A Nonclinical Spectroscopic Approach for Diagnosing Covid-19: A Concise Perspective

Journal of Applied Spectroscopy - With the COVID-19 outbreak, many challenges are posed before the scientific world to curb this pandemic. The diagnostic testing, treatment, and vaccine development...     

A three-component cyclocondensation reaction for the synthesis of new triazolo[1,5-a]pyrimidine scaffolds using 3-aminotriazole,aldehydes and ketene N,S-acetal

Molecular Diversity - This study describes the use of 3-aminotriazole, different aldehydes and N-methyl-1-(methylthio)-2-nitroethenamine as a ketene N,S-acetal in a three-component condensation for...     

Principle of massive support in the opposed anvil high pressure apparatus

The Bridgman anvil technique offers a simple and versatile means of generating very high pressures required in solid state studies. The opposed anvil technique is based on the principle of massive support. The practical case of a gasketted anvil is considered, and an expression for the maximum pressure generated under massive support is derived in terms of the geometric parameters, the strength of the anvil material and the gasket properties. In particular, for a given maximum pressure, it is possible to calculate the taper angle, the taper height and the gasket thickness from this expression. The anvil is assumed to be in the elastic region under load. Good agreement is obtained between the calculated and the experimental values for the massive support factor (msf) for various taper angles. By choosing the proper geometry, it is possible to achieve a pressure as high as 130 kbar in an alloy steel anvil. It has been clearly found that the straight portion, where the taper ends, does not really take any part in changing the stress pattern. Thus the minimum straight portion can serve the purpose, and will result in material saving. Anvils exhibit yielding at very high pressure. It is also pointed out that a further strengthening of the anvil can extend the ultimate pressure. Several methods of further strengthening the anvils are discussed.