全文获取类型
收费全文 | 475960篇 |
免费 | 14419篇 |
国内免费 | 7710篇 |
专业分类
化学 | 249112篇 |
晶体学 | 6484篇 |
力学 | 23742篇 |
综合类 | 521篇 |
数学 | 67582篇 |
物理学 | 150648篇 |
出版年
2022年 | 3443篇 |
2021年 | 4013篇 |
2020年 | 4425篇 |
2019年 | 4306篇 |
2018年 | 13046篇 |
2017年 | 13715篇 |
2016年 | 10765篇 |
2015年 | 7145篇 |
2014年 | 8101篇 |
2013年 | 18778篇 |
2012年 | 20533篇 |
2011年 | 31172篇 |
2010年 | 19355篇 |
2009年 | 19184篇 |
2008年 | 26554篇 |
2007年 | 29714篇 |
2006年 | 15634篇 |
2005年 | 21090篇 |
2004年 | 15818篇 |
2003年 | 13868篇 |
2002年 | 11549篇 |
2001年 | 11556篇 |
2000年 | 9243篇 |
1999年 | 7602篇 |
1998年 | 6190篇 |
1997年 | 5844篇 |
1996年 | 6067篇 |
1995年 | 5467篇 |
1994年 | 5146篇 |
1993年 | 4838篇 |
1992年 | 5215篇 |
1991年 | 4980篇 |
1990年 | 4604篇 |
1989年 | 4348篇 |
1988年 | 4541篇 |
1987年 | 4190篇 |
1986年 | 4015篇 |
1985年 | 5671篇 |
1984年 | 5665篇 |
1983年 | 4605篇 |
1982年 | 4944篇 |
1981年 | 4958篇 |
1980年 | 4688篇 |
1979年 | 4790篇 |
1978年 | 4807篇 |
1977年 | 4708篇 |
1976年 | 4690篇 |
1975年 | 4595篇 |
1974年 | 4430篇 |
1973年 | 4642篇 |
排序方式: 共有10000条查询结果,搜索用时 62 毫秒
121.
122.
123.
E. V. Shadrina O. N. Malinkina T. G. Khonina A. B. Shipovskaya V. I. Fomina E. Yu. Larchenko N. A. Popova I. G. Zyryanova L. P. Larionov 《Russian Chemical Bulletin》2015,64(7):1633-1639
The biomimetic sol—gel synthesis of silicon—chitosan-containing glycerohydrogels was carried out using silicon tetraglycerolate as a precursor. It was found that chitosan accelerates gel formation in weakly acidic media. In more acidic media, the kinetics of the process changes according to the curve with a maximum, which can be attributed to different mechanisms of silanol condensation before and after the isoelectric point. The investigated silicon—chitosan-containing glycerohydrogels exhibit antibacterial, anti-inflammatory, and wound healing activity. The synthesized hybrid glycerohydrogels are promising materials for biomedical applications. 相似文献
124.
125.
Highly dispersed palladium nanoclusters incorporated in amino‐functionalized silica spheres for the selective hydrogenation of succinic acid to γ‐butyrolactone
下载免费PDF全文
![点击此处可从《应用有机金属化学》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Highly dispersed palladium nanoclusters incorporated on amino‐functionalized silica sphere surfaces (Pd/SiO2‐NH2) were fabricated by a simple one‐pot synthesis utilizing 3‐(2‐aminoethylamino)propyltrimethoxysilane (AAPTS) as coordinating agent. Uniform palladium nanoclusters with an average size of 1.1 nm can be obtained during the co‐condensation of tetraethyl orthosilicate and AAPTS owing to the strong interaction between palladium species and amino groups in AAPTS. The palladium particle size can be controlled by addition of AAPTS and plays a significant role in the catalytic performance. The Pd/SiO2‐NH2 catalyst exhibits high catalytic activity for succinic acid hydrogenation with 100% conversion and 94% selectivity towards γ‐butyrolactone using 1,4‐dioxane as solvent at 240°C and 60 bar for 4 h. Moreover, the Pd/SiO2‐NH2 catalyst is robust and readily reusable without loss of its catalytic activity. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
126.
Monodisperse aqueous upconverting nanoparticles (UCNPs) were covalently immobilized on aldehyde modified cellulose paper via reduction amination to develop a luminescence resonance energy transfer (LRET)-based nucleic acid hybridization assay. This first account of covalent immobilization of UCNPs on paper for a bioassay reports an optically responsive method that is sensitive, reproducible and robust. The immobilized UCNPs were decorated with oligonucleotide probes to capture HPRT1 housekeeping gene fragments, which in turn brought reporter conjugated quantum dots (QDs) in close proximity to the UCNPs for LRET. This sandwich assay could detect unlabeled oligonucleotide target, and had a limit of detection of 13 fmol and a dynamic range spanning nearly 3 orders of magnitude. The use of QDs, which are excellent LRET acceptors, demonstrated improved sensitivity, limit of detection, dynamic range and selectivity compared to similar assays that have used molecular fluorophores as acceptors. The selectivity of the assay was attributed to the decoration of the QDs with polyethylene glycol to eliminate non-specific adsorption. The kinetics of hybridization were determined to be diffusion limited and full signal development occurred within 3 min. 相似文献
127.
128.
Xiaoshuang Luo Xinxian Qin Zhengyi Liu Dan Chen Weiwei Yu Kankan Zhang Deyu Hu 《Biomedical chromatography : BMC》2020,34(1):e4694
A simple and rapid analytical method for the detection of trifloxystrobin, trifloxystrobin acid and tebuconazole in soil, brown rice, paddy plants and rice hulls was established and validated by liquid chromatography with tandem mass spectrometry. Acceptable linearity (R2 > 0.99), accuracy (average recoveries of 74.3–108.5%) and precision (intra- and inter-day relative standard deviations of 0.9–8.8%) were obtained using the developed determination approach. In the field trial, the half-lives of trifloxystrobin and tebuconazole in paddy plants were 5.7–8.3 days in three locations throughout China, and the terminal residue concentrations of trifloxystrobin and tebuconazole were <100 and 500 μg/kg (maximum residue limits set by China), respectively, at harvest, which indicated that, based on the recommended application procedure, trifloxystrobin and tebuconazole are safe for use on rice. The risk assessment results demonstrated that, owing to risk quotient values of both fungicides being <100%, the potential risk of trifloxystrobin and tebuconazole on rice was acceptable for Chinese consumers. These data could provide supporting information for the proper use and safety evaluation of trifloxystrobin and tebuconazole in rice. 相似文献
129.
Renny Mathew Karolina A. Uchman Lydia Gkoura Chris J. Pickard Maria Baias 《Magnetic resonance in chemistry : MRC》2020,58(11):1018-1025
A combined experimental and computational approach was used to distinguish between different polymorphs of the pharmaceutical drug aspirin. This method involves the use of ab initio random structure searching (AIRSS), a density functional theory (DFT)-based crystal structure prediction method for the high-accuracy prediction of polymorphic structures, with DFT calculations of nuclear magnetic resonance (NMR) parameters and solid-state NMR experiments at natural abundance. AIRSS was used to predict the crystal structures of form-I and form-II of aspirin. The root-mean-square deviation between experimental and calculated 1H chemical shifts was used to identify form-I as the polymorph present in the experimental sample, the selection being successful despite the large similarities between the molecular environments in the crystals of the two polymorphs. 相似文献
130.
Yalda Liaghati Mobarhan Ronald Soong Daniel Lane Andre J. Simpson 《Magnetic resonance in chemistry : MRC》2020,58(5):427-444
Traditionally, due to different hardware requirements, nuclear magnetic resonance (NMR) has developed as two separate fields: one dealing with solids, and one with solutions. Comprehensive multiphase (CMP) NMR combines all electronics and hardware (magic angle spinning [MAS], gradients, high power Radio Frequency (RF) handling, lock, susceptibility matching) into a universal probe that permits a comprehensive study of all phases (i.e., liquid, gel-like, semisolid, and solid), in intact samples. When applied in vivo, it provides unique insight into the wide array of bonds in a living system from the most mobile liquids (blood, fluids) through gels (muscle, tissues) to the most rigid (exoskeleton, shell). In this tutorial, the practical aspects of in vivo CMP NMR are discussed including: handling the organisms, rotor preparation, sample spinning, water suppression, editing experiments, and finishes with a brief look at the potential of other heteronuclei (2H, 15N, 19F, 31P) for in vivo research. The tutorial is aimed as a general resource for researchers interested in developing and applying MAS-based approaches to living organisms. Although the focus here is CMP NMR, many of the approaches can be adapted (or directly applied) using conventional high-resolution magic angle spinning, and in some cases, even standard solid-state NMR probes. 相似文献