全文获取类型
收费全文 | 3911篇 |
免费 | 89篇 |
国内免费 | 21篇 |
专业分类
化学 | 2718篇 |
晶体学 | 42篇 |
力学 | 48篇 |
数学 | 181篇 |
物理学 | 1032篇 |
出版年
2023年 | 16篇 |
2021年 | 33篇 |
2020年 | 43篇 |
2019年 | 54篇 |
2018年 | 38篇 |
2017年 | 21篇 |
2016年 | 54篇 |
2015年 | 66篇 |
2014年 | 63篇 |
2013年 | 162篇 |
2012年 | 169篇 |
2011年 | 222篇 |
2010年 | 103篇 |
2009年 | 139篇 |
2008年 | 204篇 |
2007年 | 210篇 |
2006年 | 216篇 |
2005年 | 175篇 |
2004年 | 167篇 |
2003年 | 155篇 |
2002年 | 168篇 |
2001年 | 131篇 |
2000年 | 106篇 |
1999年 | 69篇 |
1998年 | 51篇 |
1997年 | 56篇 |
1996年 | 52篇 |
1995年 | 41篇 |
1994年 | 53篇 |
1993年 | 62篇 |
1992年 | 74篇 |
1991年 | 58篇 |
1990年 | 50篇 |
1989年 | 57篇 |
1988年 | 43篇 |
1987年 | 56篇 |
1986年 | 47篇 |
1985年 | 55篇 |
1984年 | 51篇 |
1983年 | 39篇 |
1982年 | 27篇 |
1981年 | 41篇 |
1980年 | 30篇 |
1979年 | 48篇 |
1978年 | 40篇 |
1977年 | 25篇 |
1976年 | 31篇 |
1975年 | 24篇 |
1974年 | 28篇 |
1973年 | 21篇 |
排序方式: 共有4021条查询结果,搜索用时 93 毫秒
111.
Phenols are deprotected with weak bases from their tert-butoxycarbonyl (Boc) derivatives. Boc deprotection with bases can avoid side reactions during the deprotection with acids. We note the lability of the Boc to bases and are able to utilize it as a new cleavage condition for synthetic studies. 相似文献
112.
Ishimitsu S Kaihara A Yoshii K Tsumura Y Nakamura Y Tonogai Y 《Journal of AOAC International》2001,84(4):1172-1178
A method was developed for determination of the herbicide clethodim (C0) and its oxidation metabolites clethodim sulfoxide (C1) and clethodim sulfone (C2) in agricultural products. Upon extraction, both C0 and C1 were oxidized to C2 by m-chloroperoxybenzoic acid, and C2 was determined by liquid chromatography (LC). The C2 peak was confirmed by liquid chromatography/mass spectrometry (LC/MS) with electrospray ionization (ESI). Recoveries of C0 from radish, tomato, onion, sweet potato, kidney bean, carrot, cabbage, and lettuce ranged from 91 to 118% following fortification at 0.05-1.0 ppm. The detection limit of C2 in crops was 0.01 ppm (S/N > 3). The fortified samples of onion, sweet potato, kidney bean, and carrot were confirmed by LC/MS (ESI), and the peak of C2 was detected. 相似文献
113.
114.
3-Epi-6,7-dideoxyxestobergsterol A (2), an analogue of xestobergsterol A, has been synthesized from dehydroepiandrosterone (3) in 15 steps. The key synthetic intermediate, 15beta,16alpha-dioxypregn-17(20)E-ene derivative 8, was prepared from the corresponding 15beta,16beta-epoxide 6 by treating with acetic acid and titanium tetraisopropoxide. The 23-oxo side chain was constructed stereoselectively by orthoester Claisen rearrangement of 8 followed by introduction of an isobutyl group. Basic treatment of the 15,23-diketone 12 followed by deprotection gave the title compound 2. 相似文献
115.
Y Nishikawa T Shindo K Ishii H Nakamura T Kon H Uno J Matsumoto 《Chemical & pharmaceutical bulletin》1989,37(5):1256-1259
A new series of oxopyridinecarboxamide derivatives 3a--g and 5a were synthesized and evaluated for their antiallergic activity. 1,4-Dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxamides 3a and 5a exhibited potent antiallergic activity (inhibitory rates of 80.7 and 88.3%, respectively, at 20 mg/kg, p.o.) in the rat passive cutaneous anaphylaxis (PCA) test and also exhibited much more potent in vitro inhibitory activity than caffeic acid against the enzyme 5-lipoxygenase (5-LO). Their in vitro antihistamine activity, however, was weaker than that of ketotifen. Compounds 3a and 5a are viewed as promising candidates for antiallergic agents. 相似文献
116.
117.
118.
Fullerene cyclopentadienide (PhCH(2))(2)Ph(3)C(60)(-) and indenide (PhCH(2))(2)PhC(60)(-), each bearing two different organic groups, were efficiently synthesized through regioselective reactions of 1,4-(PhCH(2))(2)C(60) with an organocopper reagent (PhMgBr/CuBr.SMe(2)) or a Grignard reagent (PhMgBr) followed by deprotonation with KO(t)()Bu. 相似文献
119.
H Miyazaki N Ohkawa N Nakamura T Ito T Sada T Oshima H Koike 《Chemical & pharmaceutical bulletin》1989,37(9):2379-2390
Six-membered lactone and tetrahydropyran analogues of platelet-activating factor (PAF), 4-11, and related antagonistic derivatives 41-46 were synthesized. None of the delta-lactones 4-7 showed PAF-like activities, while the corresponding cyclic ethers 8, 9 and 11 were slightly active. Some of the cyclic antagonists showed more potent inhibitory activities than the open chain antagonist CV-3988 against platelet aggregation (rabbit platelet-rich plasma, IC50) and hypotension (rat, ID50) induced by C16-PAF: e.g. dl-3-[6-[O-(trans-3-heptadecylcarbamoyloxytetrahydropyran-2- yl)methyl]phosphonoxy]hexylthiazolium (inner salt) (41d) (IC50 5.5 x 10(-7) M, ID50 0.046 mg/kg, i.v.); dl-3-[5-[O-(cis-3-heptadecylcarbamoylthiotetrahydropyran-2- yl)methyl]phosphonoxy]pentylthiazolium (inner salt) (43c) (IC50 5.7 x 10(-7) M, ID50 0.076 mg/kg, i.v.). 相似文献
120.
Nakamura Y Asami A Ogawa T Inokuma S Nishimura J 《Journal of the American Chemical Society》2002,124(16):4329-4335
The reactions of [60]fullerene with bis-o-quinodimethane precursors 3, 4, and 5 containing a dibenzo-18-crown-6, 24-crown-8 and 30-crown-10 moiety, respectively, were investigated. Both 3 and 4 provided trans-4 bisadducts 6a and 7a, respectively, as major product, though the selectivity in the latter was lower than that in the former. As minor product, 6b (cis-2) was produced from 3, while 7c (e) as well as 7b (cis-2) were produced from 4. Precursor 5 exclusively afforded e bisadduct 8 without any other regioisomers. These bisadducts showed different ionophoric properties from one another; for instance, 6a and 7b exhibited a high complexing ability toward the K+ ion, while 6b hardly showed complexation with any alkali metal ions. The selectivity coefficients (K(Na,K)(pot)) of 6a and 7b toward K+ over Na+ ion, determined with an ion-selective electrode, were much higher than that of dibenzo-18-crown-6. 相似文献