Stark's conjecture over complex cubic number fields

Systematic computation of Stark units over nontotally real base fields is carried out for the first time. Since the information provided by Stark's conjecture is significantly less in this situation than the information provided over totally real base fields, new techniques are required. Precomputing Stark units in relative quadratic extensions (where the conjecture is already known to hold) and coupling this information with the Fincke-Pohst algorithm applied to certain quadratic forms leads to a significant reduction in search time for finding Stark units in larger extensions (where the conjecture is still unproven). Stark's conjecture is verified in each case for these Stark units in larger extensions and explicit generating polynomials for abelian extensions over complex cubic base fields, including Hilbert class fields, are obtained from the minimal polynomials of these new Stark units.

     

On Certain Perturbations of the Erdös–Renyi Random Graph

We study perturbations of the Erdös–Renyi model for which the statistical weight of a graph depends on the abundance of certain geometrical patterns. Using the formal correspondance with an exactly solvable effective model, we show the existence of a percolation transition in the thermodynamical limit and derive perturbatively the expression of the threshold. The free energy and the moments of the degree distribution are also computed perturbatively in that limit and the percolation criterion is compared with the Molloy–Reed criterion.     

Solutions of the WDVV Equations and Integrable Hierarchies of KP Type

We show that reductions of KP hierarchies related to the loop algebra of SL_n with homogeneous gradation give solutions of the Darboux-Egoroff system of PDE's. Using explicit dressing matrices of the Riemann-Hilbert problem generalized to include a set of commuting additional symmetries, we construct solutions of the Witten– Dijkgraaf–E. Verlinde–H. Verlinde equations.     

On Guerra's broken replica-symmetry bound

Consider a random Hamiltonian $\text{H}{}_{\mathrm{N}}\text{(}\text{σ}\text{→}\text{)}$ for $\text{σ}\text{→}\text{∈Σ}{}_{\mathrm{N}}\text{={0,1}}{}^{\mathrm{<mtext>N</mtext>}}\text{.}$ We assume that the family $\text{(H}{}_{\mathrm{N}}\text{(}\text{σ}\text{→}\text{))}$ is jointly Gaussian centered and that for $\text{σ}\text{→}{}^1\text{,}\text{σ}\text{→}{}^2\text{∈Σ}{}_{\mathrm{N}}\text{,}$$\text{N}{}^{\mathrm{?1}}\text{EH}{}_{\mathrm{N}}\text{(}\text{σ}\text{→}{}^1\text{)H}{}_{\mathrm{N}}\text{(}\text{σ}\text{→}{}^2\text{)}$ =ξ(N^?1∑_i?Nσ¹_iσ²_i) for a certain function ξ on $\text{R}$. F. Guerra proved the remarkable fact that the free energy of the system with Hamiltonian $\text{H}{}_{\mathrm{N}}\text{(}\text{σ}\text{→}\text{)+h∑}{}_{\mathrm{i?N}}\text{σ}{}_{\mathrm{i}}$ is bounded below by the free energy of the Parisi solution provided that ξ is convex on $\text{R}$. We prove that this fact remains (asymptotically) true when the function ξ is only assumed to be convex on $\text{R}{}^{\mathrm{+}}$. This covers in particular the case of the p-spin interaction model for any p. To cite this article: M. Talagrand, C. R. Acad. Sci. Paris, Ser. I 337 (2003).     

(Systemic) phototoxicity of drugs and other xenobiotics.

Xenobiotics extensively used in drugs, cosmetics, food and agricultural chemicals can produce adverse biological effects. These toxic effects are separated into classes, e.g. hepatotoxicity, genotoxicity and neurotoxicity. Skin allergy, part of immunotoxicity, is also a subdivision of toxicology. When light is an essential condition for toxicity, the xenobiotic is called phototoxic. Thus it fits into the logic of toxicology that photoallergic compounds are a subdivision of phototoxic compounds. Phototoxicons as a group do not differ from the group of phototherapeutics with regard to their eventual biological effects. The primary photoreactions, secondary molecular processes, biomolecules involved and cellular and tissue damage are similar. The difference between the two groups is in the appreciation of the photobiological effects: adverse vs. desired. The aim of research is to determine the part of the molecular structure which makes a given compound phototoxic. With that knowledge the structure of the phototoxicon can be changed. This can result in a derivative which still has the desired properties of the parent compound, but is no longer phototoxic. This aim can be reached by combining data from both in vitro and in vivo research. The variety and number of phototoxic compounds is large. This, together with the limited research effort devoted to this subject so far, means that for most phototoxic xenobiotics a relationship between structure and in vivo photoreactivity is not available. In this review, emphasis is placed on xenobiotics whose in vitro and in vivo photochemistry have been studied. Furthermore, possible phototoxic effects which do not concern the skin but involve inner organs (systemic effects) are considered. References in this review mostly concern investigations over the last 10 years. For older literature or for additional information, references to other reviews are given. Important groups of phototoxic xenobiotics not dealt with in this article were already sufficiently covered in the reviews referred to.