Synthesis and Characterization of Novel Orange-emitting Iridium（Ⅲ） Complexes with Diphenylquinoline Ligands Containing Fluorinated Substituent

Three new cyclometalated iridium（m） complexes based on ligands of diphenylquinoline with fluorinated subsfituents were prepared, and characterized by elemental analysis （EA）, ^1H NMR, and mass spectroscopy （MS）. The photophysical and electrophosphorescent properties of the complexes were briefly discussed.     

The stereoselective synthesis of novel macrolide antibacterial agents via an intramolecular 1,3-dipolar cycloaddition of azomethine ylide

An intramolecular 1,3-dipolar cycloaddition of azomethine ylide, generated in situ via the reaction of C12-glycinate derivative of macrolide with formaldehyde, provided a novel tricyclic macrolide. The high stereoselectivity of this [2+3] reaction was achieved by introducing a suitable directing group at C-6 position of macrolide.     

Dynamic Study of Gemini Surfactant and Single-chain Surfactant at Air／Water Interface

Molecular dynamics (MD) simulation are used to study the properties of gemini surfactant of ethyl-α,ω-bis(dodecyldimethylammonium bromide) (C12C2C12) and dodecyl-trimethylammonium bromide (DTAB) at the air/water interface, respectively. In the two systems,t he surfactant concentrations are both 28 wt.%, and other conditions are also the same. After reaching the thermodynamic equilibrium, the concentration profiles, the radial distributions functions (RDF) and the mean squared displacement (MSD) are investigated. The results reveal that the surface activity of C12C2C12 surfactant is higher than DTAB surfactant.     

Circularly Polarized Absorption Property of Tetra-4[4''''-(2-methylbutoxy)benzoyloxy]phenyl Porphyrin by Introducing Optical Pendant Groups

Circularly polarized luminescent(CPL) materials possess special dissymmetric optical property, i.e. luminescent light having different intensities for left (L) and right(R) circularly polarized components. Recently, these materials have been applied in colour-image projection, stereoscopic displays and light-emitting diodes(LEDS)1-7. We have synthesized a new porphyrin derivative, tetra-4[4'-(2-methylbutoxy)benzoyloxy] phenyl porphyrin [T(MBBP)P], by introducing a chiral group, which p…     

七-O-乙酰基-β-乳糖异硫氰酸酯的合成、表征及电化学研究

本文合成了并培养出了七-O-乙酰基—β—乳糖异硫氰酸酯的单晶，用X射线衍射分析了其晶体结构。结果表明，晶体为正交晶系，P2₁2₁2₁空间群，a＝1．23282(7)，b＝1．80012(10)，c＝1.85230(10) nm，α＝β＝γ＝90°，V＝4．1107(4) nm³，Z＝4。电化学实验观测到单链DNA和双链DNA对该化合物的峰电流均有明显降低作用，表明化合物与DNA发生了静电作用。     

酸性品红与蛋白质结合反应的研究及应用

在pH1.4的Clark-Lubs缓冲介质中，蛋白质与酸性品红反应形成结合物，该结合物的最大吸收波长为576nm，与酸性品红相比，红移了34nm。据此拟定了分析方法，制定了牛血清白蛋白(BSA)、人血清白蛋白(HAS)、γ-球蛋白(γ-G)和酪蛋白的工作曲线，测定的摩尔吸光系数均在10^5数量级，用于人血清中总蛋白的测定，结果与溴甲酚绿(BCG)法基本一致。     

Synthesis of Thiourea Derivatives on Soluble Polymeric Support

A modified poly(ethylene glycol) (PEG) has been developed as the soluble polymeric supports for liquid phase synthesis of novel thiourea derivatives.In each step of the sequence,the PEG-bound products were precipitated in cold Et2O and the unreacted materials and by-products were removed by simple filtration.The progress of reaction,purity of the isolation and the structure of the PEG-bound products were easily monitored by TLC,IR and ^1H NMR spectra.Representative thiourea derivatives were obtained in moderate yields with excellent purity from this modified PEG-bound product by the cleavage with 50% TFA/H2O.     

氢部分选择性催化还原NO反应研究

在低钯含量活性非均布Pd/Al2O3催化剂上，实现了富氧条件下，氢部分选择性催化还原NO过程，低温、富氧条件下NO的转化率高达80％－100％。NO直接分解实验表明，600℃，NO分解转化率在无氧时为17．3％，有0．5％氧存在时接近于0。氢非选择性还原NO条件下，100℃以下，NO转化率为100％。根据实验结果及文献，推测了氢部分选择性还原NO过程中可能存在的反应，不同的反应温度下，NO脱除反应有所不同。在115℃以下，NO还原产物为NH3；115℃－155℃，NO还原产物为NH3、N2O和N2；155℃以上，NO还原产物中无NH3存在。NO还原反应与氢氧反应是平行的竞争反应。     

Fluorescence ratiometric pH sensor prepared from covalently immobilized porphyrin and benzothioxanthene

A fluorescence ratiometric sensor for pH determination is described in this paper. The sensor incorporated the pH-sensitive dye meso-5,10,15,20-tetra-(4-allyloxyphenyl)porphyrin (TAPP) as an indicator and a pH-insensitive dye N-(2-methacryloxyethyl)benzo[k,l]thioxanthene-3,4-dicarboximide (MBTD), a benzothioxanthene derivative, as a reference for fluorescence ratiometric measurement. To prevent leakage of the dyes, both were photocopolymerized with acrylamide, hydroxyethyl methacrylate, and triethylene glycol dimethacrylate on the silanized glass surface. The reproducibility and response time of the prepared sensor were sufficient. Most common coexisting inorganic ions and organic compounds did not interfere with pH sensing. In the acidic pH range from 1.5 to 5.0 the fluorescence intensity ratio of the two dyes varied linearly as a function of pH. The sensing membrane was found to have a lifetime of at least one month. The sensor was applied to the analysis of waste water and artificial samples.     

水杨醛肟铜络合物中性载体高选择性水杨酸根电极的研究

采用合成的Schiff碱金属络合物水杨醛肟铜(Ⅱ)、锌(Ⅱ)、镍(Ⅱ)为中性载体制备阴离子选择性电极。结果表明水杨醛肟铜(Ⅱ)对水杨酸根(Sal-)具有高选择性及优良的电位响应性能,电极呈现反Hofmeister选择性行为,其选择性次序为Sal->ClO4->SCN->I->NO2->NO3->Br->Cl->OAc->SO42-。采用交流阻抗技术和紫外可见光谱技术研究了电极的响应机理。该电极具有响应快、重现性好、检出限低和制备简单等优点。将电极用于药品及人体尿液分析,结果令人满意。