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991.
992.
以甲醇作为溶剂,用紫外分光光度法测定氯氟吡氧乙酸十二酯的含量,测得氯氟吡氧乙酸十二酯对照品溶液浓度在12.0~20.0μg/mL范围之内线性关系良好,其线性方程为A=0.0815C+0.0318(R2=0.9832).平均回收率为90.86%,RSD为5.3%(n=6),结果说明方法简便、灵敏、准确,重现性好. 相似文献
993.
994.
Wang Y Dai Q Zou B Yu WW Liu B Zou G 《Langmuir : the ACS journal of surfaces and colloids》2010,26(24):19129-19135
In comparison to the previous lengthy approaches, we described a general and simple strategy for engineering the superlattice assembly of IV-VI semiconductor nanocrystals (NCs) with tunable sizes and morphologies. Not only the well-studied spherical NCs but also some special-shaped NCs, such as the quasi-cubic, cubic, truncated octahedral, and octahedral, could self-assemble into well-ordered patterns, as demonstrated in PbS, PbSe, and PbTe. These results extended our proposed model about the configuration of ligand chains in the superlattice assembly. This powerful capability of assembling superlattices was dominated by a heat-treatment process, providing a significant and extensive direction in the engineering of morphology-tunable NC superlattices. 相似文献
995.
Chen Z Chen W Yuan B Xiao L Liu D Jin Y Quan B Wang JO Ibrahim K Wang Z Zhang W Jiang X 《Langmuir : the ACS journal of surfaces and colloids》2010,26(23):17790-17794
This report establishes an in vitro model on glass surfaces for patterning multiple types of cells to simulate cell-cell interactions in vivo. The model employs a microfluidic system and poly(ethylene glycol)-terminated oxysilane (PEG-oxysilane) to modify glass surfaces in order to resist cell adhesion. The system allows the selective confinement of different types of cells to realize complete confinement, partial confinement, and no confinement of three types of cells on glass surfaces. The model was applied to study intercellular interactions among human umbilical vein endothelial cells (HUVEC), PLA 801 C and PLA801 D cells. 相似文献
996.
Jialei Liu Shuhui Bo Xinhou Liu Zhen Zhen 《Journal of inclusion phenomena and macrocyclic chemistry》2010,67(3-4):253-260
Naringenin is a flavonoid specific to citrus fruits and possesses anti-inflammatory, anticarcinogenic, and antitumour effects. But due to a lower half-life and rapid clearance from the body, frequent administration of the molecule is required. To improve the bioavailability and prolong its duration in body system, its phospholipid complexes were prepared by a simple and reproducible method. Naringenin was complexed with phosphatidylcholine in equimolar ratio, in presence of dichloromethane. The prepared Phytosomes (naringenin–phospholipid complex) were evaluated for various physical parameters like FT-IR spectroscopy, Differential Scanning Calorimetry (DSC), X-ray powder diffractometry (XRPD), Solubility, Scanning Electron Microscopy (SEM) and the in vitro drug release study. These phospholipid complexes of naringenin were found to be irregular and disc shaped with rough surface in SEM. Drug content was found to be 91.7% (w/w). FTIR, 1H NMR, DSC and XRPD data confirmed the formation of phospholipid complex. Water solubility of naringenin improved from 43.83 to 79.31 μg/mL in the prepared complex. Unlike the free naringenin (which showed a total of only 27% drug release at the end of 10 h), naringenin complex showed 99.80% release at the end of 10 h of dissolution study. Thus it can be concluded that the phospholipid complex of naringenin may be of potential use for improving bioavailability. 相似文献
997.
JPC – Journal of Planar Chromatography – Modern TLC - After much improvement of a new type of RP-18 sintered plate, mobile phase could be successfully used in planar... 相似文献
998.
Zhen Wang Yongmei Xu Bo Yang Gopinath Tiruchinapally Bin Sun Renpeng Liu Steven Dulaney Jian Liu Xuefei Huang 《Chemistry (Weinheim an der Bergstrasse, Germany)》2010,16(28):8365-8375
Heparin (HP) and heparan sulfate (HS) play important roles in many biological events. Increasing evidence has shown that the biological functions of HP and HS can be critically dependent upon their precise structures, including the position of the iduronic acids and sulfation patterns. However, unraveling the HP code has been extremely challenging due to the enormous structural variations. To overcome this hurdle, we investigated the possibility of assembling a library of HP/HS oligosaccharides using a preactivation‐based, one‐pot glycosylation method. A major challenge in HP/HS oligosaccharide synthesis is stereoselectivity in the formation of the cis‐1,4‐linkages between glucosamine and the uronic acid. Through screening, suitable protective groups were identified on the matching glycosyl donor and acceptor, leading to stereospecific formation of both the cis‐1,4‐ and trans‐1,4‐linkages present in HP. The protective group chemistry designed was also very flexible. From two advanced thioglycosyl disaccharide intermediates, all of the required disaccharide modules for library preparation could be generated in a divergent manner, which greatly simplified building‐block preparation. Furthermore, the reactivity‐independent nature of the preactivation‐based, one‐pot approach enabled us to mix the building blocks. This allowed rapid assembly of twelve HP/HS hexasaccharides with systematically varied and precisely controlled backbone structures in a combinatorial fashion. The speed and the high yields achieved in glycoassembly without the need to use a large excess of building blocks highlighted the advantages of our approach, which can be of general use to facilitate the study of HP/HS biology. As a proof of principle, this panel of hexasaccharides was used to probe the effect of backbone sequence on binding with the fibroblast growth factor‐2 (FGF‐2). A trisaccharide sequence of 2‐O‐sulfated iduronic acid flanked by N‐sulfated glucosamines was identified to be the minimum binding motif and N‐sulfation was found to be critical. This provides useful information for further development of more potent compounds towards FGF‐2 binding, which can have potential applications in wound healing and anticancer therapy. 相似文献
999.
From the whole plants of E. ritro L., the three new sesquiterpenoids (3α,4α,6α)‐3,13‐dihydroxyguaia‐7(11),10(14)‐dieno‐12,6‐lactone ( 1 ), (3α,4α,6α,11β)‐3‐hydroxyguai‐1(10)‐eno‐12,6‐lactone ( 2 ), and (11α)‐11,13‐dihydroarglanilic acid methyl ester (=(4β,6α,11α)‐4,6‐dihydroxy‐1‐oxoeudesm‐2‐en‐12‐oic acid methyl ester; 3 ), together with eight known sesquiterpenoids, were isolated. Their structures were elucidated through analysis of spectroscopic data including extensive 2D‐NMR. 相似文献
1000.
Wen‐Zuo Li Jian‐Bo Cheng Qing‐ Zhong Li Bao‐An Gong Jia‐Zhong Sun 《International journal of quantum chemistry》2010,110(10):1857-1862
The HBeN? and HNBe? anions have been investigated for the first time using the CASSCF, CASPT2, and DFT/B3LYP methods with the contracted atomic natural orbital (ANO) and cc‐pVTZ basis sets. The geometries of all stationary points along the potential energy surfaces were optimized at the CASSCF/ANO and B3LYP/cc‐pVTZ levels. The ground and the first excited states of HBeN? are predicted to be X2Π and A2Σ+ states, respectively. It was predicted that the ground state of HNBe? is X2Σ+ state. The A2Π state of HNBe? has unique imaginary frequency. A bend local minimum M1 was found along the 12A″ potential energy surface and the A2Π state of HNBe? should be the transition state of the isomerization reactions for M1 ? M1. The CASPT2/ANO potential energy curves of isomerization reactions were calculated as a function of HBeN bond angle. © 2009 Wiley Periodicals, Inc. Int J Quantum Chem, 2010 相似文献