Saraca asoca is an IUCN red-listed tree species that extensively famous in the Ayurvedic medicine field.
Saraca asoca (Roxb.) de Wilde belongs to the family
Fabaceae, has been used to treat various gynecological disorders, bacterial infections, worm infestations, haemmorhagic dysentery, uterine pain, skin diseases, cancer, circulatory, cardiovascular disorders, and many others. All parts of the
Saraca asoca have medicinal values. Numerous antioxidant compounds like flavonoids, catechin, beta-sitosterol, lignin glycosides are present in the bark, leaf, and flower of
Saraca asoca plant, which help to stabilize free radicals molecules that are associated with the development of cancer conditions. Currently in the cancer research study field new and more effective modes of natural therapies are recently being analyzed. Traditional medicines have been used for their preventative role against various diseases in the human population. Plant based therapy for cancer prevention is becoming more demanding due to its various unique properties such as natural chemical composition, less expensiveness, naturally available., easily orally administrable, significant chemo-protective activities, nontoxic to normal cells in the body, less side effects compared to other synthetic chemotherapeutic drugs. The chemotherapeutic drugs will be harmful to both cancer and normal cells. Additionally, some common side effects or health consequences like vomiting, nausea, bleeding, hair fall, alopecia, hyperuricemia, thrombocytopenia, bone marrow depression, mucositis are very common after chemotherapeutic drug treatment in cancer. This review paper summarizes the evidences which agree with the fact that flavonoids and other phenolic compounds in
Saraca asoca plant possess significant antioxidant activity and an efficient chemopreventive characteristic against different types of cancer. This paper reviews the anticancer activities of
Saraca asoca bark and flower and discusses the potential preventive roles of phenolic and flavonoids compounds, present in bark and flower of
Saraca asoca in the cancer treatment process.
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