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61.
A simple and robust method for determining the relative orientations of covalently linked protein domains using conjoined rigid body/torsion angle dynamics simulated annealing on the basis of residual dipolar couplings is presented. In this approach each domain is treated as a rigid body and the relevant degrees of conformational freedom are restricted to the backbone torsion angles (phi, psi) of the linker between the domains. By this means translational information afforded by the presence of an intact linker is preserved. We illustrate this approach using the domain-swapped dimer of the HIV-inactivating protein cyanovirin-N as an example.  相似文献   
62.
We study limit distribution of partial sums SN,k(t) = s = 1 [N t] Ak(Xs) of Appell polynomials of the long-range dependent moving average process Xt> = i t bt - i i, where {i} is a strictly stationary and weakly dependent martingale difference sequence, and bi id - 1 (0 < d < 1/2). We show that if k(1-2 d)<1, then suitably normalized partial sums SN,k(t) converge in distribution to the kth order Hermite process. This result generalizes the corresponding results of Surgailis, and Avram and Taqqu obtained in the case of the i.i.d. sequence { i}.  相似文献   
63.
Marius Crainic 《K-Theory》1999,17(4):319-362
We give a general method for computing the cyclic cohomology of crossed products by étale groupoids, extending the Feigin–Tsygan–Nistor spectral sequences. In particular we extend the computations performed by Brylinski, Burghelea, Connes, Feigin, Karoubi, Nistor, and Tsygan for the convolution algebra C c (G) of an étale groupoid, removing the Hausdorffness condition and including the computation of hyperbolic components. Examples like group actions on manifolds and foliations are considered.  相似文献   
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We consider the linearized version of the stationary Navier-Stokes equations on a subdomain of a smooth, compact Riemannian manifold M. The emphasis is on regularity: the boundary of is assumed to be only C1 and even Lipschitz, and the data are selected from appropriate Sobolev-Besov scales. Our approach relies on the method of boundary integral equations, suitably adapted to the variable-coefficient setting we are considering here. Applications to the stationary, nonlinear Navier-Stokes equations in this context are also discussed.  相似文献   
67.
We prove the well-posedness of the transmission problem for the Laplacian across a Lipschitz interface, with optimal non-tangential maximal function estimates, for data in Lebesgue and Hardy spaces on the boundary. As a corollary, we show that the spectral radius of the (adjoint) harmonic double layer potential K∗ in is less than , whenever is a bounded convex domain and 1<p?2.  相似文献   
68.
Albota MA  Wong FN 《Optics letters》2004,29(13):1449-1451
We demonstrate efficient single-photon detection at 1.55 microm by means of sum-frequency mixing with a strong pump at 1.064 microm in periodically poled lithium niobate followed by photon counting in the visible region. This scheme offers significant advantages over existing InGaAs photon counters: continuous-wave operation, higher detection efficiency, higher counting rates, and no afterpulsing. We achieved single-photon upconversion efficiency of 90% at 21.6 W of circulating power in a resonant pump cavity with a 400-mW Nd:YAG laser. We observed high background counts at strong circulating pump powers due to efficient upconversion of pump-induced fluorescence photons.  相似文献   
69.
With “hat” denoting the Banach envelope (of a quasi-Banach space) we prove that if 0<p<1, 0<q<1, ℝ, while if 0<p<1, 1≤q<+∞, ∝, and if 1≤p<+∞, 0<q<1, ℝ. Applications to questions regarding the global interior regularity of solutions to Poisson type problems for the three-dimensional Lamé system in Lipschitz domains are presented.  相似文献   
70.
Hydroxyapatite thin films were grown on layered structures by Pulsed Laser Deposition with the goal of investigating the interface of the ceramic film with the substrate. The latter consisted of Si/TiN/Ti sandwich structures. This multilayer substrate was also prepared by laser ablation earlier in the same experimental session.This particular type of structure was chosen in order to induce the in situ growth of hydroxyapatite directly onto freshly deposited Ti. We tried this way to avoid previous direct Ti exposure to air, hence its oxidation. The subsequent depositions of multilayers were performed with the aid of a carousel multi-target system mounted inside the irradiation chamber. This allowed for selecting in order the respective TiN, Ti and HA targets without opening the chamber between individual depositions.X-ray diffractometry, transmission electron microscopy and selected area electron diffractometry studies revealed the formation at the interface of a transition complex phase, 2 to 25 nm thick, consisting of a mixture of TiO2 and CaP phase. The specific growth of TiN and Ti phases was also investigated.  相似文献   
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