Solvent‐dependent formation of inclusion complexes between methylated cyclodextrins and biodegradable polymers

The inclusion complexes (ICs) of unmodified natural and methylated α‐cyclodextrins (CDs) with biodegradable polymers, polyethylene glycol and poly(ε‐caprolactone), were prepared by two methods, that is, the one using water and the other using chloroform as the solvent for the respective CDs. The ICs obtained were characterized by IR, WAXD, DSC, and ¹³C CP/MAS NMR. It was found that the possibility and the phenomena of IC formation could be varied with the degree of methyl substitution of CD as well as the type of solvents used. Methylated α‐CDs showed the prominent characteristics of IC formation with polymers in the case where chloroform was used than in the case where water was used as the solvent for CDs, while vice versa in the case of native α‐CD. © 2008 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 46: 879–891, 2008     

Recurrence-Transience for Self-similar Additive Processes Associated with Stable Distributions

For any stable distribution on the line, recurrence-transience of the selfsimilar additive process {X _t ,t0} with (X ₁)= is determined. Comparison with the stable Lévy process {Y _t ,t0} with (Y ₁)= is made: if is not strictly stable, then {Y _t } is transient but {X _t } is recurrent except the obviously transient case of monotone sample functions.     

Studies and performance of decreased rail gap switch inductance byenhancing multichanneling via gas mixture

In pulsed power technology, a pressurized gap switch has been mainly utilized to produce a high power pulse. A multichannel rail gap switch has been widely utilized not only to obtain extremely low inductance, low resistance switching but also to reduce the damage of the electrode. A self-elected multichannel rail gap switch was developed. The switch was operated with pure SF₆ and the mixture of SF₆ with N₂, channel numbers of 20 and 100 were obtained with low switching inductance's of 15 nH and 9 nH, respectively     

Solid phase extraction of lead by Chelest Fiber Iry (aminopolycarboxylic acid-type cellulose)

Aminopolycarboxylic acid-type cellulose (Chelest Fiber Iry) has been studied for its sorption efficiencies with respect to lead from acidic solution. The influence pH and other properties related to sorption kinetic, isotherm, maximum capacity, stability and the mechanism of the sorption were discussed.Lead was quantitatively retained on the proposed adsorbent in the pH range of 2.5-5.5 (studied pH range 1.5-5.5). The maximum sorption capacity was found to be 0.86±0.06 mmol/g adsorbent. The decline in the efficiency of the adsorbent was not observed for repeated adsorption-desorption cycles. It was found that the preconcentration factor of 200 can be achieved. The limit of determination was found to be about 1 μg Pb/2 l. The method was applied to the determination of lead in water samples.     

Preparation of new nitrogen-bridged heterocycles 72. A new approach to 1-acyl-3-(substituted methylthio)thieno[3',4':4,5]imidazo[1,2-a]pyridine derivatives. [corrected

The alkaline treatment of the pyridinium salts, readily available from the S-alkylations of 3-amino-4-(1-pyridinio)thiophene-5-thiolates with various alkyl halides, in chloroform at room temperature afforded the corresponding thieno[3',4':4,5]imidazo[1,2-a]pyridine derivatives in low to moderate yields via the intramolecular cyclization of the resulting 1,5-dipoles followed by the aromatization of the primary cycloadducts. Interestingly, the reactions using unsymmetrical 3-amino-4-[1-(3-methylpyridinio)]thiophene-5-thiolates afforded only 8-methylthieno[3',4':4,5]imidazo[1,2-a]pyridines and the other 6-methyl derivatives were not formed at all. In addition the isolation of a byproduct in the condensation reaction of pyridinium salt with the solvent (CHCl?) is also discussed.     

Preparation of 3-bromo-2-methylfuran and 4-bromo-2-methylfuran

4-endo-5-exo-Dibromo-3-methyl-3,6-endo-oxyperhydrophthalic anhydride 3b and 4-exo-5-endo-dibro-mo-3-methyl-3,6-endo-oxyperhydrophtbalic anhydride 3c were isolated from the bromo-adducts of 3-methyl-3,6-endo-oxy-1,2,3,6-tetrahydrophthalic anhydride 2. When 3b or 3c was heated in quinoline, only 3-bromo-2-methylfuran 4 was obtained from 3b and only 4-bromo-2-methylfuran 5 from 3c.     

Attomole catechins determination by capillary liquid chromatography with electrochemical detection.

Attomole quantities of catechins were determined by a capillary liquid chromatography system with electrochemical detection (CLC-ECD) and the system is applied to the determination of catechins in human plasma. The eight catechins: catechin (C), epicatechin (EC), gallocatechin (GC), epigallocatechin (EGC), catechin gallate (Cg), epicatechin gallate (ECg), gallocatechin gallate (GCg), and epigallocatechin gallate (EGCg), were separated within 10 min using a capillary column (0.2 mm i.d.) and a mobile phase of phosphoric acid (85%)-methanol-water (0.5:27.5:72.5, v/v/v), and were detected at +0.85 V vs. Ag/AgCl. Peak heights were found to be linearly related to the amount of catechins injected, from 200 amol to 500 fmol (r > 0.998). The detection limits of the catechins were 61 amol for EGC, 75 amol for EC, 54 amol for GC, 61 amol for C, 67 amol for GCg, 75 amol for EGCg, 75 amol for ECg and 89 amol for Cg (S/N = 3). Because the present method is highly sensitive and allows facile pretreatment for plasma sample, the time courses of concentrations of catechins (GCg, EC, EGCg, ECg, and Cg) and their conjugates in human plasma obtained from a 10 microl plasma sample after ingestion of green tea could be determined.     

A short-step synthesis of naphtho[2,3-b]furan-4,9-dione

Phthalic anhydride in THF was added to 3-lithiofuran 2 in THF to give 3,3-di-(3-furyl)-1,3-dihy-droisobenzofuran-1-one 4 . On the other hand, 2 in THF was added to phthalic anhydride in THF to give 2-(3-furanoyl)benzoic acid 3 by the inverse addition method. Further, the parent naphtho[2,3-b]furan-4,9-dione 1 was obtained from the reaction of 3 with two equimolar amounts of LDA.     

Simultaneous measurement of velocity and pressure in a plane jet

A new technique was developed for the simultaneous measurement of velocity and pressure in turbulent flows. To accomplish this objective, a new probe (hereafter called the combined probe) that consists of an X-type hot-wire probe and a newly devised pressure probe was developed. The pressure probe was miniaturized by the MEMS fabrication process and by using a 0.1-in. microphone as a pressure sensor for improving the spatial resolution. This pressure probe was placed between two hot-wire sensors of which the X-type hot-wire probe was composed. The pressure probe was given a hemispherical tip, like that of a pitot tube, because an earlier pressure probe with a conical tip suffered from a reduction in spatial resolution. The spatial arrangement of the pressure probe and the hot-wire probe for the combined probe was carefully determined, because there was a risk that the measurement accuracy of one probe will be influenced by disturbances caused by the other probe when the two probes were placed very close to each other. Therefore, the combined probe was arranged to engender no noticeable interference between the velocity data and the pressure data measured by their respective probes. As one application of this combined probe, simultaneous measurements of pressure and two components of instantaneous velocity were performed in a plane jet. The turbulent energy budget and the cross-correlation coefficient of velocity and pressure in the intermittent region of the plane jet were estimated. The results show that the mean streamwise velocity, velocity fluctuation, and pressure fluctuation profiles were consistent with those measured individually using the X-type hot-wire probe or pressure probe. Moreover, it was shown that the integral value of the diffusion term (which should theoretically be equal to zero) in the turbulent energy transport equation was closer to zero than previous reports (Bradbury in J Fluid Mech 23(Part 1):31–64, 1965). In addition, the time variation of the cross-correlation coefficient in the intermittent region supports the vortex structure model predicted in previous studies (Browne et?al. in J Fluid Mech 149:355–373, 1984; Tanaka et?al. JSME Int J Ser B 49(4):899–905, 2006; Sakai et?al. J Fluid Sci Technol 2(3):611–622, 2007).