Effects of benzoyl group substituents on the mesomorphic properties of 5-alkoxy-2-benzoylaminotropones

Three types of 5-alkoxy-2-benzoylaminotropones, containing an electron-donating group and seven types of derivatives with electron-withdrawing groups on the benzoyl group, were prepared in order to study the thermal ranges of the mesophases exhibited. The troponoid amides had higher transition temperatures than the corresponding troponoid esters and benzenoid amides. From the ¹H NMR spectroscopic measurements and X-ray crystallographic analysis of 5-butoxy-2-(4-methoxybenzoylamino)tropone, it was observed that the benzoyl carbonyl group faced to the H-3 of the tropone ring to form an intramolecular hydrogen bond between the tropone carbonyl and the amide NH groups. The intramolecular hydrogen bonding of the troponoid amides made the molecules flat, inducing strong π-π intermolecular interactions between head-to-tail dimers and so reduced the possibility of intermolecular hydrogen bonding between the NH group and the carbonyl group of neighbouring molecules so decreasing melting points. Electron-donating groups enhanced the appearance of nematic phases while electron-withdrawing groups promoted smectic A phases.     

Relations between the Ruderman-Kittel-Kasuya-Yosida interaction electron concentration and crystal structure

The Ruderman-Kittel-Kasuya-Yosida interaction between localized magnetic spins on the basis of perfectly free conduction electron is calculated as a function of the Fermi wave vector of the conduction electrons. The expression of the interaction according to us converges rapidly, furthermore is strongly related to the detailed crystal structure. The q-dependence of exchange interaction j(q) between conduction- and localized magnetic electron is also taken into account. The result of the calculation is compared successfully with the change of magnetic structures, with θ_p and T_c or T_N of compounds having the CsCl structure, but less successfully with gadolinium compounds having the NaCl structure. These facts are discussed in conjunction with the difference of the RKKY interaction in the cscl and the NaCl structure.     

Higher homologues of cycloheptatriene,tropylium ion and oxepin : The demonstration of a diamagnetic and paramagnetic ring current in novel [15]annulene systems

Syntheses of 4,7:10,13-dioxido-cyclopentadecaheptaene (2.4.6.8.10.12.14) 8, 4,7:10,13-dioxido-cyclopentadecaheptaenyl tetrafluoroborate 10, and 1-oxa-4,7:10,13-dioxido-cyclopentadecaheptaene (2.4.6.8.10.12.14) 13 are described. As expected, the NMR spectrum of 10 exhibited a marked diamagnetic ring current, and that of 13 a paramagnetic ring current. These [15]annulenes 8, 10, and 13 are looked upon as the corresponding higher member of cycloheptatriene, tropylium ion, and oxepin, respectively.Attempted preparation of sulphur containing 1-thia[15]annulene was unsuccessful, presumably because of its increased antiaromatic character.     

Recognition of hepatotoxic homologues of Microcystin using a combination of selective adsorption media

Microcystin, a hepatotoxin produced by cyanobacteria, was chromatographically discriminated with newly prepared selective adsorption media. Since the name Microcystin refers to up to 70 different homologues, we have developed a novel technique to prepare selective recognition sites, based on the "Fragment Imprinting Effect". The homologues of Microcystin can be individually discriminated from each other by antigen-antibody assay as well as by C18-based HPLC. This is mainly due to differences in the three dimensional structure of Microcystin homologues; however, differences in toxicity are relatively small among the homologues. Therefore we have to measure the total amount of Microcystin homologues present to determine contamination by Microcystins. We have demonstrated the first group recognition for Microcystin homologues through combination of two different selective adsorption media prepared by a fragment imprinting technique.     

Target-selective ion-exchange media for highly hydrophilic compounds: a possible solution by use of the “interval immobilization technique”

We prepared a crosslinked polymer as a separation and/or adsorption medium for CYN, as shown in Fig. 1. The polymers were evaluated by high-performance liquid chromatography (HPLC) and adsorption was examined under batch conditions. Results from detailed HPLC evaluation and measurement of the difference between the binding affinity for CYN and for other compounds showed the prepared polymer had specific recognition ability for CYN.     

Chemistry of renieramycins. Part 4.synthesis of a simple natural marine product, 6-hydroxy-7-methoxyisoquinolinemethanol

6-Hydroxy-7-methoxyisoquinolinemethanol (15) and mimosamycin (1) were recently isolated from a marine sponge, Haliclona sp. The former was prepared in ten steps from vanillin (22) in 26% overall yield using an isopropyl for phenol protection.     

Segal-Bargmann transforms of one-mode interacting Fock spaces associated with Gaussian and Poisson measures

Let and denote the Gaussian and Poisson measures on , respectively. We show that there exists a unique measure on such that under the Segal-Bargmann transform the space is isomorphic to the space of analytic -functions on with respect to . We also introduce the Segal-Bargmann transform for the Poisson measure and prove the corresponding result. As a consequence, when and have the same variance, and are isomorphic to the same space under the - and -transforms, respectively. However, we show that the multiplication operators by on and on act quite differently on .