Impulsive inelastic scattering of O+(4S) by isotopic hydrogen molecules

We present experimental evidence that at relative energies above 10 eV the non-reactive inelastic scattering of O⁺ by H₂, D₂, and HD arises from impulsive elastic scattering of 0⁺ by individual H or D atoms. The relation of this impulsive non-reactive scattering to the reactive scattering from these systems is briefly discussed.     

Evaluation of chelation concentration and cation separation of actinides at ultra-trace levels in urine matrix

Summary The feasibility of measuring picogram levels of actinides in a urine matrix using ion chromatography coupled on-line to an inductively coupled plasma quadrupole mass spectrometer (IC-Q-ICPMS) was investigated. A chelation column for separation of matrix ions and preconcentration of the actinides was combined with a cation-exchange column for separation of the actinides. Sample preparation required simple addition of ammonium acetate to adjust the pH of the urine matrix. Spike solutions containing ²³² Th, ²³⁷Np, ²³⁸U, ²³⁹Pu, and ²⁴¹Am were added to undiluted urine, diluted urine (1 : 9) and water. Results showed that this approach enhanced the signal sensitivities of all the tested actinides over two orders of magnitude in the water matrix, while certain elements (especially Am) can still be effectively concentrated in undiluted urine.     

Simultaneous determination of sixteen major and minor elements in river sediments by energy-dispersive x-ray fluorescence spectrometry after fusion in lithium tetraborate glass

Fluvial sediments, including the NBS SRM-1645 Standard River Sediment, were fused in lithium tetraborate to form glass discs on which determinations of 16 elements (K, Ca, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Rb, Sr, Y, Zr and Pb) were obtained simultaneously at a single set of x-ray conditions by energy-dispersive x-ray fluorescence spectrometry (e.d.x.r.f.). Relatively high sample-to-flux ratios of 1:3 were employed to obtained determinations of several minor as well as major elements on a single disc. Lower sample concentrations 1:6 and 1:10 were also used with the NBS SRM-1645. Inter-element corrections for absorption by iron were significant for detectable elements heavier than iron. In the NBS SRM-1645 samples, corrections were made for the fluorescence of chromium by the Fe K lines as well as the absorption of the Fe K lines by chromium. A background correction was also necessary for manganese in NBS SRM-1645. At the lowest sample-to-flux ratio (1:10) good agreement was obtained between the e.d.x.r.f. determinations and the NBS values for all quantifiable elements except zinc. At higher sample-to-flux ratios, agreement with the NBS values was generally poorer with increasing sample concentration. The relative standard deviation (RSD) of the eight quantifiable major and minor elements (K, Ca, Ti, Mn, Fe, Zn, Sr and Zr) determined under a single set of x-ray conditions ranged from 2 to 9% (RSD) with a mean RSD of 4.4% for a set of replica discs fused with Lake Pueblo/Arkansas River sediment samples.     

Suzuki-Miyaura approach to JNJ-26076713, an orally active tetrahydroquinoline-containing alphaVbeta3/alphaVbeta5 integrin antagonist. enantioselective synthesis and stereochemical studies

An improved scale-up synthesis was required for the alpha(V)beta(3)/alpha(V)beta(5) integrin antagonist 1, which had demonstrated oral efficacy in eye disease models of angiogenesis and vascular permeability. A stereodefined, quinoline-substituted, unsaturated ester was conveniently prepared by a Suzuki-Miyaura coupling to facilitate exploration of multiple methods of asymmetric reduction. The catalytic chiral hydrogenation of the corresponding unsaturated acid (Z-5b) with a ruthenium-based metal precursor and the (R)-XylPhanePhos ligand proved particularly efficient and economical. The resulting (3S)-quinoline-containing intermediate was reduced to an equal mixture of tetrahydroquinoline diastereomers. The undesired diastereomer could be recycled to the desired one by an oxidation/reduction protocol. The absolute stereochemistry of 1 was established as 3S,3'S by a combination of X-ray diffraction and chemical means.     

Height in splittings of hyperbolic groups

SupposeH is a hyperbolic subgroup of a hyperbolic groupG. Assume there existsn > 0 such that the intersection ofn essentially distinct conjugates ofH is always finite. Further assumeG splits overH with hyperbolic vertex and edge groups and the two inclusions ofH are quasi-isometric embeddings. ThenH is quasiconvex inG. This answers a question of Swarup and provides a partial converse to the main theorem of [23].     

A Combination Theorem for Metric Bundles

We introduce the notion of metric (graph) bundles which provide a coarse-geometric generalization of the notion of trees of metric spaces a la Bestvina?CFeighn in the special case that the inclusions of the edge spaces into the vertex spaces are uniform coarsely surjective quasi-isometries. We prove the existence of quasi-isometric sections in this generality. Then we prove a combination theorem for metric (graph) bundles that establishes sufficient conditions, particularly flaring, under which the metric bundles are hyperbolic. We use this to give examples of surface bundles over hyperbolic disks, whose universal cover is Gromov-hyperbolic. We also show that in typical situations, flaring is also a necessary condition.     

Surface impedance of a spatially dispersive medium

The surface impedance for non-normal specular reflection from a spatially dispersive medium is calculated using the additional boundary condition of vanishing polarization at the surface. There is no dependence on the longitudinal dielectric constant for either polarization directions of the electric field in contrast to the formula derived by Kliewer and Fuchs.     

Image potential from a free electron metal

We calculate the response of a free electron metal to a static charge Q located outside of the metal surface. We derive the electrostatic potential outside of the surface, inside of the surface, and the frequency response. Our derivation uses standard quantum mechanics, and the results are found exactly in the random phase approximation. Unlike prior calculations, which made approximations, our results do not agree with classical image theory.