Stereoselective Synthesis of δ-Selanyl Allylic Alcohols by Hydrozirconation of Propargyl Selenides

Hydrozirconation of propargyl selenides afford(E)-3-selanyl vinylzirconocenes chlorides 2.Intermediates 2 reacted with aldehydes to obtain δ-selanyl allylic alcohols.     

Further progress in atom transfer radical polymerizations conducted in a waterborne system

An improved atom transfer radical polymerization (ATRP) process was developed for use in a waterborne miniemulsion system. To conduct a successful ATRP in a heterogeneous waterborne system, it is of great importance to ensure control over the polymerization process while preserving colloidal stability. Efforts devoted to optimization of reaction conditions and improvement in the overall productivity of the process allowed the development of a novel, practical initiation system for ATRP suitable for use in a miniemulsion procedure that can provide copolymers of well-defined composition (e.g., block copolymers) and topologies (e.g., multiarm polymer). © 2003 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 41: 3606–3614, 2003     

Study on the Synthesis of Metabolite CM2 of Clausenamide

Synthesis of the optically active metabolite of clausenamide cm2(3,5-dihydroxy-5-(α-hydroxylbenzyl)-1-methyl-4-benzylpyrrolidin-2-one)from 3-O-acetyl-clausenamide was described.     

过渡金属氢化物和聚集双键化合物反应的研究Ⅲ.用ESR方法考察二茂锆氢化物与RNCS的反应机理

本文用ESR方法考察了Cp₂ZrH) Cl与RNCSR=C₆H₅,c-C₆H₁₁,n-C₄H₉)的反应的过程,结果表明,在这类反应过程中,Zr-H键发生均裂,中心金属锆经过+4-→+3-→+4的价态变化,反应通过自由基机理进行.     

导数示波极谱法测定废水中微量的对硝基苯乙酮

对硝基苯乙酮在０．０２５ｍｏｌ·Ｌ－１乙二胺－０．０１０ｍｏｌ·Ｌ－１ＥＤＴＡ底液中，产生一灵敏的极谱峰电流．峰电位为－０．３５Ｖ（ｖｓ．ＳＣＥ）．对硝基苯乙酮浓度在３．００×１０－８～１．００×１０－４ｍｏｌ·Ｌ－１范围内，浓度与峰电流成线性关系．检测限为３．００×１０－８ｍｏｌ·Ｌ－１．本方法用于氯霉素制药厂废水中的对硝基苯乙酮的测定，取得满意的结果     

NEW SYNTHETIC METHOD OF 4,4''''-OXYBIS(BENZOIC ACID)AND ITS APPLICATION IN POLYESTER

4,4'-Oxybis(benzoic acid)(Ⅰ)is an important monomer for making synthetic resin,heat resistant filmand liquid crystal fiber,etc.It has been synthesized either by the oxidation of 4,4'-dimethyl diphenylether,or by the electrophilic substitution of diphenyl ether,these substituents introduced into thebenzene ring can be further transformed into carboxylic groups.Diphenyl ethers are usually prepared fromphenols and halobenzenes through Ullmann resction.Due to the high reaction temerature(usually above200℃),long time heating and the formation of isomers,it is difficult to obtain pure products in highyields.     

Top介子在高能正负电子对撞机上的产生

在顶色辅助的人工色(TC2)模型框架下,研究了中性top介子和顶夸克的联合产生过程e+e–→ttπ0t.结果显示此过程的产生截面比标准模型和最小超对称标准模型中e+e–→ttH过程的产生截面都要大.在TC2模型合理的参数空间内,其产生截面可达20fb.通过此过程可在将来的对撞机上探测中性top介子.     

Modeling and optimizing a vendor managed replenishment system using machine learning and genetic algorithms

Using a supply chain network, we demonstrate the feasibility, viability, and robustness of applying machine learning and genetic algorithms to respectively model, understand, and optimize such data intensive environments. Deployment of these algorithms, which learn from and optimize data, can obviate the need to perform more complex, expensive, and time consuming design of experiments (DOE), which usually disrupt system operations. We apply and compare the behavior and performance of the proposed machine learning algorithms to that obtained via DOE in a simulated Vendor Managed Replenishment system, developed for an actual firm. The results show that the models resulting from the proposed algorithms had strong explanatory and predictive power, comparable to that of DOE. The optimal system settings and profit were also similar to that obtained from DOE. The virtues of using machine learning and evolutionary algorithms to model and optimize data rich environments thus seem promising because they are automatic, involving little human intervention and expertise. We believe and are exploring how they can be made adaptive to improve parameter estimates with increasing data, as well as seamlessly detecting system (and therefore model) changes, thus being capable of recursively updating and reoptimizing a modified or new model.     

干涉显微镜中相移误差分析

相移误差是影响干涉显微镜测量表面形貌精度的主要因素之一。介绍了四帧算法、五帧算法、四帧免疫算法、五帧免疫算法的原理和计算公式 ,并对其特点进行了分析比较。利用自行研制的带旋转检偏器的干涉显微测量系统 ,分别用四种算法对Ra=0 35μm和Ra=0 .0 9μm粗糙度样块进行了实测。结果表明 ,五帧算法的重复测量精度优于0 5nm ,五帧免疫算法的重复测量精度优于 0 3nm。同时对在普通干涉显微镜上进一步提高其测量精度做了初步探讨