Potassium selective chromoionophores

The ionisable chromoionophores5 were synthesised from simple precursors. These chromoionophores extract alkali metal cations from aqueous solutions at pH > 7 into dichloromethane. The ratio of extraction coefficients for the chromoionophore5c for K⁺ and Na⁺ indicate that it has potential for use in optical fibre sensors for K⁺ in the presence of Na⁺, Mg²⁺ and Ca²⁺ at extracellular concentrations.This paper is dedicated to the memory of the late Dr C. J. Pedersen.     

P-AMINOBENZOIC ACID CAN SENSITIZE THE FORMATION OF PYRIMIDINE DIMERS IN DNA: DIRECT CHEMICAL EVIDENCE

Thymine-containing photoproducts with chromatographic properties similar to those of cyclobutyl pyrimidine dimers can be formed in [³H]-thymine-labeled DNA in solution by 313 nm ultraviolet radiation in the presence of para-aminobenzoic acid (PABA), a compound used in sunscreen preparations. In the absence of PABA, similar fluences of 313 nm radiation do not produce significant numbers of these photoproducts. The thymine-containing photoproducts can be reversed by 254 nm radiation so that the tritium label migrates with the mobility of thymine monomer, a behavior characteristic of thymine-containing cyclobutyl pyrimidine dimers. This result supports previous, but less direct, data from other laboratories indicating that PABA can sensitize dimer formation in the DNA of bacterial and mammalian cells.     

Cartan subalgebras, transverse measures and non-type-I Plancherel formulae

Two formulations are given of Plancherel Theory for locally compact second countable groups. The first applies to arbitrary such groups, and recovers the L²-norm of suitable functions on the group from data associated to the central decomposition of the regular representation. The second applies in particular to connected or discrete amenable groups, and uses data derived from the irreducible representations appearing in a decomposition over a Cartan subalgebra, and Connes' ideas of transverse measures and functions in the recovery process. Non-trivial examples are also given.     

连续波锁模Pr3+:YLF激光器

本文报导了采用氩离子激光器来泵浦Pr³⁺:YLF晶体,应用声光调制器实现了主动锁模;同时应用振动─高反射平面镜也实现了被动锁模,两种锁模均得到了ps光脉冲.据作者了解这是这种晶体材料的第一次锁模运转.     

A Structural Investigation of Some Terminally Cyano-Substituted Side Chain Liquid-Crystalline Polysiloxanes

A series of terminally cyano substituted side chain polysiloxanes have been characterized using optical microscopy, D.S.C., and X-ray diffraction. Values for the lamellar spacings, d, of the interdigitated smectic A phases were obtained, and the variations in d with temperature and length of the flexible aliphatic spacer are discussed. The spacing for m = 4, 5, and 6 increased regularly with m whereas the short m = 3 spacer gave an anomalously high value.     

Group actions on C*-algebras, 3-cocycles and quantum field theory

We study group extensions , where acts on a C^*-algebraA. Given a twisted covariant representation ,V of the pairA, we construct 3-cocycles on with values in the centre of the group generated byV(). These 3-cocycles are obstructions to the existence of an extension of byV() which acts onA compatibly with . The main theorems of the paper introduce a subsidiary invariant which classifies actions of onV() and in terms of which a necessary and sufficient condition for the the cohomology class of the 3-cocycle to be non-trivial may be formulated. Examples are provided which show how non-trivial 3-cocycles may be realised. The framework we choose to exhibit these essentially mathematical results is influenced by anomalous gauge field theories. We show how to interpret our results in that setting in two ways, one motivated by an algebraic approach to constrained dynamics and the other by the descent equation approach to constructing cocycles on gauge groups. In order to make comparisons with the usual approach to cohomology in gauge theory we conclude with a Lie algebra version of the invariant and the 3-cocycle.     

Ion channels from linear and branched bola-amphiphiles

The synthesis and characterization of the ion channel activity of three new bola-amphiphiles is described. These compounds are conceptually derived from a previously reported bis-cyclophane bola-amphiphile through opening of the cyclophanes to acyclic structures and were found to readily form ion channels in planar bilayer membranes as assessed by bilayer clamp single-channel analysis. All three compounds behaved very similarly: the dominant channels formed by all three are Ohmic with specific conductance of 10 +/- 1 pS (NaCl electrolyte) and 39 +/- 1 pS (CsCl electrolyte). Single-ion permeability ratios, determined from dissymmetric electrolyte experiments, showed the selectivity P(Cs(+)) > P(Na(+)) > P(Cl(-)). Less frequently, lower conductance channels were also observed to act independently of the dominant channels. The lifetimes of the dominant channels range from 70 to 280 ms for the three compounds with some very long-lived openings (20-40 s) observed for two of the three. The lower conductance states have shorter lifetimes. This study demonstrates that bis-macrocyclic compounds are not essential for channel formation by bola-amphiphiles, and opens a new class of channel-forming compounds for structure-activity optimization.