Synthesis of a new class of uridine phosphorylase inhibitors

A new series of potent uridine phosphorylase inhibitors have been prepared from barbituric acid. Among them, 1-[(2-hydroxyethoxy)methyl]-5-)(m--benzyloxy)benzylbarbituric acid ( 37 , BBBA) is the most promising having a K_i value of 1.1 ± 0.2 nM with uridine phosphorylase from human liver. The new inhibitors are easily synthesized and are better inhibitors of human uridine phosphorylase than their uracil counterparts.     

A covariant quasipotential operator for a composite system of two scaler particles

A quasipotential operator for a system of two scalar particles, and also an integral equation and a normalization condition for the wave function of the connected state, are obtained by the method of two-time Green's functions in an explicitly covariant form. The cases are considered of scalar and electromagnetic interactions of particles of the system.Frantsiska Skoriny Gomel' State University. Translated from Izvestiya Vysshikh Uchebnykh Zavedenii, Fizika, No. 6, pp. 112–118, June, 1993.     

Electronic and electromagnetic devices for millimeter-wave beam control arrays

Device alternatives for millimeter-wave beam control arrays are examined. For the control function, a wide range of semiconductor device as well as bulk material alternatives are considered. In addition, alternatives to the traditional metal strip are considered for the passive electromagnetic array element. This work should provide a broader perspective regarding the choices available for the optimized design of new beam control arrays.     

Spherical harmonic representation of the gravitational coupling between a truncated sector of a hollow cylinder and an arbitrary gravitational source: Relevance to the STEP experiment

The gravitational interaction between grooves machined in a hollow cylindrical mass of uniform density, and an external point mass, is derived in terms of the Associated Legendre functions, and the parametric form of the coupling coefficients is presented. The cross-sections of the grooves, which are regularly spaced in azimuth, are in the form of truncated sectors of the cylinder's end-faces. This theory is applied to the test-masses for the Satellite Test of the Equivalence Principle (STEP) experiment, for which four grooves have been assumed, and an expression for the axialforce is derived which is more than 10⁴ times faster to compute than a Monte-Carlo integration of similar accuracy. Following this analysis it is suggested that the STEP test-masses should carry at least 6 grooves. This theory has wider application to gravitational problems involving general sectored cylindrical bodies.     

Thermoluminescence of KMgF3(RE) crystals

Optical properties of pure and RE doped KMgF₃ crystals were studied. Thermoluminescence curves are independent of the introduced impurity for all dopant besides europium. Emission, radiation damage and TL are found to be significantly dependent on the types of Eu-dopant added to the melt: europium fluoride or oxide. An intensive high temperature TL peak at 390°C in KMgF₃(Eu₂O₃) may be used as a dosimetric one not only for ionizing but also for UV radiation.     

On modifications of random processes

Translated fromZapiski Nauchnykh Seminarov POMI, Vol. 194, pp. 150–169, 1992.     

Formation of the structure and effective properties of composite material in the manufacture of shells with cross-ply reinforcement

Conclusion The proposed model of formation of the reinforcing framework in the manufacture of an axisymmetric shell by the CPW method makes it possible to numerically determine the thicknesses and rates of filling the layers, reinforcement angles as a function of the main parameters of the technological process, geometry of the mandrel, and characteristics of the reinforcing filament. It was established that the thicknesses of the layers, reinforcement rates and angles, and, as a consequence, the effective stiffness characteristics of the composite are substantially variable both along the meridian and over the thickness of the shell.Translated from Mekhanika Kompozitnykh Materialov, No. 5, pp. 609–617, September–October, 1992.The authors thank V. A. Frolov for the experimental results.