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61.
Xiao-Xu Ba Tian Gao Mian Yang Peng Jiang Feng-Lei Jiang Yi Liu 《Journal of solution chemistry》2020,49(1):100-116
As one of the newly emerged nanomaterials, graphene quantum dots (GQDs) have shown great application potential as tracking probes and drug carriers in biological areas. The GQDs synthesized via the nitric acid reflux method in this study turned out to quench the fluorescence of human serum albumin (HSA) and gamma globulin (γ-globulin) in two different functional ways. The fluorescence quenching effect of GQDs on HSA is a static pattern and the predominant interaction forces are hydrogen bonds and van der Waals forces. Distinct from HSA, the interaction between GQDs and γ-globulins belongs to dynamic quenching and is driven by electrostatic forces. Ultraviolet–visible (UV–vis) differential spectrometry and transient state fluorescence spectrometry were also utilized to further confirm their quenching types. Also, thermodynamics parameters, the enthalpy change (ΔH) and entropy change (ΔS) of reaction between GQDs and proteins were obtained through a series of calculations from the van’t Hoff equation. Furthermore, the effect of GQDs on the conformational structure of proteins was characterized by synchronous fluorescence spectra (SFS), three-dimensional (3D) fluorescence and circular dichroism (CD) spectra. In addition, the binding mechanism of GQDs with HSA and γ-globulins were proposed based on the obtained experimental results. The research on the reaction between GQDs with HSA and γ-globulins offers promising insight for the further application of nanomaterials in biomedical fields. 相似文献
62.
Fluorescent Coumarin–Artemisinin Conjugates as Mitochondria‐Targeting Theranostic Probes for Enhanced Anticancer Activities
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Dr. Xu Zhang Qian Ba Zhanni Gu Dr. Diliang Guo Prof. Yu Zhou Prof. Yungen Xu Prof. Hui Wang Prof. Deju Ye Prof. Hong Liu 《Chemistry (Weinheim an der Bergstrasse, Germany)》2015,21(48):17415-17421
Mitochondria‐targeting theranostic probes that enable the simultaneously reporting of and triggering of mitochondrial dysfunctions in cancer cells are highly attractive for cancer diagnosis and therapy. Three fluorescent mitochondria‐targeting theranostic probes have been developed by linking a mitochondrial dye, coumarin‐3‐carboximide, with a widely used traditional Chinese medicine, artemisinin, to kill cancer cells. Fluorescence images showed that the designed coumarin–artemisinin conjugates localized mainly in mitochondria, leading to enhanced anticancer activities over artemisinin. High cytotoxicity against cancer cells correlated with the strong ability to accumulate in mitochondria, which could efficiently increase the intracellular reactive oxygen species level and induce cell apoptosis. This study highlights the potential of using mitochondria‐targeting fluorophores to selectively trigger and directly visualize subcellular drug delivery in living cells. 相似文献
63.
利用扫描电子显微镜(SEM)和X射线能谱仪(EDS)对聚丙烯/聚氯乙烯(PP80/PVC20)二元体系,以及聚丙烯多单体接枝物[PP-g-(St-co-MMA)]/PP/PVC三元体系的相容性进行了研究。由X射线能谱微区分析得到了共混物中氯元素面分布图。对氯元素面分布进行了粒径分布统计和面积计算。实验结果表明:在PP80/PVC20共混物100份中加入6份PP-g-(St-co-MMA)增容剂时,增容效果最好;进一步增加PP-g-(St-co-MMA)含量时,PP/PVC的相容性反而降低。差示扫描量热仪(DSC)的实验结果也佐证了SEM和EDS的实验结果。 相似文献
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66.
Fatma Başak Aydemir Akın Günay Figen Öztoprak Ş. İlker Birbil Pınar Yolum 《Journal of Global Optimization》2013,57(2):499-519
This paper proposes the use of multiagent cooperation for solving global optimization problems through the introduction of a new multiagent environment, MANGO. The strength of the environment lays in its flexible structure based on communicating software agents that attempt to solve a problem cooperatively. This structure allows the execution of a wide range of global optimization algorithms described as a set of interacting operations. At one extreme, MANGO welcomes an individual non-cooperating agent, which is basically the traditional way of solving a global optimization problem. At the other extreme, autonomous agents existing in the environment cooperate as they see fit during run time. We explain the development and communication tools provided in the environment as well as examples of agent realizations and cooperation scenarios. We also show how the multiagent structure is more effective than having a single nonlinear optimization algorithm with randomly selected initial points. 相似文献
67.
In this work, we propose a scheme to realize a joint remote preparation of an arbitrary three-qubit state using six EPR-type pairs as the shared quantum resource. By determining the right measurement bases for the preparers and right ancilla-assisted unitary transformation/recovery operations for the receiver, our scheme applies to the most general case when all the coefficients of the state to be prepared and the EPR-type pairs are complex. The total success probability is found to be dependent only on the “smaller” coefficients of the EPR-type pairs shared between the receiver and one of the preparers. 相似文献
68.
Metin Başarır Selma Altundağ Mustafa Kayıkçı 《Rendiconti del Circolo Matematico di Palermo》2010,59(2):277-287
The purpose of the paper is to introduce the concepts of almost λ-statistical convergence and strongly almost λ-convergence of sequences of fuzzy numbers. We establish some connections between these concepts. It is also shown that if
a sequence of fuzzy numbers is strongly almost λ-convergent with respect to a sequence of Orlicz funtions then it is almost λ-statistical convergent. 相似文献
69.
Chord length distributions interpretation using a polydispersed population: Modeling and experiments
A. Cameirao H. Le Ba M. Darbouret J.-M. Herri J.-L. Peytavy P. Glénat 《Journal of Crystal Growth》2012,342(1):65-71
Chord length distributions were measured during the crystallization of gas hydrates in a flow loop. The conditions on the flow loop were similar with the conditions in the marine pipelines. The flow loop was filled with water in oil emulsion and pressurized with methane (7 MPa) at low temperature (277 K). During crystallization water droplets crystallize and agglomerate. The CLD measures were interpreted in a preceding work [Le Ba et al., 2010] [1] by constructing random aggregates with known geometrical proprieties from a monodispersed population of droplets and calculating their CLD. Comparing calculated CLD with CLD from the experiment, the geometrical parameters: number of primary particles and fractal dimension of experimental aggregates are identified. However some differences remained between the experiment and the calculated CLD. In the present work the droplets population was considered polydispersed improving the comparison between the model and the experiment. 相似文献
70.
Dang van Ba 《Zeitschrift für Angewandte Mathematik und Physik (ZAMP)》1969,20(4):599-602
Résumé On essaie de trouver l'équation du mouvement de la barre de contrôle d'un réacteur en théorie ponctuelle à un groupe de neutrons retardés à partir des principes stochastiques. 相似文献