Labeling of Polymer Nanostructures for Medical Imaging: Importance of crosslinking extent, spacer length, and charge density

Radiolabeling studies were employed to investigate the influence of structure on the efficiency of surface functionalization for poly(acrylic acid)-coated shell crosslinked nanoparticles (SCKs) with two types of amine-terminated DOTA chelators. An intricate interplay between the chemical and physical properties of both the DOTA derivative and the SCK nanostructures was revealed, demonstrating the importance of structural control.     

A continuous–discontinuous second‐order transition in the satisfiability of random Horn‐SAT formulas

We compute the probability of satisfiability of a class of random Horn‐SAT formulae, motivated by a connection with the nonemptiness problem of finite tree automata. In particular, when the maximum clause length is three, this model displays a curve in its parameter space, along which the probability of satisfiability is discontinuous, ending in a second‐order phase transition where it is continuous but its derivative diverges. This is the first case in which a phase transition of this type has been rigorously established for a random constraint satisfaction problem. © 2007 Wiley Periodicals, Inc. Random Struct. Alg., 2007     

Monaural envelope correlation perception, revisited: effects of bandwidth, frequency separation, duration, and relative level of the noise bands

This article presents the results of two experiments investigating performance on a monaural envelope correlation discrimination task. Subjects were asked to discriminate pairs of noise bands that had identical envelopes (referred to as correlated stimuli) from pairs of noise bands that had envelopes which were independent (uncorrelated stimuli). In the first experiment, a number of stimulus parameters were varied: the center frequency of the lower frequency noise band in a pair, f1; the frequency separation between component noise bands; the duration of the stimuli; and the bandwidth of the component noise bands. For a long stimulus duration (500 ms) and a relatively wide bandwidth (100 Hz), subjects could easily discriminate correlated from uncorrelated stimuli for a wide range of frequency separations between the component noise bands. This was true both when f1 was 350 Hz, and when f1 was 2500 Hz. In each case, narrowing the bandwidth to 25 Hz, or shortening the duration to 100 ms, or both, made the task more difficult, but not impossible. In the second experiment, the level of the higher frequency noise band in a pair was varied. Performance did not decrease monotonically as the level of this band was decreased below the level of the other band, and only showed marked impairment when the level of the higher frequency band was at least 60 dB below that of the lower frequency band. The pattern of results in these two experiments is different from that which is obtained when the same stimulus parameters are varied in experiments investigating comodulation masking release (CMR). This suggests that the mechanisms underlying CMR and those underlying the discrimination of envelope correlation are not identical.     

Mass measurements of neutron-deficient nuclides close to A = 80 with a Penning trap

The masses of ^{80, 81, 82, 83}Y, ^{83, 84, 85, 86, 88}Zr and ^{85, 86, 87, 88}Nb have been measured with a typical precision of 7keV by using the Penning trap setup at IGISOL. The mass of ⁸⁴Zr has been measured for the first time. These precise mass measurements have improved S_p and Q_EC values for astrophysically important nuclides.     

Decrement detection in normal and impaired ears.

The smallest detectable duration of a brief decrement in the intensity of wideband noise was measured as a function of the depth of the decrement. In the first experiment, conditions were tested in which the noise before the decrement was more intense than the noise after the decrement, and vice-versa. These data were used to estimate the shape of an intensity-weighting function, or temporal window, describing the temporal resolution of the ear. The equivalent rectangular durations (ERDs) of the temporal windows measured in this way had values of about 5.5, 4.6, and 6.6 ms for noise spectrum levels of 10, 30, and 50 dB, respectively. In a second experiment, decrement detection was measured in subjects with unilateral sensorineural hearing loss. One set of thresholds was measured in the impaired ear, and two sets of thresholds were measured in the normal ear; one with the noise level at equal SPL to the level in the impaired ear, and one with the noise at equal SL. Temporal window shapes were also estimated from these data. Only one of the subjects showed reduced temporal resolution in the impaired ear, the other two subjects having similar ERD values for all three conditions.     

Simplex equations and their solutions

We investigate ann-simplex generalization of the classical and quantum Yang-Baxter equation. For the case ofsl(2) we find the most general solution of the classicaln-simplex equation for alln. These classical solutions can be quantized (in the sense of quantum group theory) forn=2,3 and we exhibit a quantum solution to the tetrahedron equations (n=3). The classical nondegenerate solutions cannot be quantized forn=4.     

Cavity nonlinear optics at low photon numbers from collective atomic motion

We report on Kerr nonlinearity and dispersive optical bistability of a Fabry-Perot optical resonator due to the displacement of ultracold atoms trapped within. In the driven resonator, such collective motion is induced by optical forces acting upon up to 10(5) 87Rb atoms prepared in the lowest band of a one-dimensional intracavity optical lattice. The longevity of atomic motional coherence allows for strongly nonlinear optics at extremely low cavity photon numbers, as demonstrated by the observation of both branches of optical bistability at photon numbers below unity.     

Stokes flow solutions in infinite and semi-infinite porous channels

We derive a class of exact solutions for Stokes flow in infinite and semi-infinite channel geometries with permeable walls. These simple, explicit, series expressions for both pressure and Stokes flow are valid for all permeability values. At the channel walls, we impose a no-slip condition for the tangential fluid velocity and a condition based on Darcy's law for the normal fluid velocity. Fluid flow across the channel boundaries is driven by the pressure drop between the channel interior and exterior; we assume the exterior pressure to be constant. We show how the ground state is an exact solution in the infinite channel case. For the semi-infinite channel domain, the ground-state solutions approximate well the full exact solution in the bulk and we derive a method to improve their accuracy at the transverse wall. This study is motivated by the need to quantitatively understand the detailed fluid dynamics applicable in a variety of engineering applications including membrane-based water purification, heat and mass transfer, and fuel cells.