Bonding properties in organolithium aggregates

Results are given of the application of the CNDO/2 method to bonding in alkyllithium aggregates. Calculations relative to monomers and dim ers of methyl-, ethyl-, and vinyllithium, plus methyllithium tetramer are described.     

Studies of methoxymethyl-directed metalation

To explore the use of methoxymethyl groups to elaborate simple benzenoid precursors to more complex polyketide-derived natural products, the reaction of phenolmetoxymethyl ether $\text{ortho}$-anion was investigated with a number of electrophiles.     

The stereochemistry of cyclisation of n-t-butyldihydrocinnamamide to a β-lactam

Using a stereospecifically labelled precursor, the peroxide catalysed cyclisation of N-$\text{t}$-butyldihydrocinnamamide to the corresponding β-lactam was shown to proceed with complete loss of stereochemistry at the benzylic carbon atom.