Synthesis,spectroscopic studies and biological screening of 18-membered octaazamacrocyclic complexes derived from acetonylacetone and thiocarbohydrazide

A series of the macrocyclic complexes is synthesized by condensation of acetonylacetone and thiocarbohydrazide in the presence of divalent metal salts in the methanolic medium. The complexes are of the type: [M(TML)X₂] where, M = Co(II), Ni(II), Cu(II), Zn(II) and Cd(II); X = Cl⁻ CH₃COO⁻ and TML is a tetradentate macrocyclic ligand. The complexes have been characterized with the help of various physicochemical techniques like elemental analyses, conductance measurements, magnetic measurements, NMR, infrared and electronic spectral studies. The low value of molar conductance indicates them to be non-electrolyte. On the basis of various studies a distorted octahedral geometry may be proposed for all the complexes. All the synthesized metal complexes were also tested for their in vitro antibacterial activities against some bacterial strains. The results obtained were compared with standard antibiotic: Ciprofloxacin. Some of the tested complexes shows good antibacterial activities against some bacterial strains.     

New Molybdaborane Clusters with a Bridged Phosphido Ligand

Abstract  

Treatment of [Cp*MoCl₄], 1 (Cp* = η⁵-C₅Me₅), with [LiBH₄.thf] in toluene at −40 °C, followed by thermolysis with [(thf)Li{CH(PPh₂–BH₃)₂}] results in the formation of a new class of phosphido bridged molybdaborane [(Cp*Mo)₂B₄H₇(μ-PPh₂)], 2 which has been characterized crystallographically. In addition, the above reaction also produces known [(Cp*Mo)₂B₅H₉], 3 and an unusual molybdaborane [(Cp*Mo)₂B₅H₈(O ⁱ Pr)], 4 ( ⁱ Pr = –CH(CH₃)₂). All the new compounds have been characterized in solution by ¹H, ¹¹B, ¹³C, ³¹P NMR spectroscopy and the structural types were unambiguously established by X-ray crystallographic analysis of compounds 2 and 4.     

ChemInform Abstract: Origin of the Unusual Stability of B12 and B13+ Clusters.

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