偏瘫患者辅助下肢外骨骼设计与仿真分析

针对偏瘫患者外骨骼康复机器人降低外骨骼质量的要求,设计了一种辅助下肢外骨骼机器人,采用柔索驱动的膝关节,具有结构简单,质量轻的特点。同时利用ADAMS建立了外骨骼关节柔索驱动的动力学模型,绳索模块建立了柔索驱动模型,通过Ariel生物运动分析软件,采集髋、膝、踝关节运动数据,运用Spline函数进行了仿真分析。经过仿真分析柔索驱动在上台阶运动过程中的不同拉簧预紧力和拉簧刚度下传动特性和驱动力矩,为进一步研究设计下肢外骨骼提供依据。     

一种中药荧光指纹图谱的光谱图像构建方法

利用液晶光谱仪通过光谱成像法对黄柏和人参总皂甙进行了荧光光谱图像检测,采用滤波器与像素点定位联用的方法提取有效像素点,获取它们的荧光光谱图像,绘制了相应的中药荧光指纹图谱.结合欧氏距离的判定方法,将滤波器与像素点定位联用法、像素点优选法和背景差分算法所得的荧光指纹图谱进行比较,三种方法的差异由小到大的排序为滤波器与像素点定位联用法,背景差分算法,像素点优选法.说明滤波器与像素点定位联用法所得荧光指纹图谱稳定性最好,谱线最优.实验结果表明该方法可以用于构建中药荧光指纹图谱,从而提出了一种新的用于中药指纹图谱构建中提取有效像素点的可行方法.     

Composite lattice pattern formation in a wide-aperture thin-slice solid-state laser with imperfect reflective ends

We observed self-formations of multiple lasing channels and two-dimensional lasing patterns consisting of composite local modes having different lasing frequencies in a laser-diode-pumped wide-aperture thin-slice solid-state laser with imperfect reflective end surfaces. Global patterns resembling higher-order Hermite-Gaussian modes or possessing N-fold rotational symmetries were experimentally shown to appear due to the standard polished surface roughness of closely spaced reflective ends and nonlinear modal interactions.     

Discrimination of basal cell carcinoma from normal dermal stroma by quantitative multiphoton imaging

We performed multiphoton fluorescence (MF) and second-harmonic generation (SHG) imaging on human basal cell carcinoma samples. In the dermis, basal cell carcinomas can be identified by masses of autofluorescent cells with relatively large nuclei and marked peripheral palisading. In the normal dermis, SHG from dermal collagen contributes largely to the multiphoton signal. However, within the cancer stroma, SHG signals diminish and are replaced by autofluorescent signals, indicating that normal collagen structures responsible for SHG have been altered. To better delineate the cancer cells and cancer stroma from the normal dermis, a quantitative MF to SHG index is developed. We demonstrate that this index can be used to differentiate cancer cells and adjacent cancer stroma from the normal dermis. Our work shows that MF and SHG imaging can be an alternative for Mohs' surgery in the real-time guidance of the secure removal of basal cell carcinoma.     

Observation of a fused dual-fiber sensor head tips by SEM

The shape and microstructure of the fiber-optic liquid-level sensor head, which was made of two fusionspliced multimode optical fibers, were experimentally studied by using scanning electron microscope (SEM)technology in order to optimize the performance characteristic of the fiber sensor head. The parabolic profile of the sensor head was found to be better and having length-width ratio from 1.2:1 to 1.3:1. Some other useful possibilities were proposed.     

用自制仪器演示光通信

介绍一种新的小型演示仪器.该仪器用于普通物理光通信实验教学,能形象生动地演示光信号的耦合、传输、解调以及还原。仪器结构简单,思路清晰,可操作性强,对学生有很强的演示性。     

基于哈希理论和线性近邻传递反馈的乳腺X线图像肿块检索方法

在乳腺X线图像肿块检测中存在较高的假阳性率,通过基于内容的肿块检索,将待判定肿块与已确诊肿块进行相似性分析,可有效降低假阳性率.本文提出了一种结合可区分锚点图哈希和线性近邻传递的乳腺图像肿块检索方法.针对传统锚点图哈希在相似度定义中没有考虑病理相关性的问题,引入病理类别至锚点图哈希图像相似度计算,提出了可区分锚点图哈希以重新表示图像.利用线性近邻传递作为相关反馈技术,基于图像底层特征表达与图像高层语义间的学习机制,实现交互式肿块图像检索.采用北京大学人民医院乳腺中心提供的临床图像作为实验数据,实验结果表明,引入病理类别的可区分锚点图哈希图像表达在肿块相似性分析上优于传统锚点图哈希.相比于现有方法,本文提出的方法在肿块检索性能上得到明显提高.