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11.
Li Changjun; Li Zheng; Evans David J.; Zhang Tie 《IMA Journal of Numerical Analysis》2003,23(4):581-592
Golub et al. (2001, BIT, 41, 7185) gave a generalizedsuccessive over-relaxation method for the augmented systems.In this paper, the connection between the SOR-like method andthe preconditioned conjugate gradient (PCG) method for the augmentedsystems is investigated. It is shown that the PCG method isat least as accurate (fast) as the SOR-like method. Numericalexamples demonstrate that the PCG method is much faster thanthe SOR-like method. 相似文献
12.
Vikram S. Deshpande Milan Mrksich Anthony G. Evans 《Journal of the mechanics and physics of solids》2008,56(4):1484-1510
Focal adhesions (FAs) are large, multi-protein complexes that provide a mechanical link between the cytoskeletal contractile machinery and the extracellular matrix. They exhibit mechanosensitive properties; they self-assemble upon application of pulling forces and dissociate when these forces are decreased. We rationalize this mechano-sensitivity from thermodynamic considerations and develop a continuum framework in which the cytoskeletal contractile forces generated by stress fibers drive the assembly of the FA multi-protein complexes. The FA model has three essential features: (i) the low and high affinity integrins co-exist in thermodynamic equilibrium, (ii) the low affinity integrins within the plasma membrane are mobile, and (iii) the contractile forces generated by the stress fibers are in mechanical equilibrium and change the free energies of the integrins. A general two-dimensional framework is presented and the essential features of the model illustrated using one-dimensional examples. Consistent with observations, the coupled stress fiber and FA model predict that (a) the FAs concentrate around the periphery of the cell; (b) the fraction of the cell covered by FAs increases with decreasing cell size while the total FA intensity increases with increasing cell size; and (c) the FA intensity decreases substantially when cell contractility is curtailed. 相似文献
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Gerald W. Evans Robert Fairbairn 《The Journal of the Operational Research Society》1989,40(11):971-981
A 0-1 integer linear programme for the selection and scheduling of US National Aeronautics and Space Administration (NASA) missions over a long planning horizon is presented. This model was formulated to allow a higher-level user-interaction with an advanced missions database currently being developed. The model implicitly considers the multi-objective nature of the problem, which results from the desire to maximize benefits in several categories as well as from the desire to minimize cost. In addition, the model allows the planner much flexibility in the selection process. This is accomplished by allowing the planner the ability to specify long- or short-term budget constraints, precursor/follow-on mission requirements, or any number of other idiosyncratic constraints which might be of importance in the decision process. Small example problems are solved in order to illustrate the approach, and areas for further research are discussed. 相似文献
15.
The Dirac equation is solved for two novel terms which describe the interaction energy between the half-integral spin of a
fermion and the classical, circularly polarized, electromagnetic field. A simple experiment is suggested to test the new terms
and the existence of radiation-induced fermion resonance. 相似文献
16.
In many metrics of physical interest, the gravitational field can be represented as an optical medium with an effective index of refraction. We show that, in such a metric, the orbits of both massive and massless particles are governed by a variational principle which involves the index of refraction and which assumes the form of Fermat's principle or of Maupertuis's principle. From this variational principle we derive exact equations of motion of Newtonian form which govern both massless and massive particles. These equations of motion are applied to some problems of physical interest. 相似文献
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Kurt V. Schenker Wolfgang Von Philipsborn C. Anderson Evans Werner Skuballa Georg-Alexander Hoyer 《Helvetica chimica acta》1986,69(7):1718-1727
The configurations of the 5,6-double bond in the carbacyclins iloprost ( 3 ; (E)) and isoiloprost ( 4 ; (Z)) are based on a complete assignment of the 13C and 1H resonances determined by 1D and 2D 13C-NMR and 1H-NMR methods. 相似文献
20.
M. Jonathan Fray Paul Allen Paul R. Bradley Clare E. Challenger Michael Closier Tim J. Evans Mark L. Lewis John P. Mathias Carly L. Nichols Yvonne M. Po-Ba Hayley Snow Mark H. Stefaniak Hannah V. Vuong 《Tetrahedron》2006,62(29):6869-6875
The synthesis of ten substituted aminomethylene tetrahydro-isoquinolines is described, proceeding in eight steps from 5-hydroxyisoquinoline via reductive amination of N-Boc tetrahydro-isoquinoline 5-carboxaldehyde. Likewise, reductive amination was used to prepare four substituted dihydro-isoindoles from the corresponding aldehyde. The dihydro-isoindole ring system was conveniently accessed via a 2+2+2 cycloaddition reaction. 相似文献