Maghemite/poly(<Emphasis Type="SmallCaps">d,l</Emphasis>-lactide-<Emphasis Type="Italic">co</Emphasis>-glycolyde) composite nanoplatform for therapeutic applications

A reproducible methodology is described for the synthesis, by following the double emulsion/solvent evaporation technique, of magnetic nanocomposites (average diameter ≈ 135 nm) consisting of maghemite nuclei and a biodegradable poly(d,l-lactide-co-glycolide) matrix. The heterogeneous structure of the nanoparticles can confer them the responsiveness to magnetic gradients, giving both the possibility of their use as a drug delivery system and adequate heating characteristics for a hyperthermia effect. The physical chemistry of the nanocomposites was extensively characterized, this establishing that their surface properties were similar to that of pure poly(d,l-lactide-co-glycolide). From an electrokinetic point of view, zeta potential determinations (as a function of the ionic strength, and pH) pointed out that the nanocomposites were almost indistinguishable from the copolymer. The surface thermodynamic analysis agreed with the electrophoretic one in suggesting that the coverage of the magnetic nuclei was complete, since the hydrophilic nature of maghemite was modified and the nanoparticles turned into hydrophobic, just like the copolymer, when they were embedded into poly(d,l-lactide-co-glycolide). The magnetic behaviours of the composite nanoparticles were also checked. Their heating properties were studied in vitro in a high-frequency alternating gradient of magnetic field: a stable maximum temperature of 47 °C was satisfactorily achieved within 45 min. Blood compatibility of the nanocomposites was also defined in vitro. To our knowledge, this is the first time that such kind of magnetic-sensitive nanoformulation with very promising characteristics (e.g. blood compatibility, magnetic drug targeting capabilities, and hyperthermia) has been developed for therapeutic purposes.     

The electrical conductivity of chloride melts

The interrelationship between electrical conductivity, molar volume and enthalpy of mixing was studied for molten chlorides and their mixtures. The dependence of electrical conductivity and activation energy on the molar volume is different for various groups of salts. The dependence of specific conductivity on molar volume obtained for molten alkali chlorides was found to be similar to other chloride salts. The specific conductivity of binary mixtures that lack strong chemical interactions between the components can also be described by the proposed empirical equation. The enthalpy of mixing should be taken into consideration for these chemical interactions.     

Geometric phase decomposition in the basis of Hermite-Gaussian functions

The work presents geometric phase decomposition for analytical signals using Hermite-Gaussian functions. The decomposition is based on the time-frequency distribution with reassigned and multi-tapered spectrogram resulting in increased phase estimation resolution. Numerical analysis is applied to a number of SU(2) evolutions, such as spin-1/2 particle in a static and rotating magnetic field, as well as polarization rotation of a plane wave in optically active medium. Geometric phase decomposition results are provided also for quantum harmonic oscillator and a radiation field of an electric dipole exited by a short pulse.     

A study on the effect of filling factor for laser action in dielectric random media

In a random system composed of dielectric materials, laser action is expected to occur from the light localization caused by multiple scattering and interference effect. The wavelengths at which the laser oscillation occurs in random media depend on the mean free path of continuous scattering. Since the mean free path of continuous scattering is dependent on the filling factor, it is important to investigate systematically the effect of the filling factor for the laser action. In the present study, we calculate the Poynting vectors of the light emitted from two-dimensional random media consisting of dielectric rods with population inversion modeled by the negative imaginary part of relative permittivity. The spectra of the radiated Poynting vectors from the two-dimensional random media are shown for several different filling factors and for various values of population inversion. We try to find laser generation which occurs at low population inversion and discuss about the threshold of laser action occurring in dielectric structures with different filling factors. We also study the spacial distribution of the electric field amplitude in several frequency regions where light strongly amplifies.     

Statistical Mechanics of a Simplified Bipartite Matching Problem: An Analytical Treatment

We perform an analytical study of a simplified bipartite matching problem in which there exists a constant matching energy, and both heterosexual and homosexual pairings are allowed. We obtain the partition function in a closed analytical form and we calculate the corresponding thermodynamic functions of this model. We conclude that the model is favored at high temperatures, for which the probabilities of heterosexual and homosexual pairs tend to become equal. In the limits of low and high temperatures, the system is extensive, however this property is lost in the general case. There exists a relation between the matching energies for which the system becomes more stable under external (thermal) perturbations. As the difference of energies between the two possible matches increases the system becomes more ordered, while the maximum of entropy is achieved when these energies are equal. In this limit, there is a first order phase transition between two phases with constant entropy.     

Analytic Perturbation Theory for Bound States in the Transfer Matrix Spectrum of Weakly Correlated Lattice Ferromagnetic Spin Systems

We consider general d-dimensional lattice ferromagnetic spin systems with nearest neighbor interactions in the high temperature region (β≪1). Each model is characterized by a single site apriori spin distribution taken to be even. We also take the parameter α=〈s ⁴〉−3〈s ²〉²>0, i.e. in the region which we call Gaussian subjugation, where 〈s ^k 〉 denotes the kth moment of the apriori distribution. Associated with the model is a lattice quantum field theory known to contain a particle of asymptotic mass −lnβ and a bound state below the two-particle threshold. We develop a β analytic perturbation theory for the binding energy of this bound state. As a key ingredient in obtaining our result we show that the Fourier transform of the two-point function is a meromorphic function, with a simple pole, in a suitable complex spectral parameter and the coefficients of its Laurent expansion are analytic in β.     

Magnetic response of split ring resonator metamaterials: From effective medium dispersion to photonic band gaps

On systematically investigating the electromagnetic response of periodic split-ring resonator (SRR) metamaterials as a function of the size-to-wavelength (a/λ) ratio, we find that the stop bands due to the geometric resonances of the SRR weaken with increasing (a/λ) ratio, and are eventually replaced by stop bands due to Bragg scattering. Our study traces the behaviour of SRR-based metamaterials as the resonance frequency increases and the wavelength of the radiation finally becomes comparable to the size of the unit cell of the metamaterial. In the intermediate stages, the dispersion of the SRR metamaterial can still be described as due to a localized magnetic resonances while Bragg scattering finally becomes the dominant phenomenon as a/λ∼1/2.     

Electrical and structural properties of poly (ethylene oxide)/silver triflate polymer electrolyte system dispersed with MgO nanofillers

Solvent-free films of poly (ethylene oxide)–silver triflate (PEO–AgCF₃SO₃)/MgO-based nanocomposite polymer electrolytes (PEO)₅₀AgCF₃SO₃–x wt.% MgO (x = 1, 3, 5, 7, and 10) obtained using solution casting technique were found to exhibit an appreciably good complexation of MgO nanofiller within the polymer electrolyte system and non-Debye type of relaxation as revealed by Fourier transform infrared and complex impedance analyses. Optimized filler (5 wt.% MgO) when incorporated into the polymer electrolyte resulted in a maximum electrical conductivity of 2 × 10⁻⁶ S cm⁻¹ in conjunction with a silver ionic transference number (t _Ag+) of 0.23 at room temperature (298 K). Detailed structural, thermal, and surface morphological investigation indicated a slight reduction in the degree of crystallinity owing to the addition of MgO nanofiller.     

Spring-block approach for crack patterns in glass

Fracture patterns resulting from point-like impact acting perpendicularly on the plane of a commercial sodalime glass plate is modelled by a spring-block system. The characteristic patterns consist of crack lines that are spreading radially from the impact point and concentric arcs intersecting these radial lines. Experimental results suggest that the number of radial crack lines is scaling linearly with the energy dissipated during the crack formation process. The elaborated spring-block model reproduces with success the observed fracture patterns and scaling law.     

Numerical study of the effect of gas flow in low pressure inductively coupled Ar/N<Subscript>2</Subscript> plasmas

The effect of gas flow in low pressure inductively coupled Ar/N₂ plasmas operating at the rf frequency of 13.56 MHz and the total gas pressure of 20 mTorr is studied at the gas flows of 5–700 sccm by coupling the plasma simulation with the calculation of flow dynamics. The gas temperature is 300 K and input power is 300 W. The Ar fractions are varied from 0% to 95%. The species taken into account include electrons, Ar atoms and their excited levels, N₂ molecules and their seven different excited levels, N atoms, and Ar⁺, N⁺, N₂ ⁺, N₄ ⁺ ions. 51 chemical reactions are considered. It is found that the electron densities increase and electron temperatures decrease with a rise in gas flow rate for the different Ar fractions. The densities of all the plasma species for the different Ar fractions and gas flow rates are obtained. The collisional power losses in plasma discharges are presented and the effect of gas flow is investigated.