Synthesis of New Thiazoles from α-Halohetaryl Ketones

Reactions of -bromoacetylphenoxathiin, -bromoacetylphenoxathiin 10,10-dioxide, or -bromoacetylthianthrene with certain p-(arylsulfonyl)thiobenzamides lead to the formation of the corresponding 2,4-disubstituted thiazoles. The new compounds were characterized through elemental analysis and spectral data (IR, ¹H NMR, and ¹³C NMR).     

Essential oils and their constituents: anticonvulsant activity

A literature-based survey of plants species and their essential oils with anticonvulsant activity was carried out. As results, 30 species belonging to 13 families and 23 genera were identified for their activities in the experimental models used for anticonvulsant drug screening. Thirty chemical constituents of essential oils with anticonvulsant properties were described. Information on these 30 species is presented together with isolated bioactive compound studies.