Analyzing mass spectrometry imaging data can be laborious and time consuming, and as the size and complexity of datasets grow, so does the need for robust automated processing methods. We here present a method for comprehensive, semi-targeted discovery of molecular distributions of interest from mass spectrometry imaging data, using widely available image similarity scoring algorithms to rank images by spatial correlation. A fast and powerful batch search method using a MATLAB implementation of structural similarity (SSIM) index scoring with a pre-selected reference distribution is demonstrated for two sample imaging datasets, a plant metabolite study using Artemisia annua leaf, and a drug distribution study using maraviroc-dosed macaque tissue.
We demonstrate an apparatus for measuring time-dependent x-ray diffraction. X-ray pulses from a synchrotron are diffracted by a pair of Si(111) crystals and detected with an x-ray streak camera that has single-shot resolution of better than 1 ps. The streak camera is driven by a photoconductive switch, which is triggered by 100-fs laser pulses at a repetition rate of 1 kHz. The laser and the streak camera are synchronized with the synchrotron pulses. In the averaging mode, trigger jitter results in 2-ps temporal resolution. We measured the duration of 5-keV pulses from the Advanced Light Source synchrotron to be 70ps. 相似文献
The monohydrates of strontium and barium hydroxide have been prepared by decomposition, under vacuum, of the corresponding octahydrates. X-ray powder data for both compounds are reported, together with that for anhydrous strontium hydroxide; the latter is included in order to clarify an apparent anomaly in the literature.
Zusammenfassung Es wurden die Monohydrate von Strontium und Bariumhydroxid im Vakuum aus den entsprechenden Octahydraten hergestellt. Röntgenographische Daten für beide Verbindungen sowie für wasserfreies Strontiumhydroxid wurden gegeben; für Letzteres, um gewisse Anom alien in der Literatur zu klären.
Résumé Préparation des hydroxydes de strontium et de baryum monohydratés par décomposition dans le vide des octohydrates correspondants. Etude par rayons X de ces composés ainsi que de l'hydroxyde de strontium anhydre, dans le but, pour ce dernier, d'élucider certaines anomalies de la littérature.
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The authors wish to thank Mr. A. Miller for taking the X-ray powder photographs. 相似文献
Shadowing trajectories are one of the most powerful ideas of modern dynamical systems theory, providing a tool for proving
some central theorems and a means to assess the relevance of models and numerically computed trajectories of chaotic systems.
Shadowing has also been seen to have a role in state estimation and forecasting of nonlinear systems. Shadowing trajectories
are guaranteed to exist in hyperbolic systems, but this is not true of nonhyperbolic systems, indeed it can be shown there
are systems that cannot have long shadowing trajectories. In this paper we consider what might be called shadowing pseudo-orbits. These are pseudo-orbits that remain close to a given pseudo-orbit, but have smaller mismatches between forecast state and verifying state. Shadowing pseudo-orbits play a useful role in the understanding and analysis
of gradient descent noise reduction, state estimation, and forecasting nonlinear systems, because their existence can be ensured
for a wide class of nonhyperbolic systems. New theoretical results are presented that extend classical shadowing theorems
to shadowing pseudo-orbits. These new results provide some insight into the convergence behaviour of gradient descent noise
reduction methods. The paper also discusses, in the light of the new results, some recent numerical results for an operational
weather forecasting model when gradient descent noise reduction was employed. 相似文献
