Photoinduzierte umlagerung von isoxazolinen: Syntheseweg zu 2,4,5,8-Tetrahedron-1,3-dicx-5-azocinen

A high yield 2,4,5,8-tetrahydro-1,3-diox-5-azocine synthesis, which employs a sequence of cycloaddition and photoinduced rearrangement has been developed.     

A study of the direct spectrophotometric determination of uranium(VI) in trialkylamine extracts with 2-(5-bromo-2-pyridylazo)-5-diethylaminophenol

A straightforward spectrophotometric method is described for the determination of uranium(VI) in trialkylamine sulphate extracts in kerosene diluent; 2-(5-bromo-2-pyridylazo)-5-diethylaminophenol (Br-PADAP) is used for colour formation without resort to backextraction into an aqueous phase. The method provides good tolerance to sulphate ion and rapid colour development and appears to be free from interference when applied to extracts from uranium sulphate leach liquors.     

New alkaloids from Phoebe grandis (Nees) Merr

The alkaloidal extract of the leaves of Phoebe grandis (nees) merr. have provided two new minor alkaloids; phoebegrandine D (1), a proaporphine-tryptamine dimer, and phoebegrandine E (2), an indoloquinolizidine. This is the first report on the occurrence of an indoloquinolizidine in the Phoebe species. The crude extract also exhibited antiplasmodial activity (IC50<8 microg mL-1). The structures of the novel compounds were elucidated by spectroscopic methods, notably 2D NMR and HRMS.     

Bioactive eremophilanolides from Senecio poepigii

A new bioactive eremophilanolide, 1alpha-tigloyloxy-8betaH,10betaH-eremophil-7(11)-en-8alpha,12-olide, was isolated from Senecio poepigii and its structure was elucidated by spectral analysis. 1alpha-Angeloyloxy-8beta-methoxy-10betaH-eremophil-7(11)-en-8alpha,12-olide was also isolated. Antifungal and insect antifeedant properties were evaluated.     

Effect of concentration and particle size on nonlinearity of Au nano-fluid prepared by γ (Co) radiation

Nonlinear properties of Au nano-fluid prepared by γ-radiation method at different concentrations were investigated. Measurements of nonlinear refractive index and nonlinear absorption coefficient were carried out using a single beam Z-scan technique. A green CW laser beam operated at 532 nm was used as excitation source. The Au nano-fluid shows a good third order nonlinear response. The sign of the nonlinear refractive index is found to be negative and the magnitude is in the order of 10⁻⁷ cm²/W. This nonlinear effect increases as the concentration increases from 3.119 × 10⁻⁴ to 2.354 × 10⁻³ M which correspond to particle sizes of 4.0-30.5 nm, respectively. A good linear relationship was obtained between nonlinear refractive index and concentration. However the relationship between nonlinear refractive index and particle size was nonlinear behavior.     

Pulse-width modulation in defocused three-dimensional fringe projection

Shape measurements by fringe projection methods require high-quality sinusoidal fringes. We present a sinusoidal fringe generation technique that utilizes slightly defocused binary fringe projection. The proposed method is a spatial version of the well-known pulse-width modulation (PWM) technique of electrical engineering. PWM is easy to implement using off-the-shelf projectors, and it allows us to overcome the gamma problem (i.e., the nonlinear projector response) in the output light intensity. We will demonstrate that, with a small defocusing level--lower than with other techniques proposed in the literature--a high-quality sinusoidal pattern is obtained. Validation experiments using a commercial video projector are presented.     

Orientation effects on nitric acid dihydrate films

An investigation of orientation effects in films of nitric acid dihydrate (NAD) is presented, based on a systematic study of transmission and reflection-absorption infrared (RAIR) spectra of samples of varying thickness. The samples are prepared by vapor deposition on Ge (for transmission spectroscopy) and on Al substrates (for RAIR spectroscopy) at 175 K to produce crystalline alpha-NAD films. Transmission spectra were recorded at normal incidence, and RAIR spectra were recorded at a grazing angle of 75 degrees, with polarized radiation. The observed spectra are compared with predictions of a classical Fresnel model, to test the available optical indices of NAD, which are of great importance for the accurate interpretation of data from remote sensing measurements. Whereas the procedure yields satisfactory results for transmission and s-polarized RAIR spectra, it is found that the agreement is not acceptable for p-polarized RAIR spectra. An explanation is suggested in terms of a preferential alignment of the films, with the (10-1) crystallographic plane of the crystal situated parallel to the substrate. The infrared activity of a band at approximately 1170 cm(-1) is explained in terms of a preferential orientation of the crystal domains in the film.     

Leptoquark effects on ν τ propagation in the Earth

The proposal of pilgrim dark energy is based on the idea that phantom dark energy possesses enough resistive force to preclude black hole formation. We work on this proposal by choosing an interacting framework with cold dark matter and three cutoffs such as Hubble as well as event horizon and conformal age of the universe. We present a graphical analysis and focus our study on the pilgrim dark energy as well as interacting parameters. It is found that these parameters play an effective role on the equation of state parameter for exploring the phantom region of the universe. We also make the analysis of ω–ω′ and point out freezing region in the ω–ω′ plane. Finally, it turns out that the ΛCDM is achieved in the statefinders plane for all models.     

Enzymatic inhibitory activity of Ficus deltoidea leaf extract on matrix metalloproteinase-2, 8 and 9

Dysregulation of matrix metalloproteinases (MMPs) activity is known in many pathological conditions with which most of the conditions are related to elevate MMPs activities. Ficus deltoidea (FD) is a plant known for its therapeutic properties. In order to evaluate the therapeutic potential of FD leaf extract, we study the enzymatic inhibition properties of FD leaf extract and its major bioactive compounds (vitexin and isovitexin) on a panel of MMPs (MMP-2, MMP-8 and MMP-9) using experimental and computational approaches. FD leaf extract and its major bioactive compounds showed pronounced inhibition activity towards the MMPs tested. Computational docking analysis revealed that vitexin and isovitexin bind to the active site of the three tested MMPs. We also evaluated the cytotoxicity and cell migration inhibition activity of FD leaf extract in the endothelial EA.hy 926 cell line. Conclusively, this study provided additional information on the potential of FD leaf extract for therapeutical application.