct by visualizations and a plugin application. Finally, we conduct a user study to evaluate the efficiency and effectiveness of our system.     

The Applications of Order Reduction Methods in Nonlinear Dynamic Systems

Two different order reduction methods of the deterministic and stochastic systems are discussed in this paper. First, the transient proper orthogonal decomposition (T-POD) method is introduced based on the high-dimensional nonlinear dynamic system. The optimal order reduction conditions of the T-POD method are provided by analyzing the rotor-bearing system with pedestal looseness fault at both ends. The efficiency of the T-POD method is verified via comparing with the results of the original system. Second, the polynomial dimensional decomposition (PDD) method is applied to the 2 DOFs spring system considering the uncertain stiffness to study the amplitude-frequency response. The numerical results obtained by the PDD method agree well with the Monte Carlo simulation (MCS) method. The results of the PDD method can approximate to MCS better with the increasing of the polynomial order. Meanwhile, the Uniform-Legendre polynomials can eliminate perturbation of the PDD method to a certain extent via comparing it with the Gaussian-Hermite polynomials.     

LEONARDO DA VINCI AND FLUID MECHANICS 1)

旷世全才列奥纳多·达·芬奇(Leonardo da Vinci),被世人誉为画家、雕刻家、天文学家、发明家、音乐家、数学家、解剖学家、生理学家、地质学家、植物学家、作家、军事、建筑工程和制图师,是意大利文艺复兴时期人文主义的代表人物。本文对其流体力学相关思想及湍流、飞行、波浪和风暴等几个方面的研究贡献进行梳理,认为他是流体力学科学研究的先驱和奠基人,也是一位“流体力学家”。     

海藻酸钙-壳聚糖微胶囊组成对BSA通透性能影响的研究

对海藻酸钙-壳聚糖微胶囊的牛血清白蛋白(BSA)双向通透性能进行了定量和定性的初步研究, 并初步考察了微胶囊的组成成分及海藻酸钠、壳聚糖的溶液浓度对BSA通透性能的影响. 结果表明海藻酸钙-壳聚糖微胶囊在pH 1.5～2.0时通透性减弱, pH 6.8时通透性增强, 且海藻酸钙微胶囊通透性大于海藻酸钙-壳聚糖微胶囊; 海藻酸钙-壳聚糖微胶囊中壳聚糖浓度越小, 通透性越好; 海藻酸钠浓度的影响不显著.